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WAY-200070

Catalog No. T3958 CAS 440122-66-7

Synonyms: WAY 200070

WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

WAY-200070, CAS 440122-66-7

Pack Size	Availability	Price/USD
1 mg	In stock	$ 36.00
2 mg	In stock	$ 50.00
5 mg	In stock	$ 80.00
10 mg	In stock	$ 113.00
25 mg	In stock	$ 243.00
50 mg	In stock	$ 430.00
100 mg	In stock	$ 636.00
500 mg	In stock	$ 1,360.00
1 mL * 10 mM (in DMSO)	In stock	$ 80.00

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Purity: 99.46%

Purity: 99.21%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).
Targets&IC50	ERRβ:2.3 nM
In vivo	In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation. In addition, there are examples where N-myristoylation occurs post-translationally, when a hidden myristoylation pattern is exposed.

Synonyms	WAY 200070
Molecular Weight	306.11
Formula	C13H8BrNO3
CAS No.	440122-66-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (118.32 mM)

References and Literature

1. Hughes ZA, et al. WAY-22020070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent. Neuropharmacology. 2008 Jun;54(7):1136-42. 2. Clipperton Allen AE, et al. Agonistic behavior in males and females: effects of an estrogen receptor beta agonist in gonadectomized and gonadally intact mice. Psychoneuroendocrinology. 2010 Aug;35(7):12008-22. 3. Clipperton AE, et al. Differential effects of estrogen receptor alpha and beta specific agonists on social learning of food preferences in female mice. Neuropsychopharmacology. 2008 Sep;33(10):2362-75. 4. Weiser MJ, et al. Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology. 2009 Apr;150(4):1817-25.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Anti-Ovarian Cancer Compound Library NO PAINS Compound Library Anti-Cardiovascular Disease Compound Library Bioactive Compounds Library Max Anti-Cancer Compound Library Anti-Aging Compound Library Endocrinology-Hormone Compound Library Target-Focused Phenotypic Screening Library Immunology/Inflammation Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

WAY-200070 440122-66-7 Endocrinology/Hormones Estrogen/progestogen Receptor Estrogen Receptor/ERR Inhibitor inhibit WAY200070 WAY 200070 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.