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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0146 | Ac-DEVD-CHO | Apoptosis , Caspase | |
Ac-DEVD-CHO is a specific Caspase-3 inhibitor (Ki: 230 pM).Ac-DEVD-CHO has an inhibitory effect in SLNT-induced apoptosis. | |||
TQ0146L | Ac-DEVD-CHO acetate | Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base) | Caspase |
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3. | |||
T41069 | CHO-C-PEG2-C-CHO | CHO-C-PEG2-C-CHO | |
CHO-C-PEG2-C-CHO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system ... | |||
T21617 | MG-115 | Z-LL-Nva-CHO | Proteasome |
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteas... | |||
T78640 | Z-LLF-CHO | Z-Leu-Leu-Phe-CHO | Proteasome |
Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM. Additionally, this compound serves as an inhibitor of NF-κB ... | |||
T80531 | Ac-AAVALLPAVLLALLAP-DEVD-CHO | DEVD-CHO-CPP 32 | Caspase |
Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1]. | |||
T39722 | CHO-CH2-PEG1-CH2-Boc | CHO-CH2-PEG1-CH2-Boc | |
CHO-CH2-PEG1-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome sys... | |||
T80624 | Ac-VAD-CHO | Ac-Val-Ala-Asp-CHO | Caspase |
Ac-Val-Ala-Asp-CHO (Ac-VAD-CHO) serves as a pan-caspase inhibitor and preserves mitochondrial membrane potential (MMP) while preventing the release of cytochrome c in cells subjected to hypoxia [1]. | |||
T83205 | Ac-DNLD-CHO | Ac-Asp-Asn-Leu-Asp-CHO | Caspase |
Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7 nM, respectively. This compound is utilized in the study of... | |||
T80735 | Z-Gly-Pro-Phe-Leu-CHO | Z-GPFL-CHO | Proteasome |
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde serving as a selective and potent proteasome inhibitor, demonstrating inhibition constants (Ki) of 1.5 µM, 2.3 µM, and 40.5 µM for branched-chain amino acid-p... | |||
T78586L | Ac-IETD-CHO TFA | Ac-IETD-CHO TFA(191338-86-0 Free base ) | Apoptosis , Caspase |
Ac-IETD-CHO TFA is a granzyme B and caspase-8 inhibitor that inhibits caspase8 activity by blocking caspase3 precursor cleavage.Ac-IETD-CHO TFA inhibits Fas-mediated apoptosis. | |||
T41236 | Z-FY-CHO | ||
Z-FY-CHO (Z-Phe-Tyr-CHO) is a specific and potent cathepsin L (CTSL) inhibitor [1] [2]. | |||
T2154 | MG-132 | Z-LLL-al,Z-Leu-Leu-Leu-CHO | Apoptosis , Proteasome , Autophagy |
MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis. | |||
T36350 | Cho-Arg (trifluoroacetate salt) | ||
Cho-Arg is a steroid-based cationic lipid that contains a cholesterol skeleton coupled to an L-arginine head group. It forms a complex with plasmid DNA and decreases plasmid DNA migration in an agarose-gel retardant assa... | |||
T29233 | Z-LLNle-CHO | ||
Z-LLNle-CHO is a cell permeable inhibitor of gamma-secretase. Z-LLNle-CHO induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response. | |||
T36368 | 2H-Cho-Arg (trifluoroacetate salt) | ||
2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. It forms a complex with plasmid DNA (pDNA) and dec... | |||
T6583 | MG-101 | ALLN,Ac-LLnL-CHO,Calpain inhibitor I,Calpain inhibitor-1,MG101 | Cysteine Protease , Proteasome |
MG-101 (Calpain inhibitor I) is a cell-permeable and potent inhibitor of cysteine proteases including calpains and lysosomal cathepsins. | |||
T19883 | Ac-YVAD-CHO | L 709049,L-709049,L709049 | |
L 709049 is a biologically active compound that is a selective inhibitor of interleukin-1β converting enzyme (Caspase-1). Caspase inhibitors interfere with the initiation of apoptosis and have multiple clinical applicati... | |||
T80513 | YVAD-CHO | ||
YVAD-CHO is an inhibitor of interleukin-1β converting enzyme (ICE, caspase 1) that has been shown to partially mitigate motoneuron death in mice with lesioned facial nerves [1]. | |||
T80093 | IETD-CHO TFA | Caspase | |
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1]. | |||
T80076 | Ac-ESMD-CHO | Casein Kinase | |
Ac-ESMD-CHO functions as an inhibitor of both caspase-3 and caspase-7, specifically obstructing the proteolytic cleavage of the caspase-3 precursor peptide (CPP32) at the Glu-Ser-Met-Asp (ESMD) site [1] [2]. | |||
T78586 | Ac-IETD-CHO | Apoptosis | |
Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. Furthermore, this compound hampers cell death induced by cy... | |||
T80467 | Boc-AEVD-CHO | Caspase | |
Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2]. | |||
T78622 | Ac-VDVAD-CHO | Casein Kinase | |
Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1]. | |||
T80532 | Ac-AAVALLPAVLLALLAP-YVAD-CHO | Caspase | |
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1]. | |||
T80536 | Ac-AAVALLPAVLLALLAP-LEVD-CHO | Caspase | |
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1]. | |||
T73683 | AC-VEID-CHO TFA | ||
AC-VEID-CHO (TFA) is a peptide-derived inhibitor targeting Caspases-6, -3, and -7, exhibiting IC50 values of 16.2 nM, 13.6 nM, and 162.1 nM, respectively. This compound demonstrates significant inhibitory potency and is ... | |||
T80537 | Ac-AAVALLPAVLLALLAP-LEHD-CHO | Caspase | |
Ac-AAVALLPAVLLALLAP-LEHD-CHO is a caspase inhibitor targeting caspases 4, 5, and 9, demonstrating protective effects in MCF-7 cells treated with Neocarzinostatin [1]. | |||
T73852 | Ac-YVAD-CHO acetate | ||
Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1β converting enzyme (ICE) inhibitor, demonstrating specificity for caspase-1 as well. It exhibits K_i values of 3.0 nM in mic... | |||
T78619 | Z-Pro-Pro-CHO | Prolyl Endopeptidase (PREP) | |
Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01 μM for Schistosoma mansoni prolyl oligopeptidase [1]. | |||
T38240 | 2,6-Dichlorodiphenylamine | Antibacterial | |
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1... | |||
T17281 | Z-Ile-Leu-aldehyde | Z-IL-CHO,GSI-XII,γ-Secretase inhibitor XII | Others |
Z-Ile-Leu-aldehyde is an effective and competitive peptide aldehyde inhibitor of γ-secretase and notch. | |||
T8566 | AA92593 | Others | |
AA92593 has been used as a selective inhibitor of melanopsin. | |||
T3306 | PF-04418948 | PF 04418948,PF04418948 | Prostaglandin Receptor |
PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers... | |||
T0432 | Diclofenac diethylamine | Apoptosis , COX | |
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID). | |||
T1671 | Mirabegron | YM178 | Adrenergic Receptor |
Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome. | |||
T8991 | BMS986187 | Opioid Receptor | |
BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor. | |||
T9927 | Panitumumab | EGFR | |
Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR). | |||
T2667 | PIK-75 | Apoptosis , DNA-PK , PI3K | |
PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM). | |||
T0196 | Diclofenac | Diclofenacum,Voltaren | Apoptosis , COX |
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a... | |||
T1566 | Aripiprazole | OPC-14597 | 5-HT Receptor |
Aripiprazole (OPC-14597) is an antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a... | |||
T6905 | Netupitant | Ro 67-31898/000,CID 6451149 | Neurokinin receptor |
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). | |||
T6470 | Diclofenac Potassium | CGP-45840B,Cataflam,Voltfast | Apoptosis , Others , COX |
Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions. | |||
T1555 | Diclofenac sodium | GP 45840 | Apoptosis , COX |
Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt. | |||
T6140 | SB-334867 free base | SB334867A free base,SB-334867,SB 334867,SB334867 | OX Receptor |
SB-334867 free base (SB334867A free base) is a selective orexin-1 (OX1) receptor antagonist. | |||
T23386 | SR 142948 | Neurotensin Receptor | |
SR 142948 is a neurotensin (NT) receptor antagonist. | |||
T2287 | PIK-75 hydrochloride | PIK-75 HCl,PIK-75 | Apoptosis , DNA-PK , PI3K |
PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM in cell-free assays. | |||
T0456 | Cinchophen | Cinconal | COX |
Cinchophen (Cinconal), an analgesic drug, is utilized in treating gout. | |||
T2227 | Hemicholinium 3 | Hemicholinium-3,Hemicholine | Others , AChE |
Hemicholinium 3 is a potent and selective choline uptake blocker. | |||
T23109 | 3,5-Dinitrocatechol | Transferase | |
OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5214 | Cholesteryl linoleate | CE(18:2(9Z,12Z)),Cholesterol Linoleate,Linoleic Acid cholesteryl ester | Others , Endogenous Metabolite |
Cholesteryl linoleate (Linoleic Acid cholesteryl ester) is a cholesterol ester found in LDL. Cholesteryl linoleate is transferred to the plasma membrane of macrophages and CHO cells expressing 15-lipoxygenase (15-LO) via... | |||
T2968 | Hyodeoxycholic acid | NSC 60672,α-Hyodeoxycholic Acid,HDCA | FXR , Endogenous Metabolite , GPCR19 |
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia. | |||
T36585 | Isodeoxycholic Acid | isoDCA | Chloride channel , Antibacterial |
Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less... | |||
TN6902 | Cholesteryl formate | 3beta-Acetoxy-cholest-5-ene | |
Cholesteryl formate (3beta-Acetoxy-cholest-5-ene), the first compounds to be isolated from red algae, is a cholesteryl ester. | |||
T0408 | Dehydrocholic acid | Dehystolin,Felacrinos,Sanocholen,Decholin | Others |
Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid. | |||
T4727 | Taurolithocholic acid sodium salt | Sodium taurolithocholate | Others , Calcium Channel |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors. | |||
T22293 | Chondroitine sulfate | Chondroitine sulfate (From cattle) | Others |
Chondroitin sulfate is an important structural component of cartilage and has been used as a dietary supplement for the treatment of joint discomfort. | |||
T2918 | Cholesteryl Acetate | Cholesterin acetate,Cholesterol acetate,Acebrochol | Others |
Cholesteryl Acetate is a cholesterol ester obtained from the esterification of the hydroxyl group of cholesterol with acetic acid. It functions as a metabolite in the human body and is both a cholesterol ester and an ace... | |||
T19189 | Allocholic acid | Others | |
Allocholic acid is a fetal bile acid found in vertebrates and reappears during liver regeneration and carcinogenesis. It is also a potent and specific stimulant of the adult olfactory system. | |||
T8712 | 1-Palmitoyl-sn-glycero-3-phosphocholine | 1-Hexadecanoyl-sn-glycero-3-phosphocholine | Others |
1-Palmitoyl-sn-glycero-3-phosphocholine (1-Hexadecanoyl-sn-glycero-3-phosphocholine) is a phosphocholine for fluorescent probe design | |||
T14002 | 12-Ketodeoxycholic acid | Endogenous Metabolite | |
12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1]. | |||
T6S0659 | Rhynchophylline | Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin | Calcium Channel , NF-κB |
1. Rhynchophylline (Mitrinermine) can protect against ischemic damage, probably via regulating the Akt/mTOR pathway. 2. Rhynchophylline can protect against glutamate-induced neuronal death, can inhibit MA impairment in c... | |||
T29078 | Ursodeoxycholic acid sodium | UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium | FXR , Endogenous Metabolite , GPCR19 |
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it... | |||
T4070 | Glycocholic Acid Sodium Salt | Glycocholate Sodium,Sodium Glycocholate | Others |
Glycocholic Acid Sodium Salt (Sodium Glycocholate) is a conjugated bile salt and ionic biologic detergent. It is involved in the emulsification of fats. | |||
TN6715 | 7-Ketocholesterol | Others | |
7-Ketocholesterol is a metabolite of Cholesterol | |||
T7331 | Ursocholic acid | Endogenous Metabolite | |
Ursocholic acid, a bile acid found predominantly in bile of mammals. | |||
T13522 | 7-Ketolithocholic acid | 3α-Hydroxy-7-oxo-5β-cholanic acid | Endogenous Metabolite |
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and serves to suppress the production of endogenous bile acid and the secretion of biliary cholester... | |||
T0760 | Cholesterol | Cholesterin,Cholesteryl alcohol | Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR |
Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us... | |||
T6270 | Trichostatin A | TSA | HDAC |
Trichostatin A (TSA) is a natural derivative of diene isohydroxamic acids. Trichostatin A is a histone deacetylase inhibitor (IC50=1.8 nM) that is reversible and specific. Trichostatin A leads to the hyperacetylation of ... | |||
T2202 | Lithocholic acid | 3α-Hydroxy-5β-cholanic acid | Apoptosis , Others , FXR , Endogenous Metabolite , Autophagy |
Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is... | |||
T0700 | Ursodeoxycholic acid | UDCA,Ursodiol | Potassium Channel , Endogenous Metabolite |
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption. | |||
TN1569 | Deoxylapachol | Antifection , Antifungal | |
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevi... | |||
TWA2417 | Sodium taurocholate | Taurocholate Sodium | Others |
Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and... | |||
T13506 | 3β-Ursodeoxycholic acid | Isoursodeoxycholic acid | |
3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) is a bile acid. 3β-Ursodeoxycholic acid (administered orally has shown good tolerability and good intestinal absorption. 3β-Ursodeoxycholic acid can undergo enzymatic iso... | |||
TN5173 | Trichorabdal A | Antifection | |
Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori. | |||
TN2259 | Taurocholic acid | N-Choloyltaurine | TNF , PI3K |
Taurocholic acid (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathwa... | |||
TL0006 | Cichoric Acid | Dicaffeoyltartaric acid,Chicoric Acid | Reactive Oxygen Species , HIV Protease |
Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues. It also a class of cannabinomimetics with CB2 receptor-dependent and ... | |||
T2831 | Glycocholic acid | Glycocholate,cholylglycine | Others , Endogenous Metabolite |
Glycocholic acid (Glycocholate) is a bile acid with anticancer activity. Glycocholic acid targets against pump resistance-related and non-pump resistance-related pathways. | |||
T2744 | Methyl Cholate | Cholic acid methyl ester | Others |
Methyl Cholate (Cholic acid methyl ester) is the methyl form of cholic acid. Cholic acid is a major bile acid produced by the liver and synthesized from cholesterol. | |||
T5254 | Glycodeoxycholate Sodium | Sodium glycyldeoxycholate,Sodium glycodeoxycholate,Glycodeoxycholic acid sodium salt | Others , Endogenous Metabolite |
Glycodeoxycholate Sodium (Glycodeoxycholic acid sodium salt) induces Apoptosis in hepatocytes by a mechanism associated with DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes ex... | |||
T2A2481 | Taurochenodeoxycholic Acid | Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine | Apoptosis , TNF , Caspase , Endogenous Metabolite |
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. | |||
T8011 | 1,2-dioleoyl-sn-glycero-3-phosphocholine | DOPC | Others |
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) is a phospholipid containing the unsaturated long-chain (18:1) oleic acid inserted at the sn-1 and sn-2 positions. | |||
T4713 | Phosphorylcholine chloride calcium salt tetrahydrate | Phosphocholine chloride calcium salt tet,CalciuM Phosphorylcholine Tetrahydrate | Others , Endogenous Metabolite |
Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) is a small haptenic molecule, is found in a wide variety of organisms. Human hepatic tumors undergo an elevation in the conc... | |||
T6805 | Choline bitartrate | 2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium | Others , AChR |
Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcho... | |||
T4537 | Cholic acid sodium | SodiumCholate | HIV Protease , Endogenous Metabolite |
Cholic acid sodium (SodiumCholate) exhibits a strong spermicidal and antiviral [anti-human immunodeficiency virus (HIV)-1] activity. | |||
TN1641 | (-)-Fenchone | Others , Antioxidant , Antifungal | |
(-)-Fenchone is a bicyclic monoterpenoid widely distributed in plants and can be extracted from Foeniculum vulgare and Peumus boldus. (-)-Fenchone has a wide range of biological activities including antioxidant, wound he... | |||
T1317 | Cinchonidine | α-Quinidine,L-Cinchonidine | 5-HT Receptor , Serotonin Transporter , Parasite |
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine. | |||
T19124 | 3-Oxocholic acid | 3-Ketocholic acid | Endogenous Metabolite |
3-Oxocholic acid(3-Ketocholic acid) is the metabolite of bile acid and the main product of bile degradation by Clostridium perfringens in the intestine.3-Oxocholic acid is a steroid acid mainly found in the bile of mamma... | |||
T1039 | Choline chloride | Biocolina,Biocoline,Hepacholine | AChR |
Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in li... | |||
T1138 | Taurocholic acid sodium salt hydrate | Sodium taurocholate hydrate,Taurocholic Acid sodium hydrate | Others , Potassium Channel , Endogenous Metabolite |
Taurocholic acid sodium salt hydrate (Sodium taurocholate hydrate) is the product of conjugation of taurine with cholic acid. The sodium salt, the main ingredient of the bile of carnivorous animals, is used as a detergen... | |||
T5077 | Deoxycholic acid sodium salt | Sodium deoxycholate,Sodium Desoxycholate | Endogenous Metabolite , GPCR19 |
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. | |||
TN2349 | Taurodeoxycholate sodium salt | Sodium taurodeoxylate | Endogenous Metabolite |
Taurodeoxycholate sodium salt (Sodium taurodeoxylate) is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. and it inhibits various inflammatory... | |||
T5240 | Cholestenone | (+)-4-Cholesten-3-one | Others , Endogenous Metabolite |
Cholestenone ((+)-4-Cholesten-3-one) is an intestinal metabolite of Cholesterol. It shows an anti-obesity effect on animals. | |||
TN7235 | 4-methoxylonchocarpin | TNF , NF-κB | |
4-methoxylonchocarpin was isolated from the roots of Abrus precatorius as a potent anti-inflammatory compound. 4-methoxylonchocarpin inhibited NF-κB-activated TNF expression by inhibiting the binding of LPS to TLR4 in ma... | |||
T19514 | Phosphatidylcholines,soya | Soybean phosphatidylcholine | Others |
Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes. | |||
TJA2398 | Taurodeoxycholic acid sodium hydrate | Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt | Apoptosis , Caspase |
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat. | |||
TN2215 | Taurochenodeoxycholic acid sodium | Sodium taurochenodeoxycholate | Apoptosis , Endogenous Metabolite |
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and... | |||
T8043 | 5α-Cholestane | Endogenous Metabolite | |
5α-Cholestane belongs to the cholestane steroid class of compounds. | |||
T5259 | Glycochenodeoxycholic acid sodium salt | GCDCA,Sodium glycochenodeoxycholate | Apoptosis , Others , Endogenous Metabolite |
Glycochenodeoxycholic acid sodium salt (GCDCA) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environmen... | |||
T2S0142 | 4-Hydroxylonchocarpin | Isobavachromene | Others |
Isobavachromene is a natural product from Psoralea corylifolia | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01596 | Butyrylcholinesterase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Butyrylcholinesterase (BCHE), also known as cholinesterase or BuChE, is an enzyme defined as "pseudo" or "non-neuronal" cholinesterase. Butyrylcholinesterase (BCHE) is widely distributed in the nervous system as well as ... | |||
TMPY-01742 | Acetylcholinesterase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role... | |||
TMPY-04905 | Zika virus (ZIKV) (strain Zika SPH2016) ZIKV-E (Stem/anchor domain of flavivirus envelope glycoprotein E) protein (Fc) | ZIKV | HEK293 |
Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are con... | |||
TMPH-03613 | NblA Protein, Synechococcus elongatus, Recombinant (His & Myc) | Synechococcus elongatus | E. coli |
NblA Protein, Synechococcus elongatus, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00390 | MOMP Protein, Chlamydia trachomatis, Recombinant (His & Myc) | Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein ... | |||
TMPH-03182 | DTE Protein, Pseudomonas cichorii, Recombinant (His & Myc) | Pseudomonas cichorii | E. coli |
Catalyzes the epimerization of various ketoses at the C(3) position. It is able to interconvert D-tagatose and D-ribulose to D-sorbose and D-xylulose, respectively. The enzyme is also able to accept other ketopentoses su... | |||
TMPH-03234 | Acetylcholinesterase Protein, Rat, Recombinant (His) | Rat | E. coli |
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. | |||
TMPH-00220 | Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 th... | |||
TMPH-00026 | Catechol 1,2-dioxygenase Protein, Acinetobacter baylyi, Recombinant (His) | Actinia equina | E. coli |
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cardiac stimulation and hemolysis. Pore formation is a multi-step process that involves specific recognition of membrane sphin... | |||
TMPH-03645 | Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) | Trichosanthes kirilowii | E. coli |
Alpha-TCS Protein, Trichosanthes kirilowii, Recombinant (His) is expressed in E. coli. | |||
TMPH-03615 | Ribonuclease J Protein, Synechocystis sp., Recombinant (His & SUMO) | Synechocystis sp. | E. coli |
Ribonuclease J Protein, Synechocystis sp., Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00265 | Ferrochelatase, mitochondrial Protein, Bovine, Recombinant (His & Myc & SUMO) | Bovine | E. coli |
Catalyzes the ferrous insertion into protoporphyrin IX. | |||
TMPH-03703 | Zot Protein, Vibrio cholerae serotype O1, Recombinant (His) | Vibrio cholerae | E. coli |
Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens). | |||
TMPY-02309 | CHODL Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
CHODL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 48.9 kDa. Accession number: EDK98299.1 | |||
TMPY-02923 | Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc) | Human | HEK293 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 36.6 kDa. Accession number: P01215 | |||
TMPK-01188 | CHODL Protein, Human, Recombinant (hFc) | Human | HEK293 |
chondrolectin (CHODL) is commonly overexpressed in the majority of lung cancers, indicating a possible correlation between CHODL and metastasis of lung cancer cells. the expression of CHODL is significantly decreased in ... | |||
TMPJ-00744 | Toxin B Protein, Vibriocholerae, Recombinant | Vibrio cholerae | E. coli |
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring dir... | |||
TMPH-00389 | OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO) | Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein ... | |||
TMPH-03068 | OV16 Protein, Onchocerca volvulus, Recombinant (His) | Onchocerca volvulus | E. coli |
OV16 Protein, Onchocerca volvulus, Recombinant (His) is expressed in E. coli. | |||
TMPH-00017 | AcpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) | Acholeplasma laidlawii | E. coli |
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. | |||
TMPH-00757 | Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His) | Eschscholzia californica | E. coli |
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbo... | |||
TMPH-03605 | CHOD Protein, Streptomyces sp., Recombinant (GST) | Streptomyces sp. | E. coli |
CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli. | |||
TMPH-03614 | DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) | Synechococcus sp. | E. coli |
DNA photolyase Protein, Synechococcus sp., Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPH-00392 | Small-CRP Protein, Chlamydia trachomatis, Recombinant (His & SUMO) | Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the large cysteine-rich periplas... | |||
TMPY-02408 | CHODL Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CHODL Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 23.4 kDa. Accession number: EDK98299.1 | |||
TMPY-03006 | CHODL Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
CHODL Protein, Rat, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 48.9 kDa. Accession number: D3ZI86 | |||
TMPH-00393 | PGP3-D Protein, Chlamydia trachomatis, Recombinant (His) | Chlamydia trachomatis | Yeast |
pGP3-D Protein, Chlamydia trachomatis, Recombinant (His) is expressed in Yeast with N-terminal 10xHis tag. The predicted molecular weight is 30.3 kDa. Accession number: P0CE18 | |||
TMPY-02941 | CHODL Protein, Rat, Recombinant (His) | Rat | HEK293 |
CHODL Protein, Rat, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 23.3 kDa. Accession number: D3ZI86 | |||
TMPY-01693 | Butyrylcholinesterase Protein, Human, Recombinant (His) | Human | HEK293 |
Butyrylcholinesterase (BCHE), also known as cholinesterase or BuChE, is an enzyme defined as "pseudo" or "non-neuronal" cholinesterase. Butyrylcholinesterase (BCHE) is widely distributed in the nervous system as well as ... | |||
TMPH-03057 | Chorismate synthase Protein, Neurospora crassa, Recombinant (His) | Neurospora crassa | E. coli |
Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN. | |||
TMPH-02244 | Trichohyalin Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later b... | |||
TMPH-02413 | Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO) | LCMV | E. coli |
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induc... | |||
TMPH-00388 | Chaperonin GroEL Protein, Chlamydia trachomatis, Recombinant (His & SUMO) | Chlamydia trachomatis | E. coli |
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical... | |||
TMPY-00647 | Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) | Human | HEK293 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 11.6 kDa. Accession number: P01215 | |||
TMPH-02412 | Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc) | LCMV | E. coli |
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induc... | |||
TMPH-03644 | Hydrophobin-2/HFB2 Protein, Trichoderma reesei, Recombinant (His & SUMOstar) | Hypocrea jecorina | Yeast |
Hydrophobin-2/HFB2 Protein, Trichoderma reesei, Recombinant (His & SUMOstar) is expressed in Yeast. | |||
TMPH-00391 | MOMP Protein, Chlamydia trachomatis serovar L2, Recombinant (His & SUMO) | Chlamydia trachomatis serovar L2 | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein ... | |||
TMPH-03702 | MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) | Vibrio cholerae | E. coli |
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocy... | |||
TMPH-00394 | PGP3-D Protein, Chlamydia trachomatis, Recombinant (E. coli, His) | Chlamydia trachomatis | E. coli |
pGP3-D Protein, Chlamydia trachomatis, Recombinant (E. coli, His) is expressed in E. coli with N-terminal 6xHis tag. The predicted molecular weight is 31.9 kDa. Accession number: P0CE18 | |||
TMPY-04586 | Chorionic Gonadotropin/CGA Protein, Human, Recombinant | Human | HEK293 |
Chorionic Gonadotropin/CGA Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 10.2 kDa. Accession number: P01215 | |||
TMPY-02906 | CD16b Protein, Human, Recombinant (NA2,His) | Human | CHO |
CD16b Protein, Human, Recombinant (NA2,His) is expressed in CHO with His tag. The predicted molecular weight is 22.2 kDa. Accession number: O75015.2 | |||
TMPY-06121 | PLA2G15 Protein, Chinese hamster, Recombinant (His) | Chinese hamster | CHO |
PLA2G15 Protein, Chinese hamster, Recombinant (His) is expressed in CHO with His tag. The predicted molecular weight is 45 kDa. Accession number: G3HKV9-1 | |||
TMPY-06867 | Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein | VZV | CHO |
Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein is expressed in CHO. The predicted molecular weight is 85.17 kDa. | |||
TMPH-03026 | CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) | Mycoplasma pneumoniae | E. coli |
Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of... | |||
TMPK-00094 | GP1BB Protein, Human, Recombinant (hFc) | Human | HEK293 |
The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superf... | |||
TMPK-00903 | GP1BB Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
The glycoprotein (GP) Ib-IX complex is the receptor on platelet surfaces that mediates their adhesion to subendothelium. It comprises three polypeptides (GP Ib alpha, GP Ib beta, GP IX), each of which belongs to a superf... | |||
TMPY-03629 | Syntaxin 8 Protein, Human, Recombinant (His) | Human | HEK293 |
STX8, also known as syntaxin 8, directly interacts with HECTd3. STX8 forms the SNARE complex with syntaxin 7, vti1b and endobrevin. STX8 belongs to the syntaxin family. Members of this family are key molecules implicated... | |||
TMPY-02132 | LYPLA2 Protein, Human, Recombinant (His) | Human | E. coli |
Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from... |
Cat No. | Product Name | ||
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L5300 | Mitochondria-Targeted Compound Library | 830 compounds | |
A unique collection of 830 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; |