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Cetirizine dihydrochloride

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Purity:100%

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COA HNMR HPLC

Cetirizine dihydrochloride

Catalog No. T0089Cas No. 83881-52-1

Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventional antihistamines, it does not cause side effects of drowsiness or anticholinergic.

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Pack Size	Price	Availability
50 mg	$36	In Stock
100 mg	$50	In Stock
200 mg	$72	In Stock
500 mg	$107	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Product Introduction

Bioactivity

Description	Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventional antihistamines, it does not cause side effects of drowsiness or anticholinergic.
Alias	P071, UCB P071, Cetirizine DiHCl

Chemical Properties

Molecular Weight	461.81
Formula	C21H27Cl3N2O3
Cas No.	83881-52-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 46.2 mg/mL (100 mM)

DMSO: 55 mg/mL (119.1 mM)

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1654 mL	10.8270 mL	21.6539 mL	108.2696 mL
5 mM	0.4331 mL	2.1654 mL	4.3308 mL	21.6539 mL
10 mM	0.2165 mL	1.0827 mL	2.1654 mL	10.8270 mL
20 mM	0.1083 mL	0.5413 mL	1.0827 mL	5.4135 mL
50 mM	0.0433 mL	0.2165 mL	0.4331 mL	2.1654 mL
100 mM	0.0217 mL	0.1083 mL	0.2165 mL	1.0827 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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