T21685 |
CCT 031374 hydrobromide
|
|
Wnt/beta-catenin
|
|
CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities. |
T6113 |
ICG-001
|
|
Epigenetic Reader Domain
,
Apoptosis
,
Wnt/beta-catenin
|
|
ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) wit... |
T9988 |
WAY-328173
|
|
Wnt/beta-catenin
|
|
WAY-328173 is a Wnt/beta-catenin agonist. |
TP1263 |
Fz7-21
|
(Ac)-LPSDDLEFWCHVMY-NH2 |
Wnt/beta-catenin
|
|
Fz7-21 is a peptide antagonist of FZD7 . It antagonises WNT3A-induced Wnt-β-catenin signalling in HEK293 expressing FZD7... |
T4022 |
QS11
|
QS 11 |
GTPase
|
|
QS 11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and syne... |
T3925 |
Astragaloside I
|
Cyclosieversioside B , Astrasieversianin IV |
Wnt/beta-catenin
|
|
Astragaloside I is a natural product isolated from Astragalus. |
T9500 |
M435-1279
|
|
E1/E2/E3 Enzyme
|
|
M435-1279 is a UBE2T inhibitor. M435-1279 blocks UBE2T-mediated degradation of RACK1, leading to inhibit the hyperactiva... |
TN1103 |
Diphyllin
|
|
ATPase
,
Influenza Virus
,
Proton pump
,
HIV Protease
|
|
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylati... |
TL0007 |
Bisdemethoxycurcumin
|
Didemethoxycurcumin , Curcumin III |
Wnt/beta-catenin
,
Epigenetic Reader Domain
|
|
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagoc... |
T5S1058 |
Triptonide
|
PG 492 , NSC 165677 |
Apoptosis
,
Wnt/beta-catenin
,
Autophagy
|
|
1. Triptonide is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities.... |
T8005 |
Cardiogenol C hydrochloride
|
Cardiogenol C , Cardiogenol C HCl |
Wnt/beta-catenin
|
|
Cardiogenol C hydrochloride can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM). |
T39200 |
β-catenin-IN-37
|
|
|
|
β-catenin-IN-37 is a selective β-Catenin/T-cell factor protein-protein interaction (β-catenin/Tcf PPI) inhibitor. β-cate... |
T60803 |
Wnt/β-catenin agonist 4
|
|
|
|
Wnt/β-catenin agonist 4 (Derivative 83) activates the transmission of Wnt/β-catenin signal that is a Wnt agonist [1]. |
T40256 |
ZW4864
|
|
|
|
ZW4864 is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) ... |
T36275 |
XStAx-VHLL
|
|
|
|
Selective peptide-based β-catenin Degrader. Comprises a β-catenin-targeted stapled peptide, xStAx, linked to a VHL-bindi... |
T28135 |
NC043
|
NC 043 , NC-043 |
|
|
NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF. |
T9662 |
SRI 37892
|
|
Wnt/beta-catenin
|
|
SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability. |
TP1979 |
NLS-StAx-h
|
|
|
|
Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription fa... |
T40643 |
Prodigiosin hydrochloride
|
Prodigiosine hydrochloride |
|
|
Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prod... |
T21735 |
NNGH
|
|
|
|
NNGH is a stromelysin-1 ( MMP-3 ) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor o... |