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Ligand for E3 Ligase

Ligand for E3 Ligase

Cat No. product name
T13141 Thalidomide D4 Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
T5334 VL285 VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
T4207 Protein degrader 1 hydrochloride Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
T18613 MV-1-NH-Me MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].
TQ0121 VH-298 VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α prot...
T18831 Thalidomide-propargyl Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for...
T13876 (S,R,S)-AHPC-propargyl (S,R,S)-AHPC-propargyl is a VHL ligand which is used in “click reaction” for PROTACs.
T13877 (S,S,S)-AHPC hydrochloride (S,S,S)-AHPC hydrochloride is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the ...
T13104 TD-106 TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.
T18612 Bestatin-amido-Me Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].
T0213 Thalidomide Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic...
Thalidomide D4
T13141CAS 1219177-18-0
Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.
VL285
T5334CAS 1448188-57-5
VL285 is a potent VHL ligand, degrading HaloTag7 fusion proteins.
Protein degrader 1 hydrochloride
T4207CAS 1448189-80-7
Protein degrader 1 hydrochloride is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs).
MV-1-NH-Me
T18613CAS 2095244-62-3
MV-1-NH-Me, the MV-1 based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].
VH-298
TQ0121CAS 2097381-85-4
VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α prot...
Thalidomide-propargyl
T18831CAS 2098487-39-7
Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-propargyl can be connected to the ligand for...
(S,R,S)-AHPC-propargyl
T13876CAS 2098799-78-9
(S,R,S)-AHPC-propargyl is a VHL ligand which is used in “click reaction” for PROTACs.
(S,S,S)-AHPC hydrochloride
T13877CAS 2115897-23-7
(S,S,S)-AHPC hydrochloride is a VHL amino building block, is a ligand used as a negative control for (S,R,S)-AHPC. It is the VH032-based VHL ligand used in the ...
TD-106
T13104CAS 2250288-69-6
TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.
Bestatin-amido-Me
T18612CAS 339186-54-8
Bestatin-amido-Me, the Bestatin-based IAP ligand, binds to ABL inhibitor via a linker to form SNIPER[1].
Thalidomide
T0213CAS 50-35-1
Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic...