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Zoledronic Acid

Catalog No. T6739 CAS 118072-93-8

Synonyms: CGP-4244, CGP42446A, Zoledronate, CGP 42446, ZOL 446, Zometa

Zoledronic Acid (ZOL 446) is a bisphosphonate. Zoledronic Acid (ZOL 446) is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalcemia of malignancy and can be helpful for treating pain from bone metastases. An annual dose of Zoledronate may also prevent recurring fractures in patients with a previous hip fracture. Zoledronic Acid (ZOL 446) is a single 5 mg infusion for the treatment of Paget's disease of bone. In 2007, the FDA also approved Reclast for the treatment of postmenopausal osteoporosis.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Zoledronic Acid, CAS 118072-93-8

Pack Size	Availability	Price/USD
10 mg	In stock	$ 32.00
25 mg	In stock	$ 47.00
50 mg	In stock	$ 77.00
100 mg	In stock	$ 127.00
200 mg	In stock	$ 188.00
500 mg	In stock	$ 317.00

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Purity: 99.93%

Purity: 98%

Purity: 95.15%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	CGP-4244, CGP42446A, Zoledronate, CGP 42446, ZOL 446, Zometa
Molecular Weight	272.09
Formula	C5H10N2O7P2
CAS No.	118072-93-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

1.1eq. NaOH: 13.6 mg/mL (50 mM)

References and Literature

1. Jagdev SP, et al. Br J Cancer, 2001, 84(8), 1126-1134. 2. Viereck V, et al. Biochem Biophys Res Commun, 2002, 291(3), 680-686. 3. Croucher PI, et al. J Bone Miner Res, 2003, 18(3), 482-492.

Citations

1. Jiang Z, Qin L, Tang Y, et al. Human induced-T-to-natural killer cells have potent anti-tumour activities. Biomarker Research. 2022, 10(1): 1-22.

Related compound libraries

This product is contained In the following compound libraries：

EMA Approved Drug Library Drug Repurposing Compound Library Anti-Cancer Approved Drug Library Anti-Cancer Active Compound Library Anti-Cancer Clinical Compound Library Anti-Cancer Drug Library Bioactive Compounds Library Max Neural Regeneration Compound Library Bioactive Compound Library Anti-Lung Cancer Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Zoledronic Acid 118072-93-8 Apoptosis Autophagy Cell Cycle/Checkpoint Rho activity anti-cancer CGP-4244 Inhibitor CGP-42446 CGP42446A bisphosphonate Zoledronate CGP 4244 inhibit anti-resorptive CGP 42446 CGP4244 osteoclast ZOL446 ZOL 446 osteoporosis CGP42446 Zometa ZOL-446 inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.