Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

HIV-1 integrase inhibitor 8

HIV-1 integrase inhibitor 8
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase, a critical enzyme necessary for the integration step in HIV replication [1].
Catalog No. T60742Cas No. 1568-80-5
Select Batch
Purity:98.01%
Contact us for more batch information
Resource Download

HIV-1 integrase inhibitor 8

Catalog No. T60742Cas No. 1568-80-5
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase, a critical enzyme necessary for the integration step in HIV replication [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
100 mg$40In Stock
200 mg$56In Stock
500 mg$92In Stock
1 g$133In Stock
Bulk & Custom
Add to Cart
Questions
View More

Related Compound Libraries of "HIV-1 integrase inhibitor 8"

Product Introduction

Bioactivity
Description
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase, a critical enzyme necessary for the integration step in HIV replication [1].
In vitro
HIV-1 integrase inhibitor 8 were tested against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn2+ as the cationic cofactor by gel assay, IC50=275μM and 231μM, respectively. HIV-1 integrase inhibitor 8 were retested using Mg2+ and the IC50 of against strand-transfer (ST) activities was 200μM. HIV-1 integrase inhibitor 8 inhibits MCV topoisomerase and DNA religation with IC50 of 500 µM and 200 µM, respectively. HIV-1 integrase inhibitor 8 induces cell cytotoxicity with LD50 of 20 μM in HeLa cells[1].
Chemical Properties
Molecular Weight308.41
FormulaC21H24O2
Cas No.1568-80-5
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (145.91 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2424 mL16.2122 mL32.4244 mL162.1219 mL
5 mM0.6485 mL3.2424 mL6.4849 mL32.4244 mL
10 mM0.3242 mL1.6212 mL3.2424 mL16.2122 mL
20 mM0.1621 mL0.8106 mL1.6212 mL8.1061 mL
50 mM0.0648 mL0.3242 mL0.6485 mL3.2424 mL
100 mM0.0324 mL0.1621 mL0.3242 mL1.6212 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy HIV-1 integrase inhibitor 8 | purchase HIV-1 integrase inhibitor 8 | HIV-1 integrase inhibitor 8 cost | order HIV-1 integrase inhibitor 8 | HIV-1 integrase inhibitor 8 chemical structure | HIV-1 integrase inhibitor 8 in vitro | HIV-1 integrase inhibitor 8 formula | HIV-1 integrase inhibitor 8 molecular weight