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Alkaloids

Alkaloids

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, produced by a large variety of organisms including bacteria, fungi, plants, and animals. Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine), and have been used in entheogenic rituals or as recreational drugs. Alkaloids can be toxic too (e.g. atropine, tubocurarine).

Cat No. Product Name
T0486L Irinotecan Hydrochloride Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active m...
T2714 Rotundine Rotundine is extracted from Corydalis yanhusuo W. T. Wang.
T3026 (-)-Huperzine A Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibi...
T2S1720 Huperzine B 1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates fo...
T8016 N-Benzylmethylamine N-Benzylmethylamine is an Alkaloids
TN1176 10-Nitro-camptothecin 10-Nitro-camptothecin is a natural product
T2718 Palmatine chloride Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
T0022 Taurine Taurine, an organic acid, is distributed in various animal tissues.
T3243 Betaine Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving bo...
T3021 Bulleyaconi cine A Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
T5061 Lumichrome Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at ...
T4S1869 12-Epinapelline 12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of...
T3232 Higenamine Hydrochloride
TN2325 (Z)-Akuammidine (Z)-Akuammidine is a natural product
TN1192 16-Epivoacarpine 16-Epivoacarpine is a natural product from Gelsemium elegans.
TN1746 Humantenidine Standard reference
T2726 Sinomenine Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
TQ0160 Hydrastine Hydrastine is a natural alkaloid that is present in Hydrastis Canadensis.
T0012 Cinchonine Cinchonine, a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local nar...
T1174 Topotecan hydrochloride Topotecan hydrochloride is an antineoplastic agent used to treat ovarian cancer.
T4S0051 Coptisine sulfate 1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
T5595 Tropine Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a v...
TN1752 Hydroxyevodiamine Hydroxyevodiamine is a natural product
T5784 Topotecan Topotecan is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
TN1026 Vomicine Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.
T4183 lavendustin A lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
T4036 Solasodine Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...
TJS1226 Aristolactam I A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc
TN1164 1-(3,4-Dimethoxycinnamoyl)piperidine 1-(3,4-Dimethoxycinnamoyl)piperidine is a natural product
T3S0128 Hydroprotopine Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
TN1627 Euojaponine D Euojaponine D is a natural product
TN2352 Pingpeimine C Pingpeimine C Derived from Fritillaria sibiricum.
TQ0192 Senecionine Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
T2S2362 Dehydrocorydaline nitrate 1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effec...
T5S0761 Nitidine chloride 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC...
T4S0794 (R)-(+)-Corypalmine 1. (R)-(+)-Corypalmine shows strong papaverine-like activity.
T0690 Quinine Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cra...
T7786 Tryptanthrin Tryptanthrin is a natural DNA gyrase inhibitor。
TN2203 Senecionine N-oxide Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.
T3S1227 Aristololactam I 1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I ma...
TN1925 Methyl anthranilate Methyl anthranilate is a natural product
T4S0536 Bullatine A 1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the trea...
T1156 Palonosetron hydrochloride Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
T5S0661 Koumine 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signi...
T5765 ranaconitine Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
T0486 Irinotecan hydrochloride trihydrate Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.
T8182 Guan-fu base A Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
T7056 Dronedarone Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
T4953 Neotuberostemonine Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM...
TN2206 Shancigusin I Shancigusin I is a natural from Cremastra appendiculata.
T1334 Hydroquinidine Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
T1668 Vinblastine sulfate Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
T2746 Sophocarpine Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
TCS2185 Yohimbine Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)
T2O2683 proline 1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline...
T0186 Docetaxel trihydrate Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the th...
T1231 Pilocarpine nitrate Pilocarpine nitrate is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
T7097 Cytochalasin B Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin).
T2183 Scopolamine butylbromide Scopolamine butylbromide is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).
TN2240 Strictosidinic acid Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
TN2370 6- Methoxydihydrosanguinarine 6-Methoxy Dihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxy Dihydrosanguinarine.
TN1099 Dihydroevocarpine Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is ...
TN1121 Evocarpine Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
T8161 Vicine Vicine, an alkaloid found in fava beans, is toxic in individuals and may cause haemolytic anaemia.
T4S0795 Berberrubine 1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in th...
T3S2340 Usaramine Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
T3S1457 Palmatrubine Palmatrubine shows high antitumor activity.
T1286 Vincamine Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cere...
TN2200 Segetalin A Segetalin A has estrogen-like activity.
T7939 Fingolimod Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
TN1749 Huperzine C Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.
TN1340 7beta-Hydroxyrutaecarpine 7beta-Hydroxyrutaecarpine is a natural product from Euodia ruticarpa.
T7026 KukoaMine B Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties.
TN1444 bis[6-(5,6-dihydrochelerythrinyl)]amine BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
T2754 Oxymatrine Oxymatrine is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis...
TN1129 Protostemotinine Protostemotinine is a natural product from Stemona japonica.
T8175 Laudanosine Laudanosine is a recognized metabolite of atracurium and cisatracurium.
T4116 Ademetionine S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinom...
TN1452 Broussonetine A Broussonetines A-H are glycosidase inhibitors.
TQ0258 Corynoxine B Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
TN1070 Aristolochic acid D Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxi...
T0970 Anisodamine Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
T6S0105 Peiminine 1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
TQ0264 Nigakinone Nigakinone, isolated from Kumu, is one alkaloid with the pharmacological activity.
T6S0033 Crotonoside 1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of th...
TN1353 (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide is a natural product
TJS0123 Arecoline Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (...
T8185 Viroallosecurinine (+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.
TN1393 (-)-Anonaine (-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DN...
T2S1200 Sinapine 1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant...
T6S2356 (+)-Corynoline 1. Corynoline is an acetylcholinesterase inhibitor.
T5S2357 Acetylcorynoline 1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of ...
TJS0312 7-hydroxy-4-methyl-8-nitrocoumarin
T3901 Solasonine Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.
T0086 Galanthamine HBr Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
T2764 10-Hydroxycamptothecin 10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
TN1346 8-Oxypalmatine 8-Oxypalmatine is a natural product
TN2023 Oxyepiberberine Oxyepiberberine is a natural product
TN1142 8-Oxycoptisine 8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
T5S0106 Peimisine 1. Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax ...
Irinotecan Hydrochloride
T0486LCAS 100286-90-6
Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active m...
Rotundine
T2714CAS 10097-84-4
Rotundine is extracted from Corydalis yanhusuo W. T. Wang.
(-)-Huperzine A
T3026CAS 102518-79-6
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibi...
Huperzine B
T2S1720CAS 103548-82-9
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates fo...
N-Benzylmethylamine
T8016CAS 103-67-3
N-Benzylmethylamine is an Alkaloids
10-Nitro-camptothecin
TN1176CAS 104195-61-1
10-Nitro-camptothecin is a natural product
Palmatine chloride
T2718CAS 10605-02-4
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
Taurine
T0022CAS 107-35-7
Taurine, an organic acid, is distributed in various animal tissues.
Betaine
T3243CAS 107-43-7
Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving bo...
Bulleyaconi cine A
T3021CAS 107668-79-1
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
Lumichrome
T5061CAS 1086-80-2
Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at ...
12-Epinapelline
T4S1869CAS 110064-71-6
12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of...
Higenamine Hydrochloride
T3232CAS 11041-94-4
(Z)-Akuammidine
TN2325CAS 113973-31-2
(Z)-Akuammidine is a natural product
16-Epivoacarpine
TN1192CAS 114027-38-2
16-Epivoacarpine is a natural product from Gelsemium elegans.
Humantenidine
TN1746CAS 114027-39-3
Standard reference
Sinomenine
T2726CAS 115-53-7
Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
Hydrastine
TQ0160CAS 118-08-1
Hydrastine is a natural alkaloid that is present in Hydrastis Canadensis.
Cinchonine
T0012CAS 118-10-5
Cinchonine, a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local nar...
Topotecan hydrochloride
T1174CAS 119413-54-6
Topotecan hydrochloride is an antineoplastic agent used to treat ovarian cancer.
Coptisine sulfate
T4S0051CAS 1198398-71-8
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
Tropine
T5595CAS 120-29-6
Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a v...
Hydroxyevodiamine
TN1752CAS 1238-43-3
Hydroxyevodiamine is a natural product
Topotecan
T5784CAS 123948-87-8
Topotecan is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
Vomicine
TN1026CAS 125-15-5
Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.
lavendustin A
T4183CAS 125697-92-9
lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
Solasodine
T4036CAS 126-17-0
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity agai...
Aristolactam I
TJS1226CAS 127191-86-0
A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc
1-(3,4-Dimethoxycinnamoyl)piperidine
TN1164CAS 128261-84-7
1-(3,4-Dimethoxycinnamoyl)piperidine is a natural product
Hydroprotopine
T3S0128CAS 128397-41-1
Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
Euojaponine D
TN1627CAS 128397-42-2
Euojaponine D is a natural product
Pingpeimine C
TN2352CAS 128585-96-6
Pingpeimine C Derived from Fritillaria sibiricum.
Senecionine
TQ0192CAS 130-01-8
Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
Dehydrocorydaline nitrate
T2S2362CAS 13005-09-9
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effec...
Nitidine chloride
T5S0761CAS 13063-04-2
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC...
(R)-(+)-Corypalmine
T4S0794CAS 13063-54-2
1. (R)-(+)-Corypalmine shows strong papaverine-like activity.
Quinine
T0690CAS 130-95-0
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cra...
Tryptanthrin
T7786CAS 13220-57-0
Tryptanthrin is a natural DNA gyrase inhibitor。
Senecionine N-oxide
TN2203CAS 13268-67-2
Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.
Aristololactam I
T3S1227CAS 13395-02-3
1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I ma...
Methyl anthranilate
TN1925CAS 134-20-3
Methyl anthranilate is a natural product
Bullatine A
T4S0536CAS 1354-84-3
1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the trea...
Palonosetron hydrochloride
T1156CAS 135729-62-3
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
Koumine
T5S0661CAS 1358-76-5
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signi...
ranaconitine
T5765CAS 1360-76-5
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
Irinotecan hydrochloride trihydrate
T0486CAS 136572-09-3
Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.
Guan-fu base A
T8182CAS 1394-48-5
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
Dronedarone
T7056CAS 141626-36-0
Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
Neotuberostemonine
T4953CAS 143120-46-1
Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM...
Shancigusin I
TN2206CAS 1435488-35-9
Shancigusin I is a natural from Cremastra appendiculata.
Hydroquinidine
T1334CAS 1435-55-8
Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
Vinblastine sulfate
T1668CAS 143-67-9
Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
Sophocarpine
T2746CAS 145572-44-7
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
Yohimbine
TCS2185CAS 146-48-5
Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)
proline
T2O2683CAS 147-85-3
1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline...
Docetaxel trihydrate
T0186CAS 148408-66-6
Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the th...
Pilocarpine nitrate
T1231CAS 148-72-1
Pilocarpine nitrate is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
Cytochalasin B
T7097CAS 14930-96-2
Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin).
Scopolamine butylbromide
T2183CAS 149-64-4
Scopolamine butylbromide is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).
Strictosidinic acid
TN2240CAS 150148-81-5
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
6- Methoxydihydrosanguinarine
TN2370CAS 151890-26-5
6-Methoxy Dihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxy Dihydrosanguinarine.
Dihydroevocarpine
TN1099CAS 15266-35-0
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is ...
Evocarpine
TN1121CAS 15266-38-3
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
Vicine
T8161CAS 152-93-2
Vicine, an alkaloid found in fava beans, is toxic in individuals and may cause haemolytic anaemia.
Berberrubine
T4S0795CAS 15401-69-1
1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in th...
Usaramine
T3S2340CAS 15503-87-4
Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
Palmatrubine
T3S1457CAS 16176-68-4
Palmatrubine shows high antitumor activity.
Vincamine
T1286CAS 1617-90-9
Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cere...
Segetalin A
TN2200CAS 161875-97-4
Segetalin A has estrogen-like activity.
Fingolimod
T7939CAS 162359-55-9
Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
Huperzine C
TN1749CAS 163089-71-2
Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.
7beta-Hydroxyrutaecarpine
TN1340CAS 163815-35-8
7beta-Hydroxyrutaecarpine is a natural product from Euodia ruticarpa.
KukoaMine B
T7026CAS 164991-67-7
Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties.
bis[6-(5,6-dihydrochelerythrinyl)]amine
TN1444CAS 165393-48-6
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
Oxymatrine
T2754CAS 16837-52-8
Oxymatrine is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis...
Protostemotinine
TN1129CAS 169534-85-4
Protostemotinine is a natural product from Stemona japonica.
Laudanosine
T8175CAS 1699-51-0
Laudanosine is a recognized metabolite of atracurium and cisatracurium.
Ademetionine
T4116CAS 17176-17-9
S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinom...
Broussonetine A
TN1452CAS 173220-07-0
Broussonetines A-H are glycosidase inhibitors.
Corynoxine B
TQ0258CAS 17391-18-3
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
Aristolochic acid D
TN1070CAS 17413-38-6
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxi...
Anisodamine
T0970CAS 17659-49-3
Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
Peiminine
T6S0105CAS 18059-10-4
1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
Nigakinone
TQ0264CAS 18110-86-6
Nigakinone, isolated from Kumu, is one alkaloid with the pharmacological activity.
Crotonoside
T6S0033CAS 1818-71-9
1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of th...
(9Z,12Z)-N-Benzyloctadeca-9,12-dienamide
TN1353CAS 18286-71-0
(9Z,12Z)-N-Benzyloctadeca-9,12-dienamide is a natural product
Arecoline
TJS0123CAS 18513-76-3
Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (...
Viroallosecurinine
T8185CAS 1857-30-3
(+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.
(-)-Anonaine
TN1393CAS 1862-41-5
(-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DN...
Sinapine
T2S1200CAS 18696-26-9
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant...
(+)-Corynoline
T6S2356CAS 18797-79-0
1. Corynoline is an acetylcholinesterase inhibitor.
Acetylcorynoline
T5S2357CAS 18797-80-3
1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of ...
7-hydroxy-4-methyl-8-nitrocoumarin
TJS0312CAS 19037-69-5
Solasonine
T3901CAS 19121-58-5
Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.
Galanthamine HBr
T0086CAS 1953-04-4
Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
10-Hydroxycamptothecin
T2764CAS 19685-09-7
10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
8-Oxypalmatine
TN1346CAS 19716-59-7
8-Oxypalmatine is a natural product
Oxyepiberberine
TN2023CAS 19716-60-0
Oxyepiberberine is a natural product
8-Oxycoptisine
TN1142CAS 19716-61-1
8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
Peimisine
T5S0106CAS 19773-24-1
1. Peimisine can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax ...
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