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Search Result

Search Results for "aryl hydrocarbon receptor"

Targets

Aryl Hydrocarbon Receptor

Compounds

Cat No. Product Name
T7202 ITE AhR , Aryl Hydrocarbon Receptor
ITE 是一种有效的芳烃受体 (AhR) 内源性激动剂，Ki 值为 3 nM。它具有免疫抑制作用。
TQ0257 FICZ 6-Formylindolo[3,2-b]carbazole Aryl Hydrocarbon Receptor
FICZ 是芳烃受体 (AhR) 的有效芳基激动剂，Kd 值为70 pM。
T15410 GNF351 Aryl Hydrocarbon Receptor
GNF351 是芳烃受体 (AhR) 的完全拮抗剂，具有抑制 DRE 依赖性和非依赖性活性的能力。它与结合到 AhR 的光亲和性 AhR 配体竞争，IC50为 62 nM。它在小鼠或人角质形成细胞中的毒性极小。
T1831 StemRegenin 1 SR1 AhR , Aryl Hydrocarbon Receptor
StemRegenin 1 是一种芳香烃受体拮抗剂，IC50为 127 nM。
T10270 BAY 2416964 Aryl Hydrocarbon Receptor
BAY 2416964 是一种可口服的芳基烃受体拮抗剂，IC50为 341 nM，可用于研究实体瘤。详细信息请参考专利文献 WO2018146010A1 中的化合物 192。
T2448 CH-223191 CH 223191 AhR , Aryl Hydrocarbon Receptor
CH-223191 是一种特异性有效的芳烃受体 (AhR) 拮抗剂，可抑制 TCDD 介导的核转位和 AhR 的 DNA 结合，抑制 TCDD 诱导的荧光素酶活性的 IC50值为 0.03 μM。
T21966 MeBIO Aryl Hydrocarbon Receptor , CDK , GSK-3
MeBIO 是一种芳烃受体激动剂，对 GSK-3 和 CDK1/CyclinB 的 IC50 分别为 44 和 55 μM。 MeBIO 不影响 GSK-3β。
T4608 PDM2 AhR , Aryl Hydrocarbon Receptor
PDM2 是一种有效的选择性芳烃受体 (AhR) 拮抗剂，Ki 为 1.2±0.4 nM。
TN1451 Brevifolincarboxylic acid AhR , Glucosidase , Aryl Hydrocarbon Receptor
Brevifolincarboxylic acid 是从头状蓼中分离得到的一种天然产物，抑制芳烃受体(AhR)。它是一种 α-葡萄糖苷酶抑制剂，IC50 为 323.46 μM。
T5622 BAY-218 AHR antagonist 1 AhR , Aryl Hydrocarbon Receptor
AHR antagonist 1 是一种芳基烃受体(AHR)拮抗剂，在人细胞系中的IC50值为 39.9 nM，详细信息请参考WO2017202816A1中的Example 23。
T10007 1,4-Chrysenequinone 1,4-屈醌,Chrysene-1,4-dione AhR
1,4-Chrysenequinone 是多环芳香烃类，是芳烃受体 (AhR) 的激活剂
T20625 Prochloraz 咪鲜胺,Sporgon,Prelude Androgen Receptor , AhR , Antifungal , Estrogen Receptor/ERR
Prochloraz 是咪唑类抗真菌剂。Prochloraz 抑制羊毛甾醇的细胞色素 P450 依赖性 14α-脱甲基作用，由此抑制麦角固醇的生物合成，从而导致真菌细胞膜破裂和细胞死亡。它也是雌激素受体和 雄激素受体的拮抗剂，IC50分别为...
T21704 5-fluoro 203 5F-203,NSC-703786 Others
5-fluoro 203 是一种细胞毒性分子。它可激活芳香烃受体(AhR) 信号传导，诱导 CYP1A1 的转录，从而形成 DNA 加合物以及细胞周期阻滞。它可以提高活性氧水平，并激活 ERK、p38以及JNK。
T13276 VAF347 4-(3-氯苯基)-N-[4-(三氟甲基)苯基]嘧啶-2-胺 Aryl Hydrocarbon Receptor
VAF347 是细胞可渗透且高度亲和力的芳烃受体激动剂，可诱导AhR 信号传导，具有抗炎作用。它抑制颗粒单核细胞 (GM 期) 前体中 CD14+CD11b+单核细胞的发育。
T1960 YL-109 Aryl Hydrocarbon Receptor , AhR
YL-109是一种抗肿瘤剂，可以通过芳烃受体 AhR 信号传导诱导 Hsp70 相互作用蛋白 (CHIP) 表达，具有抑制乳腺癌细胞生长和侵袭性的能力。
T4607 CAY 10465 CAY10465 Exclusive,CAY10465 Aryl Hydrocarbon Receptor , AhR
CAY10465 是一种选择性和高亲和力的芳香烃受体(AhR)激动剂，Ki 值为 0.2 nM。
T6795 Carbidopa (S)-(-)-Carbidopa,Lodosyn,卡比多巴 Aryl Hydrocarbon Receptor , Decarboxylase
Carbidopa 是一种选择性芳香烃受体(AhR)调节剂，是外周型脱羧酶抑制剂，抑制胰腺癌细胞和肿瘤生长，可用于帕金森病的研究。
T8980 SGA360 Aryl Hydrocarbon Receptor
SGA360 是选择性芳烃 (Ah) 受体调节剂。 它具有抗炎特性。
T5541 PDM11 PDM 11,1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth AhR
PDM11 是抗氧化剂白藜芦醇的衍生物。它在白藜芦醇活性测定中不活跃。它对辐射分解产生的羟基自由基引发的亚油酸胶束氧化没有明显的保护作用。
T10269 AHR antagonist 2 Aryl Hydrocarbon Receptor
AHR antagonist 2 是芳基烃受体的拮抗剂。 人 AHR 和小鼠 AHR 的 IC50 分别为 0.885 和 2.03 nM。
ITE
T7202
synonym:
Target:
FICZ
TQ0257
synonym: 6-Formylindolo[3,2-b]carbazole
Target:
GNF351
T15410
synonym:
Target:
StemRegenin 1
T1831
synonym: SR1
Target:
BAY 2416964
T10270
synonym:
Target:
CH-223191
T2448
synonym: CH 223191
Target:
MeBIO
T21966
synonym:
Target:
PDM2
T4608
synonym:
Target:
Brevifolincarboxylic acid
TN1451
synonym:
Target:
BAY-218
T5622
synonym: AHR antagonist 1
Target:
1,4-Chrysenequinone
T10007
synonym: 1,4-屈醌,Chrysene-1,4-dione
Target:
Prochloraz
T20625
synonym: 咪鲜胺,Sporgon,Prelude
Target:
5-fluoro 203
T21704
synonym: 5F-203,NSC-703786
Target:
VAF347
T13276
synonym: 4-(3-氯苯基)-N-[4-(三氟甲基)苯基]嘧啶-2-胺
Target:
YL-109
T1960
synonym:
Target:
CAY 10465
T4607
synonym: CAY10465 Exclusive,CAY10465
Target:
Carbidopa
T6795
synonym: (S)-(-)-Carbidopa,Lodosyn,卡比多巴
Target:
SGA360
T8980
synonym:
Target:
PDM11
T5541
synonym: PDM 11,1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth
Target:
AHR antagonist 2
T10269
synonym:
Target:
1 2 3
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