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Search Results for " urmc099 "

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Compounds

Cat No. Product Name Synonyms Targets
T6057 URMC-099 MEK , LRRK2 , IGF-1R , Bcr-Abl , Syk , CDK , ROCK , MLK , VEGFR , DNA Alkylation , Trk receptor , SGK , c-Met/HGFR , Src , Autophagy , Aurora Kinase
URMC-099 is an orally bioavailable, brain penetrant MLK inhibitor (IC50: 19/42/14/150 nM, for MLK1/MLK2/MLK3/DLK), and also inhibits LRRK2 activity (IC50: 11 nM).
TargetMol