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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6731 | WYE-354 | Apoptosis , PI3K , Autophagy , mTOR | |
WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ ... |