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Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.30 kDa and the accession number is Q9NYJ7-1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $581 | 7-10 days | |
500 μg | $2,330 | 7-10 days | |
1 mg | $3,880 | 7-10 days |
Biological Activity | Immobilized Human DLL3 (27-215) , His Tag at 0.2μg/ml (100μl/Well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. |
Description | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). DLL3 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 22.30 kDa and the accession number is Q9NYJ7-1. |
Species | Human |
Expression System | HEK293 Cells |
Tag | N-His-Flag |
Accession Number | Q9NYJ7-1 |
Synonyms | δ3,SCDO1δ3,SCDO1delta3,SCDO1,Pudgy,DLL3,Delta3 |
Construction | Ala27-Glu215 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | 22.30 kDa (predicted). Due to glycosylation, the protein migrates to 24-25 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in PBS, 360 mM NaCl, 200 mM L-arginine (pH 8.0). |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | Shipping with blue ice. |
Research Background | Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity). |
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