Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group, in turn, is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 34.00 | |
100 mg | In stock | $ 48.00 | |
200 mg | In stock | $ 58.00 | |
1 g | In stock | $ 90.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitrite anions and metronidazole. Metronidazole's nitro group, in turn, is reduced via the parasite ferredoxin, thereby generating a series of free nitro radicals including nitro anions. Toxicity is achieved via depletion of sulfhydryl groups and DNA strand breaks with multiple hits having an additive effect and ultimately leading to cell death. |
Synonyms | CP12574 |
Molecular Weight | 247.27 |
Formula | C8H13N3O4S |
CAS No. | 19387-91-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 46 mg/mL (186 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. More
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Tinidazole 19387-91-8 Microbiology/Virology Antibacterial Antibiotic inhibit infections antimicrobial Inhibitor anaerobic CP 12574 Bacterial CP12574 CP-12574 bacteria inhibitor