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Compound Libraries Target / Pathway Focused

Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No. product name
L2000 Inhibitor Library A unique collection of 3809 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; 3809 compounds
L2700 Adrenergic Receptor Compound Library A unique collection of 117 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; 117 compounds
L9000 Apoptosis Compound Library A unique collection of 733 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; 733 compounds
L3200 Autophagy Compound Library A unique collection of 623 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; 623 compounds
L2600 Neuronal Signaling Compound Library A unique collection of 936 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; 936 compounds
L1200 Epigenetics Compound Library Quantity: well-chosen 903 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; 903 compounds
L3300 Histamine & Melatonin Library A unique collection of 99 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; 99 compounds
L2300 Ion Channel Inhibitor Library A unique collection of 640 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; 640 compounds
L1400 MAPK Inhibitor Library A unique collection of 140 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; 140 compounds
L1300 PI3K-AKT-mTOR Compound Library A unique collection of 200 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; 200 compounds
L1100 Protease Inhibitor Library A unique collection of 295 protease and proteasome inhibitors for research in chemical genomics, and drug screening; 295 compounds
L2800 Serotonin Compound Library A unique collection of 134 compounds targeting serotonin receptors for high throughput screening and high content screening; 134 compounds
L2200 Tyrosine kinase inhibitor library A unique collection of 560 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; 560 compounds
L3900 DNA Damage & Repair Compound Library A unique collection of 475 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); 475 compounds
L3600 Cytokine Inhibitor Library A unique collection of 182 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; 182 compounds
L1600 Kinase Inhibitor Library A unique collection of 1339 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; 1339 compounds
L1500 GPCR Compound Library A unique collection of 1263 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; 1263 compounds
L5300 Mitochondrial Targeting Compound Library A unique collection of 168 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; 168 compounds
L4800 Angiogenesis related Compound Library A unique collection of 378 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); 378 compounds
L3700 JAK STAT Compound Library A unique collection of 145 JAK/STAT signaling targeted compounds for high throughput and high content screening; 145 compounds
L3800 NF-κB Signaling Compound Library A unique collection of 173 compounds targeting NF-κB signaling for high throughput screening and high content screening; 173 compounds
L4100 TGF-beta/Smad Compound Library A unique collection of 116 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; 116 compounds
L4300 Wnt&Hedgehog&Notch Compound Library A unique collection of 136 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; 136 compounds
L8100 Cell cycle related Compound Library A unique collection of 130 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); 130 compounds
L1510 Nuclear-receptor Inhibitors Library A unique collection of 239 nuclear receptor signaling targeted compounds for high throughput and high content screening; 239 compounds
L7200 Calcium Antagonists Library A unique collection of 48 calcium channel blockers and agonists for high throughput and high content screening; 48 compounds
L7300 Potassium Channel Blockers Library A unique collection of 60 potassium channel blockers and agonists for high throughput and high content screening; 60 compounds
L7400 Sodium Channel Blockers Library A unique collection of 62 sodium channel blockers and agonists for high throughput and high content screening; 62 compounds
L7600 Chemokine inhibitors Library A unique collection of 27 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; 27 compounds
L9100 Phosphatase Inhibitor Library A collection of 24 phosphatase inhibitors with known activity; 24 compounds
L1580 GPCR Library Plus Quantity: well-chosen 403 GPCR targeting compounds with unique structures; 403 compounds
L2610 Neurotransmitter Receptor Compound Library A unique collection of 400 neurotransmitter receptor compounds, can be used for HTS and HCS screening; 400 compounds
L8600 Ubiquitination Compound Library A unique collection of 78 ubiquitination related small chemicals can be used for high throughput and high content screening; 78 compounds
L8500 HIF-1 Signaling Pathway Compound Library A unique collection of 975 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; 975 compounds
L8700 Ferroptosis Compound Library A unique collection of 320 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; 320 compounds
Inhibitor Library
L2000 compounds - 3809
Adrenergic Receptor Compound Library
L2700 compounds - 117
Apoptosis Compound Library
L9000 compounds - 733
Autophagy Compound Library
L3200 compounds - 623
Neuronal Signaling Compound Library
L2600 compounds - 936
Epigenetics Compound Library
L1200 compounds - 903
Histamine & Melatonin Library
L3300 compounds - 99
Ion Channel Inhibitor Library
L2300 compounds - 640
MAPK Inhibitor Library
L1400 compounds - 140
PI3K-AKT-mTOR Compound Library
L1300 compounds - 200
Protease Inhibitor Library
L1100 compounds - 295
Serotonin Compound Library
L2800 compounds - 134
Tyrosine kinase inhibitor library
L2200 compounds - 560
DNA Damage & Repair Compound Library
L3900 compounds - 475
Cytokine Inhibitor Library
L3600 compounds - 182
Kinase Inhibitor Library
L1600 compounds - 1339
GPCR Compound Library
L1500 compounds - 1263
Mitochondrial Targeting Compound Library
L5300 compounds - 168
Angiogenesis related Compound Library
L4800 compounds - 378
JAK STAT Compound Library
L3700 compounds - 145
NF-κB Signaling Compound Library
L3800 compounds - 173
TGF-beta/Smad Compound Library
L4100 compounds - 116
Wnt&Hedgehog&Notch Compound Library
L4300 compounds - 136
Cell cycle related Compound Library
L8100 compounds - 130
Nuclear-receptor Inhibitors Library
L1510 compounds - 239
Calcium Antagonists Library
L7200 compounds - 48
Potassium Channel Blockers Library
L7300 compounds - 60
Sodium Channel Blockers Library
L7400 compounds - 62
Chemokine inhibitors Library
L7600 compounds - 27
Phosphatase Inhibitor Library
L9100 compounds - 24
GPCR Library Plus
L1580 compounds - 403
Neurotransmitter Receptor Compound Library
L2610 compounds - 400
Ubiquitination Compound Library
L8600 compounds - 78
HIF-1 Signaling Pathway Compound Library
L8500 compounds - 975
Ferroptosis Compound Library
L8700 compounds - 320