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Uridine-5'-diphosphate disodium salt

Catalog No. T4706   CAS 27821-45-0
Synonyms: UDP disodium salt, Uridine 5'-diphosphate disodium salt hyd

Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.

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Uridine-5'-diphosphate disodium salt Chemical Structure
Uridine-5'-diphosphate disodium salt, CAS 27821-45-0
Pack Size Availability Price/USD Quantity
50 mg In stock $ 32.00
100 mg In stock $ 45.00
500 mg In stock $ 97.00
1 mL * 10 mM (in DMSO) In stock $ 48.00
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Purity: 98.6%
Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Uridine-5'-diphosphate disodium salt (UDP disodium salt) is a specific agonist of the P2Y6 receptors (EC50 = 13 nM for human P2Y6), stimulating the production of inflammatory mediators, phagocytosis, and vasoconstriction. Uridine-5'-diphosphate disodium salt also acts as an antagonist of P2Y14.
Targets&IC50 P2Y6 receptor:13 nM (EC50)
Synonyms UDP disodium salt, Uridine 5'-diphosphate disodium salt hyd
Molecular Weight 450.14
Formula C9H14N2Na2O12P2
CAS No. 27821-45-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (133.89 mM)

TargetMolReferences and Literature

1. Jacobson, K.A., et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 5(1), 75-89 (2009). 2. Abbracchio, M.P., et al. International Union of Pharmacology LVIII: Update on the P2Y G protein-coupled nucleotide receptors: From molecular mechanisms and pathophysiology to therapy. Pharmacological Reviews 58(3), 281-341 (2006).

Related compound libraries

This product is contained In the following compound libraries:
GPCR Compound Library Human Endogenous Metabolite Library Bioactive Compounds Library Max Natural Product Library for HTS Nucleotide Compound Library Natural Product Library Anti-infective Natural Product Library Anti-Infection Compound Library Anti-Cancer Compound Library Anti-Aging Compound Library

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Keywords

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