Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tradipitant (VLY-686) is an antagonist of neurokinin-1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 55.00 | |
2 mg | In stock | $ 77.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 347.00 | |
50 mg | In stock | $ 516.00 | |
100 mg | In stock | $ 736.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 159.00 |
Description | Tradipitant (VLY-686) is an antagonist of neurokinin-1. |
In vitro | Tradipitant binds to sections of guinea pig brain with a distribution similar to that previously reported for NK-1 receptors. Areas with the highest density are the accessory olfactory nucleus, anteroventral thalamic nucleus, paraventricular hypothalamic nucleus central amygdaloid nucleus (lateral), and the medial amygdaloid nucleus [1]. |
In vivo | Tradipitant (intravenously administered) treatment localizes in the guinea pig brain and has a distribution similar to that described for the NK-1 receptor using agonist or antagonist radioligands [1]. |
Synonyms | VLY-686, LY686017 |
Molecular Weight | 587.9 |
Formula | C28H16ClF6N5O |
CAS No. | 622370-35-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/ml (102.06 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Tradipitant 622370-35-8 GPCR/G Protein Neuroscience Neurokinin receptor VLY 686 Neurokinin Receptor VLY-686 Inhibitor VLY686 LY-686017 LY 686017 NK receptor LY686017 Tachykinin receptor inhibit inhibitor