Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 297.00 | |
50 mg | In stock | $ 549.00 | |
100 mg | In stock | $ 796.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 98.00 |
Description | XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively). |
Targets&IC50 | M-current:0.98 μM, Kv7.2 channel:0.71 μM, Kv7.1 channel:0.75 μM, Kv7.2/Kv7.3 channel:0.6 μM |
Molecular Weight | 449.37 |
Formula | C26H22Cl2N2O |
CAS No. | 122955-13-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (26.7 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XE 991 dihydrochloride 122955-13-9 Membrane transporter/Ion channel Others Potassium Channel XE-991 Dihydrochloride XE 991 Dihydrochloride inhibit XE991 KcsA Inhibitor XE 991 XE-991 XE991 Dihydrochloride inhibitor