Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 33.00 | |
50 mg | In stock | $ 47.00 | |
100 mg | In stock | $ 68.00 | |
500 mg | In stock | $ 165.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS. |
In vivo | TRIM is a poor inhibitor of bovine aortic endothelial NOS with an IC50 of 1057.5 microM. TRIM (10-50 mg kg-1) administered i.p. exhibits dose-related antinociceptive activity in the mouse (assessed as inhibition of late phase formalin-induced hindpaw licking behaviour) with an ED50 of 85.8 mumol kg-1. In contrast, TRIM (50 mg kg-1, i.p.) failed to influence mean arterial blood pressure in the urethane-anaesthetized mouse[1]. |
Synonyms | 1-(2-Trifluoromethylphenyl)imidazole |
Molecular Weight | 212.17 |
Formula | C10H7F3N2 |
CAS No. | 25371-96-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 2.12 mg/mL (10 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
TRIM 25371-96-4 Immunology/Inflammation NOS nNOS 1-(2-Trifluoromethylphenyl)imidazole eNOS Inhibitor inhibit anxiolytic-like effects NO Synthase Nitric oxide synthases iNOS antidepressant inhibitor