Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be used in the synthesis of PROTACs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 51.00 | |
10 mg | In stock | $ 74.00 | |
25 mg | In stock | $ 122.00 | |
50 mg | In stock | $ 178.00 | |
100 mg | In stock | $ 268.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 64.00 |
Description | Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-PEG-C2-NH2 hydrochloride can be used in the synthesis of PROTACs. |
In vitro | PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 454.862 |
Formula | C19H23ClN4O7 |
CAS No. | 2204226-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mg/mL (219.85 mM), Sonication is recommended.
DMSO: 125 mg/mL (274.81 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 2204226-02-6 Others PROTAC E3 Ligase Ligand-Linker Conjugate Inhibitor Thalidomide-O-amido-PEG-C2-NH2 Hydrochloride Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride ThalidomideOamidoPEGC2NH2 hydrochloride inhibit Thalidomide O amido PEG C2 NH2 hydrochloride E3 Ligase Ligand-Linker Conjugates inhibitor