Search Result

Search Results for " amyloid-β "

Targets

221

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
TP1214L	β-Amyloid 15-21 acetate	Beta-Amyloid (15-21) acetate	Beta Amyloid
	β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.		Beta Amyloid
TP1229	β-Amyloid (1-15)	Amyloid β-Protein (1-15)	Beta Amyloid
	β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.		Beta Amyloid
T7562	β-Amyloid (31-35)	β-Amyloid 31-35(TFA),β-Amyloid 31-35	Beta Amyloid
	β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.		Beta Amyloid
T14284	β-Amyloid (25-35)	β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35)	Beta Amyloid
	β-Amyloid (25-35) (Aβ25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic activities in cultured cells.		Beta Amyloid
TP1786L	Amyloid β-Protein 10-20 acetate	Amyloid β-Protein 10-20 acetate(152286-31-2 free base)	Beta Amyloid
	Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α...		Beta Amyloid
T35499	β-Amyloid (1-42), (rat/mouse) (TFA)	Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA
	β-Amyloid (1-42), (rat/mouse) (TFA) is a peptide fragment consisting of 42 amino acids that can be used to study Alzheimer's disease.
TP1866L	β-amyloid 1-11 acetate(190436-05-6 free base)		Beta Amyloid
	β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.		Beta Amyloid
TP1007L	β-Amyloid (1-42), acetate (human)	β-Amyloid (1-42), human acetate (107761-42-2 Free base)
	β-Amyloid (1-42), acetate (human) is a peptide consisting of 42 amino acids that is part of β-Amyloid and is commonly used in Alzheimer's disease modeling.
TP1359L	Amyloid β Peptide (42-1)(human) acetate	Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)	Beta Amyloid
	Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid β Peptide (42-1)(human) acetate is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease...		Beta Amyloid
T37768	β-Amyloid (1-37) (human)
	β-Amyloid (1-37) (human) Potentially associated with mental status in Alzheimer's disease.
T38149	β-Amyloid (1-43)(human)
	The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor ...
T37368	Amyloid-β (1-8) Peptide
	Amyloid-β (1-8) is a wild-type control for the mutation-containing amyloid-β (1-8, A2V) peptide .
T39285	Biotin-β-Amyloid (1-40)
	Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid- -(1-40) peptide.
T35498	β-Amyloid (1-14),mouse,rat
	β-Amyloid (1-14),mouse,rat is a 1 to 14 fragment of Amyloid-β peptide. β-Amyloid (1-14),mouse,rat is produced through the proteolytic processing of a transmembrane protein, amyloid precursor protein (APP), by β- and γ-se...
T39302	β-Amyloid (1-38), mouse, rat
	β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide. Notably, it serves as the primary constituent of amyloid plaques associated wi...
T37369	Amyloid-β (1-8, A2V) Peptide	Amyloid-β (1-8, A2V) Peptide
	Amyloid-β (1-8, A2V) is a truncated form of amyloid-β (Aβ) that contains a valine to alanine substitution at position 2 of the Aβ numbering convention (Aβ A2V), which corresponds to position 673 of the amyloid precursor ...
TP1226	β-Amyloid (1-28)	Amyloid β-Protein (1-28),β-Amyloid 1-28
	β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
T39146	β-Amyloid (1-40), FAM-labeled
	β-Amyloid (1-40), FAM-labeled, is a β-Amyloid (1-40) peptide tagged with a FAM fluorescent label, exhibiting an excitation wavelength (λ ex) of 492 nm and an emission wavelength (λ em) of 518 nm.
TP1303	β-Amyloid (1-40)	β-Amyloid 1-40
	Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.
TP1692	β-Amyloid (13-27)	β-Amyloid 13-27
	β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein. This synthetic peptide consists of amino acids 26 to 40 of beta amyloid protein. It can be used to study the kinetics of beta a...
TP1500	β-Amyloid (1-17)	β-Amyloid 1-17
	This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
TP1494	β-Amyloid (4-10)	β-Amyloid 4-10
	Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.
TP1538	β-Amyloid (1-20)	β-Amyloid 1-20
	This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
TP1231	β-Amyloid (29-40)	Amyloid beta-protein(29-40),β-Amyloid 29-40
	β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties related to those of fusion peptides of viral proteins. The fusio...
TP1228	β-Amyloid (1-16)	Amyloid β-Protein (1-16),β-Amyloid 1-16
	β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid. It exhibits the ability to bind to metal ions, indicating its involvement in metal-binding processes. β-Amyloid, a peptide, is...
TP1225	β-Amyloid (22-35)	β-Amyloid 22-35,Amyloid β-Protein (22-35)
	β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells. Beta amyloid (22-35) is a synthetic truncated fragment of beta-amyloid peptide.
TP1786	β-Amyloid (10-20)	Amyloid β-Protein 10-20
	Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-secretase processing site (Lys16-Leu17 bond). It also contains ...
TP1719	β-Amyloid (33-40)	β-Amyloid 33-40
	β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.
TP1586	β-Amyloid (35-42)	β-Amyloid 35-42
	β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.
TP1866	β-Amyloid (1-11)	β-amyloid 1-11
	Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.
TP1544	β-Amyloid (22-40)	β-Amyloid 22-40
	This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein. This peptide sequence is often used in beta amyloid structure and aggregation studies.
TP1645	β-Amyloid (1-9)	β-Amyloid 1-9
	This is an N-terminal fragment of beta amyloid. It consists of amino acid residues 1 to 9. Truncated beta amyloid peptide (10-40) still forms amyloid fibrils and shows fibril polymorphism.
TP1227	β-Amyloid (12-28)	β-amyloid 12-28,Amyloid β-Protein (12-28)
	Amyloid β-peptide fragment; minimum section required to bind to brain proteins. Binds with high affinity to α7-nicotinic ACh receptors, and impairs memory retention following central administration in mice in vivo.
TP1673	β-Amyloid (11-22)	β-Amyloid 11-22
	β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be the cause of Alzheimer’s Disease (AD). A...
T37367	Amyloid-β (1-42) Peptide (trifluoroacetate salt)
	Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-amino acid protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's disease.1,2,3Aggregation of Aβ42 results in the formation of ne...
TP1480	β-Amyloid (12-20)	β-Amyloid 12-20
	β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has amnestic effects.
TP1599	β-Amyloid (1-34)	β-Amyloid 1-34
	This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
TP1633	β-Amyloid (18-28)	β-Amyloid 18-28
	Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice. These peptides have only amino acid residues VFF at position 18 to 20 in common, suggesting ...
T37472	TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
	TAMRA-Amyloid-β (1-42) peptide is a fluorescently labeled peptide. Amyloid-β (1-42) (Aβ42) is a neurotoxic 42-residue protein fragment found in amyloid plaques in postmortem cerebral cortex from patients with Alzheimer's...
T21890	JLK6		Gamma-secretase
	JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signalling		Gamma-secretase
T37370	Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
	Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red an...
TP1214	β-Amyloid 15-21	Beta-Amyloid (15-21)
	β-amyloid (15-21) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease. This fragment is involved in beta sheet formation.
TP1007	β-Amyloid (1-42), human	β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human	Beta Amyloid
	Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.		Beta Amyloid
T80037	5-FAM-β-Amyloid (1-28)	5-FAM-Amyloid β-protein (1-28)
	5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.
T37200	Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)
	Biotin-amyloid-β (1-42) peptide is an affinity probe that allows amyloid-β (1-42) (Aβ42) to be detected or immobilized through interaction with the biotin ligand. It has been used to identify Aβ42 interaction partners in...
TP1359	β-Amyloid (42-1), human	Amyloid β Peptide (42-1)(human)
	Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
TP1441	β-Amyloid (1-40) (rat)	Amyloid β-peptide (1-40) rat
	Rat form of the beta-Amyloid (1-40) peptide
T80035	Biotin-β-Amyloid (1-42), human TFA	Biotin-amyloid β-peptide (1-42) (human) TFA
	Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the pathogenesis of Alzheimer's disease [1].
T14199	ALZ-801	Valiltramiprosate	Beta Amyloid
	ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly improved candidate for the treatment of Alzheimer's disease. ALZ-801 is a potent and orally available small-m...		Beta Amyloid
TP1230	β-Amyloid (1-42), (rat/mouse)	β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)
	Amyloid (1-42), rat is a polypeptide composed of 42 amino acids. It is toxic to hippocampal slices and can be used in the study of alzheimer's disease.

Compounds

β-Amyloid 15-21 acetate

TP1214L

Synonym: Beta-Amyloid (15-21) acetate

Target: Beta Amyloid

β-Amyloid (1-15)

TP1229

Synonym: Amyloid β-Protein (1-15)

Target: Beta Amyloid

β-Amyloid (31-35)

T7562

Synonym: β-Amyloid 31-35(TFA),β-Amyloid 31-35

Target: Beta Amyloid

β-Amyloid (25-35)

T14284

Synonym: β-Amyloid peptide(25-35),Aβ25-35,Amyloid beta-peptide(25-35)

Target: Beta Amyloid

Amyloid β-Protein 10-20 acetate

TP1786L

Synonym: Amyloid β-Protein 10-20 acetate(152286-31-2 free base)

Target: Beta Amyloid

β-Amyloid (1-42), (rat/mouse) (TFA)

T35499

Synonym: Amyloid β-peptide (1-42) (human) TFA,166090-74-0 TFA

Target:

β-amyloid 1-11 acetate(190436-05-6 free base)

TP1866L

Synonym:

Target: Beta Amyloid

β-Amyloid (1-42), acetate (human)

TP1007L

Synonym: β-Amyloid (1-42), human acetate (107761-42-2 Free base)

Target:

Amyloid β Peptide (42-1)(human) acetate

TP1359L

Synonym: Amyloid β Peptide (42-1)(human) acetate(317366-82-8 free base)

Target: Beta Amyloid

β-Amyloid (1-37) (human)

T37768

Synonym:

Target:

β-Amyloid (1-43)(human)

T38149

Synonym:

Target:

Amyloid-β (1-8) Peptide

T37368

Synonym:

Target:

Biotin-β-Amyloid (1-40)

T39285

Synonym:

Target:

β-Amyloid (1-14),mouse,rat

T35498

Synonym:

Target:

β-Amyloid (1-38), mouse, rat

T39302

Synonym:

Target:

Amyloid-β (1-8, A2V) Peptide

T37369

Synonym: Amyloid-β (1-8, A2V) Peptide

Target:

β-Amyloid (1-28)

TP1226

Synonym: Amyloid β-Protein (1-28),β-Amyloid 1-28

Target:

β-Amyloid (1-40), FAM-labeled

Synonym: β-Amyloid 1-40

Target:

β-Amyloid (13-27)

TP1692

Synonym: β-Amyloid 13-27

Target:

β-Amyloid (1-17)

TP1500

Synonym: β-Amyloid 1-17

Target:

β-Amyloid (4-10)

TP1494

Synonym: β-Amyloid 4-10

Target:

β-Amyloid (1-20)

TP1538

Synonym: β-Amyloid 1-20

Target:

β-Amyloid (29-40)

TP1231

Synonym: Amyloid beta-protein(29-40),β-Amyloid 29-40

Target:

β-Amyloid (1-16)

TP1228

Synonym: Amyloid β-Protein (1-16),β-Amyloid 1-16

Target:

β-Amyloid (22-35)

TP1225

Synonym: β-Amyloid 22-35,Amyloid β-Protein (22-35)

Target:

β-Amyloid (10-20)

TP1786

Synonym: Amyloid β-Protein 10-20

Target:

β-Amyloid (33-40)

TP1719

Synonym: β-Amyloid 33-40

Target:

β-Amyloid (35-42)

TP1586

Synonym: β-Amyloid 35-42

Target:

β-Amyloid (1-11)

TP1866

Synonym: β-amyloid 1-11

Target:

β-Amyloid (22-40)

TP1544

Synonym: β-Amyloid 22-40

Target:

β-Amyloid (1-9)

TP1645

Synonym: β-Amyloid 1-9

Target:

β-Amyloid (12-28)

TP1227

Synonym: β-amyloid 12-28,Amyloid β-Protein (12-28)

Target:

β-Amyloid (11-22)

TP1673

Synonym: β-Amyloid 11-22

Target:

Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Synonym: β-Amyloid 12-20

Target:

β-Amyloid (1-34)

TP1599

Synonym: β-Amyloid 1-34

Target:

β-Amyloid (18-28)

TP1633

Synonym: β-Amyloid 18-28

Target:

TAMRA-Amyloid-β (1-42) Peptide (trifluoroacetate salt)

Target: Gamma-secretase

Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)

Synonym: Beta-Amyloid (15-21)

Target:

β-Amyloid (1-42), human

TP1007

Synonym: β-Amyloid (1-42), human,Amyloid β-Peptide (1-42) human

Target: Beta Amyloid

5-FAM-β-Amyloid (1-28)

T80037

Synonym: 5-FAM-Amyloid β-protein (1-28)

Target:

Biotin-Amyloid-β (1-42) Peptide (trifluoroacetate salt)

T37200

Synonym:

Target:

β-Amyloid (42-1), human

TP1359

Synonym: Amyloid β Peptide (42-1)(human)

Target:

β-Amyloid (1-40) (rat)

TP1441

Synonym: Amyloid β-peptide (1-40) rat

Target:

Biotin-β-Amyloid (1-42), human TFA

T80035

Synonym: Biotin-amyloid β-peptide (1-42) (human) TFA

Target:

ALZ-801

T14199

Synonym: Valiltramiprosate

Target: Beta Amyloid

β-Amyloid (1-42), (rat/mouse)

TP1230

Synonym: β-Amyloid (1-42), rat,Amyloid β-peptide (1-42) (rat)

Target:

Cat No.	Product Name	Synonyms	Targets
TN6919	Methyl tridecanoate		Beta Amyloid , AChE
	Methyl tridecanoate is a natural product.		Beta Amyloid , AChE
T2212	Geniposide		Beta Amyloid , Influenza Virus
	Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation...		Beta Amyloid , Influenza Virus
T3914	Saikosaponin C		Beta Amyloid , Caspase
	Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.		Beta Amyloid , Caspase
T8012	Scyllo-Inositol	Scyllitol	Beta Amyloid , Endogenous Metabolite
	Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent for Alzheimer's disease.		Beta Amyloid , Endogenous Metabolite
T4S0350	Licochalcone B		Beta Amyloid , Others
	1. Licochalcone B (LCB) inhibits the proliferation of human malignant bladder cancer cell lines (T24 and EJ) in vitro and antitumor activity in vivo in MB49 (murine bladder cancer cell line) tumor model. 2. LCB and Licoc...		Beta Amyloid , Others
TMS1461	Qingyangshengenin B	Otophylloside B	Beta Amyloid
	Qingyangshengenin B (Otophylloside B) is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mR...		Beta Amyloid
T0795	Rutin	Quercetin 3-O-rutinoside,Rutoside	Beta Amyloid , Prostaglandin Receptor , Autophagy
	Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.		Beta Amyloid , Prostaglandin Receptor , Autophagy
T6S1918	Schisantherin B	Gomisin-B,Wuweizi ester-B,Schizantherin-B	Beta Amyloid , Others
	1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Beta Amyloid , Others
T22417	Rutin hydrate	Rutoside,Sophorin,Quercetin-3-O-rutinoside	Beta Amyloid , Others , Autophagy
	Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.		Beta Amyloid , Others , Autophagy
T0883	Tramiprosate	Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed	Beta Amyloid , GABA Receptor
	Tramiprosate (Alzhemed) is an orally active, blood-brain-barrier-crossing, naturally occurring amino acid found in a variety of red seaweeds that binds soluble Aβ and maintains it in a non-protofibrillar form.It is a GAB...		Beta Amyloid , GABA Receptor
T1686	Hematoxylin	Hydroxybrazilin,Natural Black 1,Haematoxylin	Beta Amyloid , Others
	Hematoxylin (Natural Black 1) is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used as a stain in microscopy and in the manufacture of ink.		Beta Amyloid , Others
T2872	Ginsenoside Re	Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re	Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.		Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
T2961	Notoginsenoside R1	Sanqi glucoside R1,Sanchinoside R1	Apoptosis , ERK , Beta Amyloid
	Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.		Apoptosis , ERK , Beta Amyloid
T2777	Ginsenoside Rg1	Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2	Apoptosis , Beta Amyloid , NF-κB
	Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level i...		Apoptosis , Beta Amyloid , NF-κB
T2873	Ginsenoside Rg2	Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2	Beta Amyloid , GSK-3 , NF-κB
	Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.		Beta Amyloid , GSK-3 , NF-κB
T3402	20(S)-Ginsenoside Rg3	20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
	20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
TN1653	Fustin		ERK , Beta Amyloid , AChR
	Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.		ERK , Beta Amyloid , AChR
TN4368	Kaempferol-3,7-di-O-β-glucoside	Kaempferol 3,7-di-O-glucoside	Glucosidase , Amylase
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...		Glucosidase , Amylase
T3769	Tenuifolin		Others , Beta-Secretase , AChE
	Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.		Others , Beta-Secretase , AChE
TL0007	Bisdemethoxycurcumin	Curcumin III,Didemethoxycurcumin	Epigenetic Reader Domain , Wnt/beta-catenin
	Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac...		Epigenetic Reader Domain , Wnt/beta-catenin
T32614	L-Clausenamide	(-)-Clausenamide	Microtubule Associated
	L-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents t...		Microtubule Associated
T37957	Setosusin
	Setosusin is a meroterpenoid fungal metabolite originally isolated from C. setosus. It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM). In vivo, setosusin (30 mg/kg) induces tre...
T79968	Coumarinic acid
	Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].
T83407	2',3'-Dihydroxy-4',6'-dimethoxychalcone
	2',3'-Dihydroxy-4',6'-dimethoxychalcone (compound 1) possesses the capacity to inhibit Amyloid β-protein (Aβ42) fibrillization and aggregation, demonstrating oral activity with detectable presence in the brain [1].

Natural Products

Methyl tridecanoate

TN6919

Synonym:

Target: Beta Amyloid, AChE

Geniposide

T2212

Synonym:

Target: Beta Amyloid, Influenza Virus

Saikosaponin C

T3914

Synonym:

Target: Beta Amyloid, Caspase

Scyllo-Inositol

T8012

Synonym: Scyllitol

Target: Beta Amyloid, Endogenous Metabolite

Licochalcone B

T4S0350

Synonym:

Target: Beta Amyloid, Others

Qingyangshengenin B

TMS1461

Synonym: Otophylloside B

Target: Beta Amyloid

Rutin

T0795

Synonym: Quercetin 3-O-rutinoside,Rutoside

Target: Beta Amyloid, Prostaglandin Receptor, Autophagy

Schisantherin B

T6S1918

Synonym: Gomisin-B,Wuweizi ester-B,Schizantherin-B

Target: Beta Amyloid, Others

Rutin hydrate

T22417

Synonym: Rutoside,Sophorin,Quercetin-3-O-rutinoside

Target: Beta Amyloid, Others, Autophagy

Tramiprosate

T0883

Synonym: Homotaurine,3-Amino-1-propanesulfonic acid,Alzhemed

Target: Beta Amyloid, GABA Receptor

Hematoxylin

T1686

Synonym: Hydroxybrazilin,Natural Black 1,Haematoxylin

Target: Beta Amyloid, Others

Ginsenoside Re

T2872

Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

Notoginsenoside R1

T2961

Synonym: Sanqi glucoside R1,Sanchinoside R1

Target: Apoptosis, ERK, Beta Amyloid

Ginsenoside Rg1

T2777

Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2

Target: Apoptosis, Beta Amyloid, NF-κB

Ginsenoside Rg2

T2873

Synonym: Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2

Target: Beta Amyloid, GSK-3, NF-κB

20(S)-Ginsenoside Rg3

T3402

Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Fustin

TN1653

Synonym:

Target: ERK, Beta Amyloid, AChR

Kaempferol-3,7-di-O-β-glucoside

TN4368

Synonym: Kaempferol 3,7-di-O-glucoside

Target: Glucosidase, Amylase

Tenuifolin

T3769

Synonym:

Target: Others, Beta-Secretase, AChE

Bisdemethoxycurcumin

TL0007

Synonym: Curcumin III,Didemethoxycurcumin

Target: Epigenetic Reader Domain, Wnt/beta-catenin

L-Clausenamide

T32614

Synonym: (-)-Clausenamide

Target: Microtubule Associated

2',3'-Dihydroxy-4',6'-dimethoxychalcone

T83407

Synonym:

Target:

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04693	APLP1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amy...
TMPY-03884	Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03885	Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-03628	APLP1 Protein, Human, Recombinant (His)	Human	HEK293
	APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amy...
TMPY-02110	Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPY-02221	Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)	Human	E. coli
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPJ-00684	SNCA Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's ...
TMPJ-00683	SNCA Protein, Mouse, Recombinant	Mouse	E. coli
	Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and hist...
TMPJ-00023	SNCA Protein, Human, Recombinant (His)	Human	E. coli
	Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and hist...
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc)	Human	HEK293
	Amyloid precursor protein (APP) is a type I transmembrane protein expressed in many tissues and concentrated in the synapses of neurons, and is suggested as a regulator of synapse formation and neural plasticity. APP can...
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
TMPJ-00722	APBA3 Protein, Human, Recombinant (His)	Human	E. coli
	Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloi...
TMPJ-00851	IDE Protein, Human, Recombinant (His)	Human	Human Cells
	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a r...
TMPK-00935	APLP2 Protein, Human, Recombinant (His)	Human	HEK293
	Amyloid β precursor-like protein 2 (APLP2) has been determined to serve an important role in the progression of a number of cancer types. APLP2 expression was significantly associated with disease-specific survival (P<0....
TMPK-00998	SEZ6 Protein, Human, Recombinant (His)	Human	HEK293
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00997	SEZ6 Protein, Human, Recombinant (hFc)	Human	HEK293
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00996	SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-01065	SEZ6 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-00541	SEZ6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform o...
TMPK-01146	LGMN Protein, Human, Recombinant (His)	Human	HEK293
	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in th...
TMPY-03065	BACE2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	BACE2, also known as beta secretase 2, belongs to the peptidase A1 family. It is a protease known to be an important enzyme involved in the cellular pathways. BACE2 has been shown to interact with GGA1 and GGA2. It is th...
TMPJ-01235	B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	Human Cells
	β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecule...
TMPJ-01236	B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)	Cynomolgus	Human Cells
	β-2-Microglobulin (B2M) is a secreted protein with 1 Ig-like C1-type (immunoglobulin-like) domain which belongs to the beta-2-microglobulin family. B2M component of major histocompatibility complex (MHC) class I molecule...
TMPJ-00292	CD36 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ...

APLP1 Protein, Mouse, Recombinant (His)

TMPY-04693

Species: Mouse

Expression System: HEK293

Beta-amyloid 39/Beta-APP39 Protein, Human, Recombinant (aa 672-710, His & GST)

TMPY-03884

Species: Human

Expression System: E. coli

Beta-amyloid 38/Beta-APP38 Protein, Human, Recombinant (aa 672-709, His & GST)

TMPY-03885

Species: Human

Expression System: E. coli

APLP1 Protein, Human, Recombinant (His)

TMPY-03628

Species: Human

Expression System: HEK293

Beta-amyloid 40/Beta-APP40 Protein, Human, Recombinant (His & GST)

TMPY-02110

Species: Human

Expression System: E. coli

Beta-amyloid 42/Beta-APP42 Protein, Human, Recombinant (His & GST)

TMPY-02221

Species: Human

Expression System: E. coli

SNCA Protein, Mouse, Recombinant (His)

TMPJ-00684

Species: Mouse

Expression System: E. coli

SNCA Protein, Mouse, Recombinant

TMPJ-00683

Species: Mouse

Expression System: E. coli

SNCA Protein, Human, Recombinant (His)

TMPJ-00023

Species: Human

Expression System: E. coli

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

TMPY-00668

Species: Human

Expression System: HEK293

LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00338

Species: Human

Expression System: Human Cells

APBA3 Protein, Human, Recombinant (His)

TMPJ-00722

Species: Human

Expression System: E. coli

IDE Protein, Human, Recombinant (His)

TMPJ-00851

Species: Human

Expression System: Human Cells

APLP2 Protein, Human, Recombinant (His)

TMPK-00935

Species: Human

Expression System: HEK293

SEZ6 Protein, Human, Recombinant (His)

TMPK-00998

Species: Human

Expression System: HEK293

SEZ6 Protein, Human, Recombinant (hFc)

TMPK-00997

Species: Human

Expression System: HEK293

SEZ6 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00996

Species: Human

Expression System: HEK293

SEZ6 Protein, Mouse, Recombinant (His)

TMPK-01065

Species: Mouse

Expression System: HEK293

SEZ6 Protein, Cynomolgus, Recombinant (His)

TMPK-00541

Species: Cynomolgus

Expression System: HEK293

LGMN Protein, Human, Recombinant (His)

TMPK-01146

Species: Human

Expression System: HEK293

BACE2 Protein, Mouse, Recombinant (His)

TMPY-03065

Species: Mouse

Expression System: HEK293

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (hFc)

TMPJ-01235

Species: Cynomolgus

Expression System: Human Cells

B2M/beta 2-Microglobulin Protein, Cynomolgus, Recombinant (aa 21-119, His)

TMPJ-01236

Species: Cynomolgus

Expression System: Human Cells

CD36 Protein, Human, Recombinant (hFc)

TMPJ-00292

Species: Human

Expression System: Human Cells

Cat No.	Product Name
L9840	Anti-Alzheimer's Disease Compound Library		1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

Libraries

Anti-Alzheimer's Disease Compound Library

L9840

Compounds: 1040