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Search Results for " biofilm "

Targets

72

Compounds

29

Natural Products

10

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8507 MAC-545496 Antibacterial
MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.
T1305 Ceftazidime GR20263 Antibacterial , Antibiotic
Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity.
T18408 N-Butanoyl-L-homoserine lactone N-Butyryl-L-homoserine lactone,C4-HSL Antibacterial
N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm...
T83096 Antibiofilm agent-2
Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron homeostasis, acting as antibacterial synergists against Pseudomo...
T12094 Monobehenin Others , Antibacterial
Monobehenin has a strong inhibitory effect on the formation of bacterial biofilm.
T13947 Tween 80 Others
Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the ...
T35805 C16 Sphingomyelin (d18:1/16:0) Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin Endogenous Metabolite
C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.
T78823 Quorum Sensing-IN-3 QS-IN-1 Antibacterial
Quorum Sensing-IN-3 (QS-IN-1) is a compound with inhibitory effects on bacterial community sensing, which inhibits the exchange of information between bacteria and inhibits biofilm formation.
T13789 N-dodecanoyl-L-Homoserine lactone C12-HSL Others
N-dodecanoyl-L-Homoserine lactone (C12-HSL) is a quorum sensing (QS) signaling molecule, a microbial communication mechanism modulated by acyl homoserine lactone (AHL) molecules impacts biofilm formation in bioreactors.
T78226 Methyl 2-amino-5-bromobenzoate Methyl 5-Bromoanthranilate HCV Protease , Antifungal
Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is a hepatitis C virus NS5b RNA polymerase inhibitor with antimicrobial activity that inhibits Pseudomonas aeruginosa infections and is involved in the producti...
T77521 HA5 Antibacterial
HA5 has antimicrobial activity and inhibits the biofilm formation of Streptococcus mutans with an IC50 value of 6.42 μM. HA5 inhibits the production of Streptococcus mutans dextran and the level of eDNA, but it does not ...
T124492 Imipenem N-Formimidoyl thienamycin,MK0787 Antifungal
Imipenem (MK0787) is a thienomycin derivative that belongs to the class of antibiotics with antibacterial activity and partial inhibition against gram-positive and gram-negative bacteria. Imipenem can be used to study ca...
T36983 Cyclic-di-GMP disodium Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium STING , Endogenous Metabolite
Cyclic-di-GMP disodium (5GP-5GP disodium) is a bacterial second messenger and a STING agonist involved in a variety of prokaryotic processes including biofilm formation, motility, and cell cycle progression.Cyclic-di-GMP...
T63894 Octenidine
Octenidine is an effective antibacterial agent that inhibits biofilm gene expression, disrupts biofilm formation and is able to inhibit multi-resistant Gram-negative pathogens.
T13788 N-Butanoyl-DL-homoserine lactone (Rac)-C4-HSL Others
N-Butanoyl-DL-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa.
T71508 TCSA
TCSA is an inhibitor of fungal morphogenesis, biofilm formation, and host cell invasion.
T70386 QZN34
QZN34 is a PqsR inhibitor which prevents S. aureus biofilm formation, severely damaged established S. aureus biofilms, and perturbed P. aeruginosa biofilm development. The mechanism of action of QZN 34 toward Gram-positi...
T80123 CRAMP (mouse)
CRAMP (mouse), an antimicrobial peptide, is utilized in the study of biofilm-associated infections [1].
T61126 Antibacterial synergist 1
Antibacterial synergist 1 (compound 20P) is a potent inhibitor of bacterial biofilm formation. It effectively suppresses the production of pyocyanin, with an IC 50 of 8.6 μM, and inhibits biofilm formation with an IC 50 ...
T30767 CB-181963 CB 181963,CB181963,UNII-6784994L0W,CAB 175
CB-181963, a new cephalosporin, is an effective antistaphylococcal drug, showing excellent activity against the resistance of MRSA strains to other cephalosporins in planktonic and biofilm cultures.
T37555 Cardanol triene
Cardanol triene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 40.5 μM in vitro. A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal c...
T68343 PyrD-IN-14
PyrD-IN-14 is an inhibitor of the PyrD protein (a dihydroorotate dehydrogenase (DHODase) involved in pyrimidine biosynthesis) which suppresses bacterial cytotoxicity, biofilm formation, and antibiotic resistance.
T74272 Antifungal agent 84
Antibacterial Agent 84, an antifungal compound, effectively inhibits candidiasis through a CNB1-dependent mechanism and reduces the viability of the C. albicans biofilm [1].
T74820 Antibacterial agent 142
Antibacterial agent 142, an aromatic hydrazide, exhibits bacteriostatic antibacterial activity and inhibits biofilm formation [1].
T79468 Antimicrobial agent-22
Antimicrobial agent-22 (THI 6c) constitutes a broad-spectrum, multi-target antibacterial with notable rapid bactericidal efficacy and effective anti-biofilm activity, paired with low cytotoxicity and hemolytic properties...
T37464 CAY10711
CAY10711 is a substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant S. aureus (MRSA) and stationary-phase bacteria. It displa...
T79555 G43-C3-TEG
G43-C3-TEG is a glycosyl-transferase inhibitor that diminishes biofilm formation by inhibiting the synthesis of extracellular polysaccharides (EPS) [1].
T61366 F-17
F-17 is a promising virulence factor inhibitor, displaying substantial inhibitory effects on biofilm formation, elastase activity, pyocyanin production, and swarming motility. Additionally, F-17 exhibits a strong binding...
T71813 Cardanol diene
Cardanol diene is a phenol found in cashew nut shell liquid that inhibits tyrosinase with an IC50 value of 52.5 μM in vitro. Cardanol diene is also used to synthesize cardanol-metal complexes that inhibit uropathogenic E...
T64029 Antifungal agent 42
Antifungal agent 42 is an antifungal agent that has an inhibitory effect on biofilm formation. Antifungal agent 42 inhibits C.alb.'s lanosterol 14α-demethylase (CYP51).
T63500 Alexidine
Alexidine is an antifungal and anti-biofilm agent against a variety of fungal pathogens. alexidine targets the mitochondrial tyrosine phosphatase PTPMT1 in mammalian cells, causing mitochondrial apoptosis and exhibiting ...
T75176 Antifungal agent 53
Antifungal Agent 53 (A03), a potent Candida albicans CYP51 inhibitor, exhibits antifungal activity by preventing fungi biofilm formation and demonstrates good safety [1].
T72333 Antibacterial agent 64
Antibacterial agent 64, a potent YycG inhibitor (IC50=6.1 µM), serves as an effective antibacterial agent. When combined with ampicillin, it synergistically eradicates biofilm-embedded viable bacteria.
T60610 LasR-IN-4
LasR-IN-4 is a potent inhibitor of LasR which inhibits Pseudomonas aeruginosa and its biofilm formation, pyocyanin production, and rhamnolipids production [1].
T63711 Antifungal agent 43
Antifungal agent 43 is an antifungal agent that exhibits antifungal effect by inhibiting biofilm formation. antifungal agent 43 shows low toxicity to human cancer cell lines.
T61502 Antifungal agent 32
Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological sw...
T79561 Mtb-IN-5
Mtb-IN-5 (compound (-)17j) is an isoxazole exhibiting anti-Mycobacterium tuberculosis (Mtb) activity. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isonia...
T37263 14-methyl Pentadecanoic Acid methyl ester
14-methyl Pentadecanoic acid methyl ester is a methylated fatty acid methyl ester that has been found in S. zeai sea sponges as the fatty acyl component of zeamide, A. indica leaf extract, and C. vulgaris and H. pluviali...
T61108 YXL-13
YXL-13 is a highly effective inhibitor of Pseudomonas aeruginosa (PAO1), with an IC50 value of 3.686 μM. It effectively hinders the expression of virulence factors and inhibits biofilm formation in PAO1. Moreover, YXL-13...
T63285 Antifungal agent 40
Antifungal agent 40 is an antifungal agent that extends into the narrow hydrophobic pocket II of C. alb. CYP51 and inhibits the activity of lanosterol 14α-demethylase (CYP51), which has an inhibitory effect on biofilm fo...
T60291 β-Nor-lapachone
β-Nor-lapachone is an antibiofilm agent of Candida glabrata. β-Nor-lapachone can stimulate ROS production, inhibits efflux activity, adhesion, biofilm formation and the metabolism of mature biofilms of Candida glabrata. ...
T37335 N-3-hydroxybutyryl-L-Homoserine lactone
N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic v...
T83069 Antifungal agent 75
Antifungal agent 75 (compound 6r) effectively combats Candida albicans by substantially inhibiting biofilm formation, enhancing cell membrane permeability, diminishing membrane ergosterol levels, impairing membrane struc...
T74029 Cis-11-Methyl-2-dodecenoic acid
Cis-11-Methyl-2-dodecenoic acid functions as a quorum sensing (QS) signal and a diffusion signaling factor (DSF) within extracellular microbial and fungal communication systems. It plays a pivotal role in regulating viru...
T72304 Antibacterial agent 126
Antibacterial Agent 126 is a potent agent that not only reduces biofilm burden to prevent drug resistance development but also disrupts membrane integrity, resulting in the leakage of intracellular contents. Additionally...
T76585 Hepcidin-20 (human)
Hepcidin-20 (human), a peptide characterized by its histidine content, cysteine-rich composition, and β-sheet structure, exhibits antifungal properties. Furthermore, it effectively inhibits biofilm formation and disrupts...
T60965 Anticandidal agent-1
Anticandidal agent-1 (compound c2) is a potent and broad-spectrum anticandidal agent that inhibits biofilm through blocking hyphal elongation and filamentation. Anticandidal agent-1 exhibits anticandidal activity against...
T74269 Antibacterial agent 83
Antibacterial agent 83 (compound 17h) exhibits strong antibacterial efficacy against diverse strains of vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA), significant...
T60249 RhlR antagonist 1
RhlR antagonist 1 is a highly effective antagonist of the RhlR protein, showing an IC50 value of 26 μM. It exhibits selective antagonistic activity against RhlR, with minimal effect on LasR and PqsR. RhlR antagonist 1 st...
T79559 Mtb-IN-4
Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity, with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augmen...

Compounds

MAC-545496
T8507
Synonym:
Target: Antibacterial
Ceftazidime
T1305
Synonym: GR20263
Target: Antibacterial, Antibiotic
N-Butanoyl-L-homoserine lactone
T18408
Synonym: N-Butyryl-L-homoserine lactone,C4-HSL
Target: Antibacterial
Antibiofilm agent-2
T83096
Synonym:
Target:
Monobehenin
T12094
Synonym:
Target: Others, Antibacterial
Tween 80
T13947
Synonym:
Target: Others
C16 Sphingomyelin (d18:1/16:0)
T35805
Synonym: Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin
Target: Endogenous Metabolite
Quorum Sensing-IN-3
T78823
Synonym: QS-IN-1
Target: Antibacterial
N-dodecanoyl-L-Homoserine lactone
T13789
Synonym: C12-HSL
Target: Others
Methyl 2-amino-5-bromobenzoate
T78226
Synonym: Methyl 5-Bromoanthranilate
Target: HCV Protease, Antifungal
HA5
T77521
Synonym:
Target: Antibacterial
Imipenem
T124492
Synonym: N-Formimidoyl thienamycin,MK0787
Target: Antifungal
Cyclic-di-GMP disodium
T36983
Synonym: Cyclic diguanylate,5GP-5GP disodium,3',5'-Cyclic diguanylic acid,Cyclic di-GMP (sodium salt),cyclic diguanylate disodium,c-di-GMP,c-di-GMP disodium
Target: STING, Endogenous Metabolite
Octenidine
T63894
Synonym:
Target:
N-Butanoyl-DL-homoserine lactone
T13788
Synonym: (Rac)-C4-HSL
Target: Others
TCSA
T71508
Synonym:
Target:
QZN34
T70386
Synonym:
Target:
CRAMP (mouse)
T80123
Synonym:
Target:
Antibacterial synergist 1
T61126
Synonym:
Target:
CB-181963
T30767
Synonym: CB 181963,CB181963,UNII-6784994L0W,CAB 175
Target:
Cardanol triene
T37555
Synonym:
Target:
PyrD-IN-14
T68343
Synonym:
Target:
Antifungal agent 84
T74272
Synonym:
Target:
Antibacterial agent 142
T74820
Synonym:
Target:
Antimicrobial agent-22
T79468
Synonym:
Target:
CAY10711
T37464
Synonym:
Target:
G43-C3-TEG
T79555
Synonym:
Target:
F-17
T61366
Synonym:
Target:
Cardanol diene
T71813
Synonym:
Target:
Antifungal agent 42
T64029
Synonym:
Target:
Alexidine
T63500
Synonym:
Target:
Antifungal agent 53
T75176
Synonym:
Target:
Antibacterial agent 64
T72333
Synonym:
Target:
LasR-IN-4
T60610
Synonym:
Target:
Antifungal agent 43
T63711
Synonym:
Target:
Antifungal agent 32
T61502
Synonym:
Target:
Mtb-IN-5
T79561
Synonym:
Target:
14-methyl Pentadecanoic Acid methyl ester
T37263
Synonym:
Target:
YXL-13
T61108
Synonym:
Target:
Antifungal agent 40
T63285
Synonym:
Target:
β-Nor-lapachone
T60291
Synonym:
Target:
N-3-hydroxybutyryl-L-Homoserine lactone
T37335
Synonym:
Target:
Antifungal agent 75
T83069
Synonym:
Target:
cis-11-Methyl-2-dodecenoic acid
T74029
Synonym:
Target:
Antibacterial agent 126
T72304
Synonym:
Target:
Hepcidin-20 (human)
T76585
Synonym:
Target:
Anticandidal agent-1
T60965
Synonym:
Target:
Antibacterial agent 83
T74269
Synonym:
Target:
RhlR antagonist 1
T60249
Synonym:
Target:
Mtb-IN-4
T79559
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
TN1545 D-Tyrosine Tyrosinase
D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm...
T36735 3,5-Di-tert-butylphenol Reactive Oxygen Species , Antifungal
3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.
T3S2340 Usaramine (15E)-Retrorsine,Mucronatine,NISTC15503874 Others , Antibacterial
Usaramine (Mucronatine) demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
T3S1319 (+)-Magnoflorine Escholin,Magnoflorine,Thalictrin,Escholine Others , Antifungal
(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...
T3S1320 (+)-Magnoflorine iodide Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide Others , Antifungal
(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.
T4S1321 (+)-Magnoflorine chloride Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride Others , Antifungal
(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.
TQ0251 (Z)-2-decenoic acid (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid Others
(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ...
T8261 Ceftazidime Pentahydrate Antibacterial , Antibiotic
Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria.
T15254 Ethyl acetoacetate Ethyl acetylacetate Others , Antibacterial
Ethyl acetoacetate (Ethyl acetylacetate) is a bacterial biofilm inhibitor.Ethyl acetoacetate is an ester, an intermediate that can be used in the synthesis of many compounds.
T5S0636 Citric acid Citro,Citretten Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T67731 Holomycin N-Demethylthiolutin DNA/RNA Synthesis
Holomycin (N-Demethylthiolutin) is a secondary metabolite of dithiopyrrolidone. HolomycinHolomycin, an antibiotic secondary metabolite, is required for the biofilm formation of natural photogenic Bacillus galatheae S2753...
T6S2116 Ginkgolic acid C17:1 Phosphatase , PTEN
1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.
TN1925 Methyl anthranilate Others , Antibacterial
Methyl anthranilate is a natural product. Methyl anthranilate is a novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria
T37753 Aureusimine B Cysteine Protease , Antibacterial
Aureusimine B, also known as phevalin, is a natural pyrazinone produced by certain fungi and by Staphylococcus spp., including S. aureus. Its synthesis appears to be initiated by a conserved nonribosomal peptide syntheta...
T6S2384 Poliumoside Reductase
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w...
T38373 2-heptyl-3-hydroxy-4(1H)-Quinolone 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal Others
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB ...
T4723 D-Tagatose D-(-)-Tagatose,d-tagatos Others , Endogenous Metabolite
D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods such as sterilized and...
T10933 D-Cysteine Endogenous Metabolite , Antibacterial
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cystein...
T72235 Antibacterial synergist 2
Antibacterial synergist 2, functioning as a biofilm inhibitor, demonstrates inhibitory effects against pathogens such as S. enterica, S. aureus, P. aeruginosa, and C. albicans. This compound is applicable in research con...
TN5466 Boeravinone B
Boeravinone B, a novel efflux pump inhibitor, apart from inhibiting the MdeA mediated efflux, also significantly inhibit the biofilm formation of S. aureus, boeravinone B may be used in combination with mupirocin for fur...
T80018 Cis-2-Dodecenoic acid
Cis-2-dodecenoic acid, identified in Burkholderia cenocepacia, disrupts bacterial quorum sensing, thereby inhibiting biofilm formation and the production of virulence factors [1].
T72243 Cyclic-di-GMP diammonium 5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium
Cyclic di-GMP (c-di-GMP) diammonium is a STING activator and a global bacterial second messenger, which regulates biofilm formation, motility, and virulence in diverse bacterial species .
T38241 2-Aminoimidazole
2-Aminoimidazole is a potent antibiofilm agent and adjuvant to antimicrobial treatments, which effectively disrupts bacterial self-protection mechanisms by inhibiting biofilm formation and genetically-encoded antibiotic ...
T64248 Cyclic-di-GMP sodium
Cyclic di-GMP sodium (c-di-GMP sodium) is a STING activator and a ubiquitous second messenger that regulates biofilm formation, motility and virulence of various bacteria.
TN1919 (+)-Medioresinol Medioresinol Beta Amyloid , ROS , Antifection
Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α²-secretase, it is a potentially valuable anti...
T35754 Aszonapyrone A
Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, ...
T75967 Bactenecin TFA
Bactenecin TFA (Bactenecin, bovine TFA), a potent 12-aa looped antimicrobial peptide derived from bovine neutrophils, effectively inhibits bacterial and yeast growth and eradicates Trichophyton rubrum fungus. It enhances...
T73602 Phosphorylcholine Phosphocholine Endogenous Metabolite
Phosphorylcholine is widely present in the biological world, which is a phospholipid present in the eukaryotic biofilm, and also in the symbiotic bacteria or pathogens associated with eukaryotes. Phosphorylcholine has im...
T80001 Majoranaquinone Antibiotic
Majoranaquinone demonstrates potent antibacterial activity against four Staphylococcus strains, one Moraxella strain, and one Enterococcus strain. It also acts as an effective efflux pump inhibitor in Escherichia coli AT...

Natural Products

D-Tyrosine
TN1545
Synonym:
Target: Tyrosinase
3,5-Di-tert-butylphenol
T36735
Synonym:
Target: Reactive Oxygen Species, Antifungal
Usaramine
T3S2340
Synonym: (15E)-Retrorsine,Mucronatine,NISTC15503874
Target: Others, Antibacterial
(+)-Magnoflorine
T3S1319
Synonym: Escholin,Magnoflorine,Thalictrin,Escholine
Target: Others, Antifungal
(+)-Magnoflorine iodide
T3S1320
Synonym: Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide
Target: Others, Antifungal
(+)-Magnoflorine chloride
T4S1321
Synonym: Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride
Target: Others, Antifungal
(Z)-2-decenoic acid
TQ0251
Synonym: (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid
Target: Others
Ceftazidime Pentahydrate
T8261
Synonym:
Target: Antibacterial, Antibiotic
Ethyl acetoacetate
T15254
Synonym: Ethyl acetylacetate
Target: Others, Antibacterial
Citric acid
T5S0636
Synonym: Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
Holomycin
T67731
Synonym: N-Demethylthiolutin
Target: DNA/RNA Synthesis
Ginkgolic acid C17:1
T6S2116
Synonym:
Target: Phosphatase, PTEN
Methyl anthranilate
TN1925
Synonym:
Target: Others, Antibacterial
Aureusimine B
T37753
Synonym:
Target: Cysteine Protease, Antibacterial
Poliumoside
T6S2384
Synonym:
Target: Reductase
2-heptyl-3-hydroxy-4(1H)-Quinolone
T38373
Synonym: 2-heptyl-3-hydroxy-4(1H)-Quinolone,PQS,Pseudomonas Quinolone Signal
Target: Others
D-Tagatose
T4723
Synonym: D-(-)-Tagatose,d-tagatos
Target: Others, Endogenous Metabolite
D-Cysteine
T10933
Synonym:
Target: Endogenous Metabolite, Antibacterial
Antibacterial synergist 2
T72235
Synonym:
Target:
Boeravinone B
TN5466
Synonym:
Target:
cis-2-Dodecenoic acid
T80018
Synonym:
Target:
Cyclic-di-GMP diammonium
T72243
Synonym: 5GP-5GP diammonium,c-di-GMP diammonium ; cyclic diguanylate diammonium ; 5GP-5GP diammonium,c-di-GMP diammonium,cyclic diguanylate diammonium
Target:
2-Aminoimidazole
T38241
Synonym:
Target:
Cyclic-di-GMP sodium
T64248
Synonym:
Target:
(+)-Medioresinol
TN1919
Synonym: Medioresinol
Target: Beta Amyloid, ROS, Antifection
Aszonapyrone A
T35754
Synonym:
Target:
Bactenecin TFA
T75967
Synonym:
Target:
Phosphorylcholine
T73602
Synonym: Phosphocholine
Target: Endogenous Metabolite
Majoranaquinone
T80001
Synonym:
Target: Antibiotic

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-03587 GspB Protein, S. gordonii, Recombinant (GST) Streptococcus gordonii E. coli
Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-a...
TMPH-00712 PGAB Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. N-deacetylation promotes PGA export through the PgaA porin.
TMPH-00589 SpoT Protein, E. coli, Recombinant (His & Myc) E. coli E. coli
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme cataly...
TMPH-03569 IcaB Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial ce...
TMPH-00337 HWP1 Protein, Candida albicans, Recombinant (His) Candida albicans E. coli
Major hyphal cell wall protein which plays a role of adhesin and is required for mating, normal hyphal development, cell-to-cell adhesive functions necessary for biofilm integrity, attachment to host, and virulence. Prom...
TMPH-03157 Fimbrillin Protein, Porphyromonas gingivalis, Recombinant (His & Myc) Porphyromonas gingivalis E. coli
Structural subunit of the major fimbriae. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbio...
TMPH-00331 ALS3 Protein, Candida albicans, Recombinant (B2M & His & Myc) Candida albicans E. coli
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans...
TMPH-03571 WalK Protein, S. aureus, Recombinant (His & Myc) Staphylococcus aureus E. coli
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or...
TMPH-00338 PRA1 Protein, Candida albicans, Recombinant (His) Candida albicans Yeast
Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion an...
TMPH-00617 MazF Protein, E. coli, Recombinant (His) E. coli Yeast
Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific endoribonuclease it inhibits protein synthesis by cleaving mRNA and inducing bacterial stasis. It is stable, single-strand specific with mRNA ...
TargetMol