[d-phe12,leu14]-bombesin

Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.

[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.

(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH (TFA)) (For-Nle-Leu-Phe-Nle-Tyr-Lys-OH TFA) is a formyl peptide receptor (FPR) agonist[1].Potent chemoattractant for human neutrophils.Radioiodinated molecule has full biological activity.

H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride), a chromogenic substrate, mimics the N-terminal fragment of the A alpha chain of fibrinogen, the native substrate of thrombin. Specifically designed for thrombin detection, H-D-Phe-Pip-Arg-pNA dihydrochloride is employed for the quantification of antithrombin-heparin cofactor (AT-III). The AT-III assay utilizing this substrate is characterized by its sensitivity, accuracy, and ease of implementation.

N-Formyl-Met-Leu-Phe-Lys (fMLFK) (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.

[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.

N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).

Bombesin receptor antagonist

Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) of 1.5 µM, 2.3 µM, and 40.5 µM for branched-chain amino acid-preferred, small neutral amino acid-preferred, and chymotrypsin-like activities, respectively, and an inhibitory concentration (IC50) of 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity [1].

Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor with antitumor properties, utilized in the research of acute myeloid leukemia [1].

[D-Ala2] Leu-Enkephalinamide, an enkephalin analog, exhibits significant corneal permeability and analgesic properties, making it suitable for ocular disease research [1] [2].

D-Val-Leu-Lys-chloromethylketone, a tripeptide, functions as an anticoagulant [1].

S 2238 is a chromogenic substrate for thrombin that is used in amidolytic assay.

(D-Trp8,D-Cys14)-Somatostatin-14, a synthetic analogue of somatostatin, is utilized in the study of metabolic-related diseases [1] [2].

[D-Trp8] Somatostatin-14 is a potent tetradecapeptide analog of native somatostatin, exhibiting increased efficacy [1].

Boc-D-Phe(3-F)-OH is a useful organic compound for research related to life sciences. The catalog number is T65692 and the CAS number is 114873-11-9.

Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl is an HIV-1 inhibitor that functions by interacting with gp120, thereby preventing its binding to CD4. This mechanism helps to maintain CD4-dependent T cell function.

'(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) is a somatostatin analogue exhibiting varying affinity for somatostatin receptors, with dissociation constants (Kd) of 0.61 nM for SSTR5, 11.05 nM for SSTR3, 23.5 nM for SSTR2, 1200 nM for SSTR1, and >1000 nM for SSTR4, respectively [1].'

H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH is a water-soluble polypeptide capable of acting as a substrate for enzymes cathepsin D, pepsin, and pepsinogen, holding potential applications in biochemical analysis [1] [2].

Z-D-Leu-OH is a useful organic compound for research related to life sciences. The catalog number is T65908 and the CAS number is 28862-79-5.

Boc-D-Leu-OMe is a useful organic compound for research related to life sciences. The catalog number is T67216 and the CAS number is 133467-01-3.

H-D-Phe-OtBu.HCl is an amino acid derivative and has a wide range of applications in life science related research.

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.

N-Formyl-Nle-Leu-Phe-Nle-Tyr-Lys TFA is a formyl peptide receptor (FPR) agonist.

{Boc}-Phe-Leu-Phe-Leu-Phe ({Boc}-FLFLF) is a selective antagonist of the formyl peptide receptor (FPR) family, effectively inhibiting receptor activity in response to formyl peptides.

Tyr-(D-Dab4,Arg5,D-Trp8)-cyclo-Somatostatin-14 (4-11) is a somatostatin agonist utilized in cancer research [1].

Fmoc-D-Phe-OH is an amino acid derivative and has a wide range of applications in life science related research.

H-D-Leu-NH2.HCl is an amino acid derivative and has a wide range of applications in life science related research.

Boc-D-Phe(4-Br)-OH is an amino acid derivative and has a wide range of applications in life science related research.

H-D-Phe-Pip-Arg-pNA (S-2238) acetate is a chromogenic substrate designed based on the N-terminal fragment of the A alpha chain of fibrinogen, which is the physiological target of thrombin. As a specific indicator of thrombin activity, H-D-Phe-Pip-Arg-pNA acetate is utilized to quantify. This assay, utilizing H-D-Phe-Pip-Arg-pNA acetate, ensures high sensitivity, accuracy, and ease of execution.

Boc-D-Phe(3,4-DiF)-OH is an amino acid derivative and has a wide range of applications in life science related research.

Fmoc-D-Phe(4-I)-OH is an amino acid derivative and has a wide range of applications in life science related research.

Fmoc-D-Phe(3-F)-OH is a useful organic compound for research related to life sciences. The catalog number is T65834 and the CAS number is 198545-72-1.

D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation [1].

Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH2 is a synthetic cyclic octapeptide that exhibits melanocortin-4 receptor (MC4R) agonism and has been shown to significantly elevate heart rate and blood pressure [1].

Boc-D-Leu-OH is a useful organic compound for research related to life sciences. The catalog number is T66581 and the CAS number is 16937-99-8.

Fmoc-D-Phe(2-F)-OH is an amino acid derivative and has a wide range of applications in life science related research.

[D-Leu-4]-OB3 suppresses the expression of genes associated with inflammation, proliferation, and metastasis, as well as the expression of PD-L1. Additionally, it promotes the expression of genes that induce apoptosis [1].

E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioid receptor (KOR) agonist [1].

Boc-D-Phe(3,4-Cl2)-OH is an amino acid derivative and has a wide range of applications in life science related research.

H-D-Phe(3-F)-OH is a useful organic compound for research related to life sciences. The catalog number is T67306 and the CAS number is 110117-84-5.

Fmoc-D-Phe(4-F)-OH is an amino acid derivative and has a wide range of applications in life science related research.

H-D-Phe(4-CN)-OH is a useful organic compound for research related to life sciences. The catalog number is T65897 and the CAS number is 263396-44-7.

Fmoc-D-Phe(2-Cl)-OH is an amino acid derivative and has a wide range of applications in life science related research.

Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.

Fmoc-D-Phe(3,4-DiCl)-OH is an amino acid derivative and has a wide range of applications in life science related research.

N-Boc-Phe-Leu-Phe-Leu-Phe (Boc-FLFLF) (Boc-FLFLF) is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin. Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research.

Suc-Ala-Leu-Pro-Phe-pNA (Suc-ALPF-pNA), a substrate for FK-506 binding protein (FKBP) [1], showcases the intricate interactions necessary for specific biochemical assays.

(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].