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Tauro-Obeticholic acid

Catalog No. T13092 CAS 863239-61-6

Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).

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Tauro-Obeticholic acid Chemical Structure

Tauro-Obeticholic acid, CAS 863239-61-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 119.00
5 mg	In stock	$ 289.00
10 mg	In stock	$ 436.00
25 mg	In stock	$ 722.00
50 mg	In stock	$ 987.00
100 mg	In stock	$ 1,380.00
1 mL * 10 mM (in DMSO)	In stock	$ 368.00

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Purity: 99.82%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
In vitro	Obeticholic acid and taurine are conjugated in the liver to form taurine-obeticholic acid, which is secreted into the bile. Microorganisms in the ileum and colon can dissociate taurine-cholesteric acid and convert it into the parent drug, which can then be reabsorbed or excreted in feces.

Molecular Weight	527.76
Formula	C28H49NO6S
CAS No.	863239-61-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (94.74 mM)

References and Literature

1. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max NO PAINS Compound Library Natural Product Library for HTS Bioactive Compound Library Metabolism Compound Library Anti-Metabolism Disease Compound Library Lipid Metabolism Compound Library Nuclear Receptor Compound Library Natural Product Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tauro-Obeticholic acid 863239-61-6 Metabolism FXR microorganisms colon NR1H4 TauroObeticholic acid inhibit ileum Inhibitor Tauro Obeticholic acid metabolite，liver inhibitor

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