Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Triclocarban (Cutisan), an antimicrobial agent, is used in personal cleaning products.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 48.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 54.00 |
Description | Triclocarban (Cutisan), an antimicrobial agent, is used in personal cleaning products. |
In vitro | Triclocarban (300 nM) potentiates the cytotoxicity of 300 μM H2O2 in rat thymocytes. Triclocarban (300 nM) itself does not increase the population of dead cells, it facilitates the process of cell death induced by H2O2, resulting in further increase in the population of dead cells [1]. Triclocarban exerts estrogenic activities by inducing luciferase activities in an ER reporter gene assay, promoting the proliferation of the MCF-7 cells, up-regulating the expression of pS2 and down-regulating ERα expression at both the mRNA and protein levels in the MCF-7 cells [2]. |
In vivo | Triclocarban, when used in soap during showering, is significantly absorbed by humans, with its peak concentration (Cmax) in whole blood ranging between 23 nM and 530 nM[1]. While exposure to triclocarban during pregnancy does not impact the viability of pregnancy, exposure during lactation adversely affects offspring survival[3]. |
Synonyms | Solubacter, Cutisan, Procutene, 3,4,4′-Trichlorocarbanilide |
Molecular Weight | 315.58 |
Formula | C13H9Cl3N2O |
CAS No. | 101-20-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL
You can also refer to dose conversion for different animals. More
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Triclocarban 101-20-2 Microbiology/Virology Antibacterial Bacterial Solubacter endocrine-disrupting inhibit Cutisan Procutene 3,4,4′-Trichlorocarbanilide personal products cleaning Inhibitor antimicrobial inhibitor