Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
2 mg | In stock | $ 74.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 197.00 | |
25 mg | In stock | $ 353.00 | |
50 mg | In stock | $ 538.00 | |
100 mg | In stock | $ 778.00 | |
500 mg | In stock | $ 1,590.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 133.00 |
Description | Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM). |
Targets&IC50 | PDGFRβ:5 μM, FLK1:9.3 μM |
In vitro | In glioblastoma cells, Tyrphostin AG1433 (0.1-100 μM; 72 hours; GB8B cells) treatment induces moderate cytotoxicity [1]. |
In vivo | Tyrphostin AG1433 is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day-old chicken embryos, and prevents the formation of new yessels under the pellets[2]. |
Synonyms | SU1433, AG1433 |
Molecular Weight | 266.29 |
Formula | C16H14N2O2 |
CAS No. | 168835-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 62.5 mg/mL (234.71 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Tyrphostin AG1433 168835-90-3 Angiogenesis Tyrosine Kinase/Adaptors VEGFR PDGFR cytotoxicity PDGFRβ Tyrphostin AG-1433 kinases Vascular endothelial growth factor receptor SU 1433 SU1433 Tyrphostin AG 1433 Platelet-derived growth factor receptor AG1433 AG-1433 angiogenesis,tyrosine inhibit AG 1433 VEGFR-2 Inhibitor ATM SU-1433 inhibitor