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DSPE-PEG13-TFP ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG13-TFP ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands linked together—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system for selective degradation of target proteins [1]. |
Molecular Weight | 1568.88 |
Formula | C77H138F4NO24P |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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