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Home > Gamma-secretase
Cat.No. Product Name Information Area
T6935 PF-03084014 PF-03084014 (PF-3084014) is a specific γ-secretase inhibitor (IC50: 6.2 nM, in a cell... Others
T6870 L-685,458 L-685,458 is a specific and potent inhibitor of A beta PP gamma-secretase activity wi... Others
T6861 IMR-1 IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation w... Others
T6249 Avagacestat Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhi... Cancer
T6202 DAPT DAPT (GSI-IX) is a novel γ-secretase inhibitor, which reduces the Aβ production with ... Cancer
T6135 Dibenzazepine YO-01027 is a potent γ-secretase inhibitor. Others
T6125 Semagacestat Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/... Cancer
T6063 LY411575 LY411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane an... Others
T3075 FLI-06 FLI-06 is a Notch signaling inhibitor (EC50: 2.3 μM). Cancer
T2639 LY2811376 LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-2... Nervous system
T2625 MK0752 MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM). Nervous system
T2262 CHF5074 CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM). Other
T6274 RO4929097 RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40... Cancer