T11075 |
Donitriptan
|
|
5-HT Receptor
|
|
Donitriptan is a 5-HT receptor agonist with pKis of 9.4 and 9.3 for 5-HT1B and 5-HT1D, respectively. |
T37015 |
Iprindole
|
|
5-HT Receptor
|
|
Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1]. |
T2209 |
Serotonin hydrochloride
|
5-HT HCl,5-Hydroxytryptamine hydrochloride,5-HT hydrochloride,Serotonin HCl |
Endogenous Metabolite
,
5-HT Receptor
,
Transferase
|
|
Serotonin hydrochloride is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol ... |
T10169 |
5-HT4 antagonist 1
|
|
5-HT Receptor
|
|
5-HT4 antagonist 1 is an antagonist of 5-HT4 (pKi = 9.6). |
T8666 |
Naratriptan
|
|
5-HT Receptor
|
|
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches. |
T14490 |
Talipexole dihydrochloride
|
Domnin,B-HT 920 dihydrochloride |
Adrenergic Receptor
,
5-HT Receptor
,
Dopamine Receptor
|
|
Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-H... |
T11720 |
JNJ-18038683
|
|
5-HT Receptor
|
|
JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT... |
T2459 |
BRL 54443
|
BRL54443 |
5-HT Receptor
|
|
BRL 54443 is a potent 5-HT1E/1F receptor agonist (pKi values are 8.7 and 8.9 respectively). |
T5387 |
LP-211
|
|
5-HT Receptor
,
Dopamine Receptor
|
|
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-H... |
T2815 |
Puerarin
|
Kakonein |
5-HT Receptor
|
|
Puerarin, also known as Kakonein, is a member of the class of compounds known as isoflavonoid C-glycosides. It is a 5-HT... |
TN2437 |
Serotonin
|
5-hydroxytryptamine,5-HT |
Endogenous Metabolite
,
Transferase
,
5-HT Receptor
,
Others
|
|
5-hydroxytryptamine is a natural product from animals |
T8441 |
Lerisetron
|
|
5-HT Receptor
|
|
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. |
T17033 |
Temanogrel
|
APD791 |
5-HT Receptor
|
|
Temanogrel is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM). |
T3179 |
Eptapirone
|
F 11440 |
5-HT Receptor
|
|
F 11440 is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential. |
T9113 |
Myristicin
|
Myristicine |
P450
,
Caspase
,
5-HT Receptor
,
BCL
,
GABA Receptor
,
NO Synthase
,
PARP
,
Anti-infection
,
IL Receptor
|
|
Myristicin is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial... |
T12847 |
SB-616234-A
|
SB-616234A |
5-HT Receptor
|
|
SB-616234A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant acti... |
T10075 |
2-Methyl-5-HT
|
2-Methyl-5-hydroxytryptamine |
5-HT Receptor
|
|
2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like ... |
T5336 |
Zacopride hydrochloride
|
|
5-HT Receptor
,
Potassium Channel
|
|
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also ... |
T4305 |
8-OH-Dpat
|
8-Hydroxy-DPAT |
5-HT Receptor
|
|
8-OH-Dpat is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin. |
T0525 |
Flopropione
|
Phloropropiophenone |
5-HT Receptor
,
Transferase
|
|
Flopropione, a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist. |