Powder: -20°C for 3 years | In solvent: -80°C for 1 year
U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 65.00 | |
5 mg | In stock | $ 153.00 | |
10 mg | In stock | $ 226.00 | |
25 mg | In stock | $ 529.00 | |
50 mg | In stock | $ 936.00 | |
100 mg | In stock | $ 1,260.00 |
Description | U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors. |
In vitro | In the alpha 1 beta 2 gamma 2 subtype of GABAA receptors expressed in human embryonic kidney cells, U 89843A dose-dependently enhanced 5 microM GABA-induced Cl- currents with a maximal enhancement of 362 +/- 91%, a half-maximal concentration of 2 +/- 0.4 microM and a slope factor of 1.1 +/- 0.4. U 89843A also inhibited [35S]t-butylbicyclophosphorothionate binding in rat cerebrocortical membranes with a similar half-maximal inhibitory concentration[1]. |
Molecular Weight | 285.39 |
Formula | C16H23N5 |
CAS No. | 157013-32-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: <16.09mg/ml
H2O: <8.05mg/mL
You can also refer to dose conversion for different animals. More
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U 89843A 157013-32-6 Membrane transporter/Ion channel Neuroscience GABA Receptor inhibitor inhibit