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Perfluorooctanoic acid

Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.

Catalog No. T9333Cas No. 335-67-1

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Purity:100%

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COA FNMR LCMS

Perfluorooctanoic acid

Catalog No. T9333Cas No. 335-67-1

Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 mg	$50	In Stock
10 mg	$75	In Stock
25 mg	$128	In Stock
50 mg	$192	In Stock
100 mg	$287	In Stock
200 mg	$431	In Stock
500 mg	$713	In Stock
1 mL x 10 mM (in DMSO)	$74	In Stock

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Product Introduction

Bioactivity

Description	Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.
Targets&IC50	3β-HSD:53.2μM, 17β-HSD3: 17.7μM
In vitro	Perfluorooctanoic acid exposure impaired the tight junction of corneal cells and caused inflammatory reactions in the retina. Exposure of the cornea to perfluorooctanoic acid contained in particulate matter might induce oxidative stress and inflammation in the retina and represent a risk factor for age-related macular degeneration[1]. PFOA had toxic effects on SMMC-7721 cells, such as inhibiting cell proliferation and inducing apoptosis[2].
Alias	PFOA

Chemical Properties

Molecular Weight	414.07
Formula	C₈HF₁₅O₂
Cas No.	335-67-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 65 mg/ml (156.98 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4151 mL	12.0753 mL	24.1505 mL	120.7525 mL
5 mM	0.4830 mL	2.4151 mL	4.8301 mL	24.1505 mL
10 mM	0.2415 mL	1.2075 mL	2.4151 mL	12.0753 mL
20 mM	0.1208 mL	0.6038 mL	1.2075 mL	6.0376 mL
50 mM	0.0483 mL	0.2415 mL	0.4830 mL	2.4151 mL
100 mM	0.0242 mL	0.1208 mL	0.2415 mL	1.2075 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc