Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 38.00 | |
5 mg | In stock | $ 61.00 | |
10 mg | In stock | $ 93.00 | |
25 mg | In stock | $ 153.00 | |
50 mg | In stock | $ 193.00 | |
100 mg | In stock | $ 343.00 | |
500 mg | In stock | $ 822.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 77.00 |
Description | Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. |
In vivo | Telotristat Etiprate (300 mg/kg p.o.) significantly reduces 5-HT in the gut and blood, but not brain 5-HT. Telotristat Etiprate (200 mg/kg p.o.) alleviates the severity of trinitrobenzene sulfonic acid (TNBS)-induced colitis with lower expression of some genes encoding inflammation-related cytokines and chemokines in mice. [2] |
Synonyms | LX1606 (Hippurate), LX 1606 Hippurate |
Molecular Weight | 754.15 |
Formula | C27H26ClF3N6O3·C9H9NO3 |
CAS No. | 1137608-69-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 100 mg/mL (132.59 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Telotristat Etiprate 1137608-69-5 Metabolism Hydroxylase LX-1606 LX1606 (Hippurate) LX 1606 inhibit LX 1606 Hippurate LX1606 Tryptophan Hydroxylase Hippurate Inhibitor inhibitor