Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No.	product name
L2000	Inhibitor Library	A unique collection of 3809 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;	3809 compounds
L2700	Adrenergic Receptor Compound Library	A unique collection of 117 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification;	117 compounds
L9000	Apoptosis Compound Library	A unique collection of 733 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;	733 compounds
L3200	Autophagy Compound Library	A unique collection of 623 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs;	623 compounds
L2600	Neuronal Signaling Compound Library	A unique collection of 936 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;	936 compounds
L1200	Epigenetics Compound Library	Quantity: well-chosen 903 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;	903 compounds
L3300	Histamine & Melatonin Library	A unique collection of 99 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs;	99 compounds
L2300	Ion Channel Inhibitor Library	A unique collection of 640 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;	640 compounds
L1400	MAPK Inhibitor Library	A unique collection of 140 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;	140 compounds
L1300	PI3K-AKT-mTOR Compound Library	A unique collection of 200 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling;	200 compounds
L1100	Protease Inhibitor Library	A unique collection of 295 protease and proteasome inhibitors for research in chemical genomics, and drug screening;	295 compounds
L2800	Serotonin Compound Library	A unique collection of 134 compounds targeting serotonin receptors for high throughput screening and high content screening;	134 compounds
L2200	Tyrosine kinase inhibitor library	A unique collection of 560 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;	560 compounds
L3900	DNA Damage & Repair Compound Library	A unique collection of 475 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS);	475 compounds
L3600	Cytokine Inhibitor Library	A unique collection of 182 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery;	182 compounds
L1600	Kinase Inhibitor Library	A unique collection of 1339 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases;	1339 compounds
L1500	GPCR Compound Library	A unique collection of 1263 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research;	1263 compounds
L5300	Mitochondrial Targeting Compound Library	A unique collection of 168 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;	168 compounds
L4800	Angiogenesis related Compound Library	A unique collection of 378 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);	378 compounds
L3700	JAK STAT Compound Library	A unique collection of 145 JAK/STAT signaling targeted compounds for high throughput and high content screening;	145 compounds
L3800	NF-κB Signaling Compound Library	A unique collection of 173 compounds targeting NF-κB signaling for high throughput screening and high content screening;	173 compounds
L4100	TGF-beta/Smad Compound Library	A unique collection of 116 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;	116 compounds
L4300	Wnt&Hedgehog&Notch Compound Library	A unique collection of 136 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;	136 compounds
L8100	Cell cycle related Compound Library	A unique collection of 130 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS);	130 compounds
L1510	Nuclear-receptor Inhibitors Library	A unique collection of 239 nuclear receptor signaling targeted compounds for high throughput and high content screening;	239 compounds
L7200	Calcium Antagonists Library	A unique collection of 48 calcium channel blockers and agonists for high throughput and high content screening;	48 compounds
L7300	Potassium Channel Blockers Library	A unique collection of 60 potassium channel blockers and agonists for high throughput and high content screening;	60 compounds
L7400	Sodium Channel Blockers Library	A unique collection of 62 sodium channel blockers and agonists for high throughput and high content screening;	62 compounds
L7600	Chemokine inhibitors Library	A unique collection of 27 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;	27 compounds
L9100	Phosphatase Inhibitor Library	A collection of 24 phosphatase inhibitors with known activity;	24 compounds
L1580	GPCR Library Plus	Quantity: well-chosen 403 GPCR targeting compounds with unique structures;	403 compounds
L2610	Neurotransmitter Receptor Compound Library	A unique collection of 400 neurotransmitter receptor compounds, can be used for HTS and HCS screening；	400 compounds
L8600	Ubiquitination Compound Library	A unique collection of 78 ubiquitination related small chemicals can be used for high throughput and high content screening；	78 compounds
L8500	HIF-1 Signaling Pathway Compound Library	A unique collection of 975 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；	975 compounds
L8700	Ferroptosis Compound Library	A unique collection of 320 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；	320 compounds