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Boc-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs, crucial for uniting two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Description | Boc-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs, crucial for uniting two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | Boc-NH-PEG4-C2-Boc |
Molecular Weight | 421.531 |
Formula | C20H39NO8 |
Cas No. | 2138484-13-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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