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Xanthopurpurin

Catalog No. TN2315   CAS 518-83-2

Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation.

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Xanthopurpurin Chemical Structure
Xanthopurpurin, CAS 518-83-2
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1 mg In stock $ 105.00
5 mg In stock $ 242.00
10 mg In stock $ 355.00
25 mg In stock $ 598.00
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Purity: 98.04%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-induced platelet aggregation.
In vitro The cytotoxicity of RCAP toward MA-104 cells was evaluated using the WST-8 assay. Colloidal gold method and real time polymerase chain reaction (qPCR) assay were used to confirm the findings of the antiviral assay. Then, 4',6-diamidino-2-phenylindole (DAPI) staining method was subsequently used to investigate the mode of death among the cells. And the representative components of aqueous extract were isolated and identified. It was shown that both the viability of MA-104 cells and the viral load were reduced with increasing concentration of the extract. DAPI staining showed that virus-induced apoptosis was the cause of the low cell viability and viral load, an effect which was accelerated with incubation in the aqueous herbal extract. The major compounds postulated to exhibit this activity were isolated from the aqueous herbal extract and identified to be compounds Xanthopurpurin and Vanillic Acid[1]
Source
Molecular Weight 240.21
Formula C14H8O4
CAS No. 518-83-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Sun Y, et al. In vitro Antiviral Activity of Rubia cordifolia Aerial Part Extract against Rotavirus. Front Pharmacol. 2016 Sep 13;7:308. 2. M I Chung, et al. Antiplatelet constituents of formosan Rubia akane. J Nat Prod. 1994 Feb;57(2):313-6.

Related compound libraries

This product is contained In the following compound libraries:
Natural Product Library for HTS RO5 Drug-like Natural Product Library

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Keywords

Xanthopurpurin 518-83-2 Microbiology/Virology Others Platelet aggregation Antifection Inhibitor inhibit Purpuroxanthin inhibitor

 

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