Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | In stock | $ 41.00 | |
50 mg | In stock | $ 58.00 | |
100 mg | In stock | $ 90.00 | |
200 mg | In stock | $ 112.00 | |
500 mg | In stock | $ 148.00 | |
1 g | In stock | $ 234.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist. |
Targets&IC50 | angiotensin II type 1 receptor (AT1):9.2 nM |
Cell Research | Telmisartan is prepared as a 10 mM stock solution in DMSO. Cell proliferation is assayed using the CCK-8 cell counting kit. Briefly, 5×103 cells are seeded into each well of a 96-well plate and cultured in 100 μL of RPMI-1640 supplemented with 10% FBS. After 24 h, ARBs (telmisartan, irbesartan, losartan, and valsartan at 0, 1, 10, or 100 μM) or vehicle is added to each well, and cells are cultured for an additional 48 h. CCK-8 reagent (10 μL) is added to each well, and the plates are incubated at 37°C for 3 h. The absorbance is measured at 450 nm using a microplate reader. |
Synonyms | BIBR 277 |
Molecular Weight | 514.62 |
Formula | C33H30N4O2 |
CAS No. | 144701-48-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10.3 mg/mL (20 mM)
You can also refer to dose conversion for different animals. More
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