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MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,050 | 6-8 weeks | |
50 mg | $1,370 | 6-8 weeks | |
100 mg | $1,990 | 6-8 weeks |
Description | MK-8033 hydrochloride is an effective and orally active dual inhibitor of ATP competitive c-Met/Ron, with 1 nM for c-Met and 7nM for Ron IC50. MK-8033 hydrochloride has a high affinity for activated kinase conformation, and is suitable for the study of breast cancer, bladder cancer, and non-small cell lung cancer (NSCLC). |
Molecular Weight | 507.99 |
Formula | C25H22ClN5O3S |
Cas No. | 1283000-43-0 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: < 1 mg/mL (insoluble or slightly soluble) |
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