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Characteristic Natural Product Libraries

Based on the number of genes, it has been estimated that the plant kingdom contains more than 200,000 different metabolites with values for single species ranging between 5,000 and 15,000, values that are significantly greater than those of microorganisms (∼1,500) and animals (∼2,500). We created several Characteristic Natural Product Libraries based on their biogenesis and the source they originate from (Alkaloids Natural Compound Library, Flavonoids Natural Compound Library, Polyphenolic Natural Compound Library, Terpene Natural Compound Library, Selected Plant-Sourced Compound Library, and Microbial Natural Product Library) as well as their specific applications (Anti-Inflammatory Traditional Chinese Medicine Library, Anti-Tumor Natural Products Library, and Food as Medicine Library).

Cat No. product name
L6160 RO5 Drug-like Natural Product Library 天然产物是先导化合物及候选药物的重要来源,其骨架结构复杂,官能团丰富,结构独特,多具有手性。这些自然形成的优势,为天然产物向药物的转化提供了更加多样的选择, 也是天然产物在药物开发与研究中发挥着重要作用的原因。 TargetMol应用类药性评价指标“Lipinski 五规则”,基于天然产物结构的多样性和新颖性,优选出符合RO5原则的2253个成药性良好的天然产物单体,涵盖萜类,生物碱类等多种结构类型,兼具生物活性和类药性,是新药发现、药物筛选和创新药物研究的有力工具。 2253 compounds
L6500 Microbial Natural Product Library 193种微生物来源的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; 193 compounds
L6800 Natural Compoud Library in Chinese Pharmacopoeia 2070种中国药典收录的天然产物,是药物开发、药理研究等领域的有力工具; 2070 compounds
L4600 Selected Plant-Sourced Compound Library 2720个植物来源天然产物的独特集合,来自277类植物的精心之选; 2720 compounds
L6140 Saccharide and Glycoside Natural Product Library 364种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选; 364 compounds
L6720 Anti-COVID-19 Traditional Chinese Medicine Compound Library 根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1162种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具; 1162 compounds
L6900 Rare Natural Compound Library 284种稀有天然产物的集合,可以用于高通量和高内涵筛选; 284 compounds
L6710 Anti-Inflammatory Traditional Chinese Medicine Compound Library 455种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具; 455 compounds
L6300 Food as Medicine Compound Library 910个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选; 910 compounds
L6150 Covalent Natural Product Library 提供产品的生物学信息和药物学信息,为筛选提供理论方向和研究基础; 596 compounds
L6110 Alkaloid Natural Product Library 317种生物碱类天然产物的独特集合,可用于高通量筛选和高内涵筛选; 317 compounds
L6700 Anti-Tumor Natural Product Library 1471种已知活性天然产物的独特集合,是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具,可用于HTS和HCS。 1471 compounds
L6600 Anti-Gastroenteritis Natural Product Library 223种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; 223 compounds
L6100 Polyphenolic Natural Product Library 411个天然多酚化合物的独特集合,可用于高通量、高内涵筛选; 411 compounds
L2500 Human Endogenous Metabolite Library 1400种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选; 1400 compounds
L6210 Tibetan medicine Compound Library 754种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; 754 compounds
L6810 Traditional Chinese Medicine Monomer Library 2390种中药来源的单体化合物,是药物开发、药理研究等领域的有力工具; 2390 compounds
L2540 Gut Microbial Metabolite Library 351种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; 351 compounds
L6130 Terpene Natural Product Library 349种萜类天然产物的独特集合,可用于高通量筛选和高内涵筛选; 349 compounds
L6120 Flavonoid Natural Product Library 252种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选; 252 compounds
RO5 Drug-like Natural Product Library
L6160 compounds - 2253
Microbial Natural Product Library
L6500 compounds - 193
Natural Compoud Library in Chinese Pharmacopoeia
L6800 compounds - 2070
Selected Plant-Sourced Compound Library
L4600 compounds - 2720
Saccharide and Glycoside Natural Product Library
L6140 compounds - 364
Anti-COVID-19 Traditional Chinese Medicine Compound Library
L6720 compounds - 1162
Rare Natural Compound Library
L6900 compounds - 284
Anti-Inflammatory Traditional Chinese Medicine Compound Library
L6710 compounds - 455
Food as Medicine Compound Library
L6300 compounds - 910
Covalent Natural Product Library
L6150 compounds - 596
Alkaloid Natural Product Library
L6110 compounds - 317
Anti-Tumor Natural Product Library
L6700 compounds - 1471
Anti-Gastroenteritis Natural Product Library
L6600 compounds - 223
Polyphenolic Natural Product Library
L6100 compounds - 411
Human Endogenous Metabolite Library
L2500 compounds - 1400
Tibetan medicine Compound Library
L6210 compounds - 754
Traditional Chinese Medicine Monomer Library
L6810 compounds - 2390
Gut Microbial Metabolite Library
L2540 compounds - 351
Terpene Natural Product Library
L6130 compounds - 349
Flavonoid Natural Product Library
L6120 compounds - 252