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Ursolic acid
🥰Excellent
Catalog No. T0722Cas No. 77-52-1
Alias Urson, Prunol, NSC-4060, NSC 167406, Malol
Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities.
Ursolic acid
🥰Excellent
Purity: 99.7%
Catalog No. T0722Alias Urson, Prunol, NSC-4060, NSC 167406, MalolCas No. 77-52-1
Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $42 | In Stock | |
| 100 mg | $50 | In Stock | |
| 200 mg | $83 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $46 | In Stock |
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Purity:99.7%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities. |
| In vitro | METHODS: Embryonal carcinoma cells NTERA-2 and NCCIT were treated with Ursolic acid (1-50 µM) for 24 h. Cell viability was measured by MTT assay. RESULTS: Concentration-dependent inhibition of NTERA-2 and NCCIT cell viability by Ursolic acid treatment. [1] METHODS: Lung cancer cells H460 and H1975 were treated with Ursolic acid (5-20 nM) for 48 h. Apoptosis was detected by Flow cytometry. RESULTS: Ursolic acid significantly increased the percentage of Annexin V (+) apoptotic cells compared to control. [2] |
| In vivo | METHODS: To investigate the antidepressant-like effects, Ursolic acid (0.001-10 mg/kg, distilled water with 10% Tween 80) was orally administered to Swiss mice, and the TST, FST, or open-field test was performed 60 min later. RESULTS: Ursolic acid shortened the immobilization time in TST and FST.The antidepressant-like effect of Ursolic acid in TST may be mediated by the activation of dopamine D1 and D2 receptors interacting with the dopaminergic system. [3] |
| Alias | Urson, Prunol, NSC-4060, NSC 167406, Malol |
| Molecular Weight | 456.7 |
| Formula | C30H48O3 |
| Cas No. | 77-52-1 |
| Smiles | C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |
| Relative Density. | 1.09 g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) Propylene glycol: 4.76 mg/ml (10.42 mM）, Sonification is recommended.  DMSO: 50 mg/mL (109.48 mM) Ethanol: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Propylene glycol/DMSO
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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