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mTOR

Cat.No.	Product Name	Information	Area
T4639	MSDC 0602	MSDC-0602 is an insulin sensitizer potentially for the treatment of diabetes.	Non-alcoholic steatohepatitis
T4423	LY303511 hydrochloride	LY303511 (NV-128)is a potent mTOR inhibitor
T3514	CZ415	CZ415 is a potent and highly selective mTOR inhibitor.
T3692	GNE 477	GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.	Others
T3351	CC-223	CC-223 is an orally available mTOR inhibitor with potential antitumor activity. CC-22...	Cancer
T3656	PKI-402	PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with ...	Others
T3153	Serabelisib	MLN1117 (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).	Cancer
T3395	Timosaponin AIIInew	Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC...
T6510	GDC-0349	GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 n...	Cancer
T6732	WYE-687	WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; bloc...	Cancer
T6730	WAY-600	WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n...	Cancer
T6731	WYE-354	WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It ...	Cancer
T6100	Torin 2	Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold great...	Cancer
T6045	Torin 1	Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold ...	Cancer
T6033	Zotarolimus	Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).	Cancer
T6030	XL388	XL388 is a highly effective, specifc, ATP-competitive inhibitor of mTOR ( IC50: 9.9 ...	Cancer
T2995	Chrysophanic Acid	Chrysophanic acid is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, a...	Cancer
T2706	Palomid 529	Palomid 529 has been used in trials studying the treatment of Age-Related Macular Deg...	Cancer
T2619	CH5132799	CH5132799 has been used in trials studying the treatment of Solid Tumors.	Cancer
T2475	KU0063794	KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.	Other
T2434	LY 303511	LY303511, an inactive analogue of LY294002, is a mTOR inhibitor and no inhibition for...	Other
T2415	PP121	PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (I...	Cancer
T2414	Torkinib	PP 242 is a specific and ATP competitive mTOR inhibitor (IC50=8 nM).	Other
T2357	GSK-1059615	GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours,...	Cancer
T2235	Dactolisibhot	Dactolisib is an orally bioavailable imidazoquinoline targeting the phosphatidylin...	Cancer
T2145	Temsirolimus	Temsirolimus is a specific mTOR inhibitor, used in the treatment of advanced renal ce...	Immunology
T2144	Tacrolimus	Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces...	Immunology
T2084	ETP46464	ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).	Other
T1970	Gedatolisib	Gedatolisib is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4...	Other
T1961	Vistusertib	AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTO...	Other

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