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N,O-Didansyl-L-tyrosine cyclohexylammonium

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Catalog No. T77237Cas No. 102783-47-1

N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].

N,O-Didansyl-L-tyrosine cyclohexylammonium

N,O-Didansyl-L-tyrosine cyclohexylammonium

😃Good
Catalog No. T77237Cas No. 102783-47-1
N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].
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Product Introduction

Bioactivity
Description
N,O-Didansyl-L-tyrosine cyclohexylammonium is a potent and selective inhibitor of thymidylate synthase (TS), showing activity against TS in Escherichia coli, Lactobacillus casei, and humans, with IC50 values of 5.0, 3.4, and 119 μM, respectively [1].
Chemical Properties
Molecular Weight746.94
FormulaC39H46N4O7S2
Cas No.102783-47-1
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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