Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vorasidenib (PVM/MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 48.00 | |
2 mg | In stock | $ 72.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 378.00 | |
50 mg | In stock | $ 568.00 | |
100 mg | In stock | $ 815.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 109.00 |
Description | Vorasidenib (PVM/MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively) |
Targets&IC50 | IDH1 (R132H):31.9 nM , IDH2 (R140Q):31.7 nM |
In vivo | Vorsidenib reduces tumor growth in a TS603-IDH1R132H mouse xenograft model when administered at a dose of 50 mg/kg. |
Synonyms | PVM/MA, AG-881 |
Molecular Weight | 414.74 |
Formula | C14H13ClF6N6 |
CAS No. | 1644545-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (301.39 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Vorasidenib 1644545-52-7 Metabolism Isocitrate Dehydrogenase (IDH) PVM/MA inhibit AG 881 AG-881 Inhibitor AG881 inhibitor