Search Result

Search Results for " cox-1 "

Targets

188

Compounds

Natural Products

1730

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10033	COX-2-IN-1		COX
	COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).		COX
T13263	COX/5-LO-IN-1	Atreleuton analog	COX
	COX/5-LO-IN-1 is a cyclooxygenase and 5-lipoxygenase (5-LO) inhibitor, and used for inflammatory and allergic disease states.		COX
T0432	Diclofenac diethylamine		Apoptosis , COX
	Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).		Apoptosis , COX
T0458	Indomethacin	Indocin,Indometacine,Indomethacine,Indometacin	Phospholipase , COX , PDE , Autophagy
	Indomethacin (Indometacin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor.		Phospholipase , COX , PDE , Autophagy
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
T0196	Diclofenac	Diclofenacum,Voltaren	Apoptosis , COX
	Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...		Apoptosis , COX
T6737	Zaltoprofen	CN100,Soleton	COX
	Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.		COX
T0448	(S)-(+)-Ibuprofen	Dexibuprofen,(S)-Ibuprofen	BCL , Thrombin , Cysteine Protease , COX , PPAR
	(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).		BCL , Thrombin , Cysteine Protease , COX , PPAR
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.		Apoptosis , COX
T6470	Diclofenac Potassium	CGP-45840B,Cataflam,Voltfast	Apoptosis , Others , COX
	Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.		Apoptosis , Others , COX
T9042	Teriflunomide impurity 3	4-Amino-N-(4-trifluoromethylphenyl)benzamide	COX
	Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).		COX
T22398	Phenidone	1-phenyl-3-pyrazolidinone	Lipoxygenase , COX
	Phenidone (1-phenyl-3-pyrazolidinone) is a dual inhibitor of cyclooxygenases and lipoxygenases that ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes[1]. The lipoxyg...		Lipoxygenase , COX
T23333	SC-58125	SC 58125	COX
	SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor, with an IC50 of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo, and it also can inhibit edema at the inflammatory site and is analgesic		COX
T62350	XO/COX/LOX-IN-1
	XO/COX/LOX-IN-1 is a potent inhibitor of xanthine oxidase/cyclooxygenase/lipoxygenase XO/COX/LOX. XO/COX/LOX-IN-1 can be used in the study of inflammatory, cancer and metabolic diseases.
T79594	COX-1/2-IN-5		COX
	COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity by inhibiting liver cancer HepG2...		COX
T61196	COX-1/2-IN-1
	COX-1/2-IN-2, a potent inhibitor of both COX-1 and COX-2, demonstrates significant inhibitory activity, with IC50 values of 13.9 ± 3.21 μM for COX-1 and 6.4 ± 0.74 μM for COX-2, respectively [1].
T36683	Vedaprofen	Quadrisol,PM 150,CERM 10202	COX , Antibacterial , Prostaglandin Receptor
	Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.		COX , Antibacterial , Prostaglandin Receptor
T60992	COX-1/2-IN-3
	COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].
T60630	COX/5-LOX-IN-1
	COX/5-LOX-IN-1 (compound 6b) is a potent COX/5-LOX dual inhibitor with the potential for inflammation diseases research. COX/5-LOX-IN-1 has IC50s of 1.07, 0.55, and 0.28 μM for COX-1, COX-2, and 5-LOX enzyme, respectivel...
T62103	COX-2/PI3K-IN-1
	COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).
T4646	TA-02		p38 MAPK , Autophagy
	TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.		p38 MAPK , Autophagy
T2569	Chlorotrianisene	tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but...
T62998	COX-2/15-LOX-IN-1
	COX-2/15-LOX-IN-1 (Compound 14) is a COX-2 and 15-lipoxygenase (15-LOX) inhibitor that acts on COX-1 (IC50: 10.65 μM), COX-2 (IC50: 0.075 μM) and 15-LOX (IC50: 2.98 μM). 25 has an anti-inflammatory effect.
T61939	Topo I/COX-2-IN-1
	Topo I/COX-2-IN-1 (1H-30) is a potent Topo I/COX-2 inhibitor with the IC50 of 0.24 μM and 4.42 μM for COX-2 and Topo I, respectively. Topo I/COX-2-IN-1 induces apoptosis and inhibits migration of cancer cells, shows anti...
T61865	COX-1/2-IN-2
	COX-1/2-IN-2 is a potent inhibitor of both COX-1 and COX-2, displaying significant inhibitory effects with IC50 values of 9.7 ± 0.09 μM for COX-1 and 4.6 ± 1.45 μM for COX-2, respectively [1].
T79592	COX-1/2-IN-4		COX
	COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2. Additionally, it demonstrates moderate anticancer activity, exhibiting IC50 values ...		COX
T60403	COX-2/NO-IN-1
	COX-2/NO-IN-1 is an orally active nitric oxide synthase (iNOS) and NO ( IC 50 of 3.52 μM) inhibitor as well as suppresses the expression of COX-2. COX-2/NO-IN-1 has anti-inflammatory effects and reduces pathological dama...
T63398	COX-2/sEH-IN-1
	COX-2/sEH-IN-1 is an orally active dual inhibitor of COX-2 (IC50: 1.24 μM) and sEH (IC50: 0.40 μM), a soluble epoxide hydrolase. COX-2/sEH-IN-1 increases anti-inflammatory effects and significantly reduces cardiovascular...
T61674	COX-2/5-LOX-IN-1
	COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent and dual inhibitor of COX-2 / 5-LOX. It exhibits superior analgesic and anti-inflammatory properties compared to Celec...
T22790	FR 122047	4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride,1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride	COX
	FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 µM for human recombinant COX-1 and COX-2, respectively...		COX
T5843L	(S)-Flurbiprofen	esflurbiprofen	COX , PGE Synthase
	Esflurbiprofen is an inhibitor of COX-1 and COX-2.		COX , PGE Synthase
T1582L	Naproxen sodium	Miranax,Anaprox,RS-3650,Naprelan	COX , Autophagy
	Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.		COX , Autophagy
T1212	Ketorolac tromethamine salt	Acular LS,Toradol,Ketorolac tris salt,Acular	COX
	Ketorolac tromethamine salt (Ketorolac tris salt) non-selective inhibits the enzymes cyclooxygenase 1 (COX-1) and COX-2with anti-inflammatory, analgesic, and antipyretic activities.		COX
T7662	α-Demethylnaproxen		COX
	α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)		COX
T8505	SC-236	Sc 236	Apoptosis , COX , PPAR
	SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).		Apoptosis , COX , PPAR
T0758	Piroxicam	CP-16171	COX
	Piroxicam (CP-16171) is a non-specific COX inhibitor.		COX
T0708	Oxaprozin	Oxaprozinum,Wy21743	NF-κB , COX
	Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compound...		NF-κB , COX
T8656	CAY10404	3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T	Apoptosis , Akt , COX
	CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel...		Apoptosis , Akt , COX
T4101	SC-560	SC560	COX
	SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.		COX
T7724	Tepoxalin	RWJ-20485,RWJ20485,ORF20485,ORF-20485,RWJ 20485,ORF 20485	Lipoxygenase , COX
	Tepoxalin (RWJ 20485) is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxyge...		Lipoxygenase , COX
T15181	DuP-697		COX
	DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic...		COX
T0463L	Loxoprofen sodium	CS-600,CS600,Loxoprofen,CS 600	COX
	Loxoprofen sodium (CS-600) is an effective and oral sodium inhibitor of COX-1 and COX-2 with IC50 of 6.5 and 13.5 μM, respectively. Loxoprofen sodium works by reducing the synthesis of prostaglandins from arachidonic aci...		COX
T7596	Firocoxib	ML 1785713	COX
	Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.		COX
T16817	S-2474		Lipoxygenase , COX
	S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits Abeta (25 - 35) and Abeta (1 - 40) induced cell death.		Lipoxygenase , COX
T0005	Aspirin	Acetylsalicylate,Acetylsalicylic Acid,ASA	Mitophagy , Virus Protease , COX , Autophagy
	Aspirin (Acetylsalicylic Acid) is a potent and selective inhibitor of COX with various pharmacological activities, such as anti-inflammation and pain relief. Aspirin is a histone deacetylase inhibitors to up-regulate cel...		Mitophagy , Virus Protease , COX , Autophagy
T6574	Lumiracoxib	Prexige,COX-189	COX
	Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.		COX
T1574	Etoricoxib	Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine	COX
	Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenas...		COX
T0826	Meloxicam	Movalis,Mobic,Metacam	Apoptosis , COX , Autophagy
	Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of meloxicam is as a Cyclooxygenase Inhibitor. The chemical classification of meloxicam is Nonsteroidal Anti-inflammatory Compounds.		Apoptosis , COX , Autophagy
T6424	Bromfenac Sodium	AHR 10282B,Bronuck,AHR 10282R	COX
	Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.		COX
T21412	Ketorolac	Toradol,Sprix,Acuvail,Macril,Acular	COX
	Ketorolac (Acuvail) is a non-steroidal anti-inflammatory drug (NSAID) in the family of heterocyclic acetic acid derivatives. It acts by inhibiting the bodily synthesis of prostaglandins.		COX

Compounds

Synonym: Atreleuton analog

Target: COX

Diclofenac diethylamine

T0432

Synonym:

Target: Apoptosis, COX

Indomethacin

T0458

Synonym: Indocin,Indometacine,Indomethacine,Indometacin

Target: Phospholipase, COX, PDE, Autophagy

Synonym: Diclofenacum,Voltaren

Target: Apoptosis, COX

Zaltoprofen

T6737

Synonym: CN100,Soleton

Target: COX

(S)-(+)-Ibuprofen

T0448

Synonym: Dexibuprofen,(S)-Ibuprofen

Target: BCL, Thrombin, Cysteine Protease, COX, PPAR

Diclofenac sodium

T1555

Synonym: GP 45840

Target: Apoptosis, COX

Diclofenac Potassium

T6470

Synonym: CGP-45840B,Cataflam,Voltfast

Target: Apoptosis, Others, COX

Teriflunomide impurity 3

T9042

Synonym: 4-Amino-N-(4-trifluoromethylphenyl)benzamide

Target: COX

Phenidone

T22398

Synonym: 1-phenyl-3-pyrazolidinone

Target: Lipoxygenase, COX

Synonym: Quadrisol,PM 150,CERM 10202

Target: COX, Antibacterial, Prostaglandin Receptor

Target: p38 MAPK, Autophagy

Chlorotrianisene

T2569

Synonym: tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, COX

Synonym: 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride,1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride

Target: COX

(S)-Flurbiprofen

T5843L

Synonym: esflurbiprofen

Target: COX, PGE Synthase

Naproxen sodium

T1582L

Synonym: Miranax,Anaprox,RS-3650,Naprelan

Target: COX, Autophagy

Ketorolac tromethamine salt

T1212

Synonym: Acular LS,Toradol,Ketorolac tris salt,Acular

Target: Apoptosis, COX, PPAR

Synonym: Oxaprozinum,Wy21743

Target: NF-κB, COX

CAY10404

T8656

Synonym: 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T

Target: Apoptosis, Akt, COX

Synonym: RWJ-20485,RWJ20485,ORF20485,ORF-20485,RWJ 20485,ORF 20485

Target: Lipoxygenase, COX

Synonym: CS-600,CS600,Loxoprofen,CS 600

Target: Lipoxygenase, COX

Aspirin

T0005

Synonym: Acetylsalicylate,Acetylsalicylic Acid,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Lumiracoxib

T6574

Synonym: Prexige,COX-189

Target: COX

Etoricoxib

T1574

Synonym: Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine

Target: COX

Meloxicam

T0826

Synonym: Movalis,Mobic,Metacam

Target: Apoptosis, COX, Autophagy

Bromfenac Sodium

T6424

Synonym: AHR 10282B,Bronuck,AHR 10282R

Target: COX

Ketorolac

T21412

Synonym: Toradol,Sprix,Acuvail,Macril,Acular

Target: COX

Cat No.	Product Name	Synonyms	Targets
T4S0590	Columbin		Phospholipase , COX , Parasite
	1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion.		Phospholipase , COX , Parasite
TQ0169	Inulicin	1-O-Acetylbritannilactone	FAK , NF-κB , COX , Src
	Inulicin (1-O-Acetylbritannilactone), an active compound isolated from Inula Britannica L, inhibits VEGF-mediated activation of Src and FAK.		FAK , NF-κB , COX , Src
T3883	Roburic acid		COX
	Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.		COX
T13597	(-)-Catechin	(-)-Catechuic acid,(-)-Cianidanol	COX
	(-)-Catechin ((-)-Cianidanol), an isomer of catechin, inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.		COX
TN1723	Hamaudol		COX
	Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.		COX
T2856	(-)-Epicatechin	L-Epicatechin,Epicatechin,(-)-Epicatechol	Ferroptosis , COX , Endogenous Metabolite
	(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.		Ferroptosis , COX , Endogenous Metabolite
T4643	TFAP	N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	COX , Endogenous Metabolite
	TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor		COX , Endogenous Metabolite
TN1377	α-Spinasterol	alpha-Spinasterol	COX , Antibacterial , TRP/TRPV Channel
	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 v...		COX , Antibacterial , TRP/TRPV Channel
T2S1625	(E)-Ethyl p-methoxycinnamate	Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC	Others , COX
	1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.		Others , COX
T2826	Asaraldehyde	Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde	COX
	Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1.		COX
T0065	Acetaminophen	4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol	COX , Endogenous Metabolite , Histone Acetyltransferase
	Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.		COX , Endogenous Metabolite , Histone Acetyltransferase
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T3342	Xanthohumol		Apoptosis , Others , Influenza Virus , COX , Acyltransferase , HSV
	Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows ...
T1468	Lornoxicam	Ro 13-9297,Chlortenoxicam,TS110	COX , Endogenous Metabolite
	Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co...		COX , Endogenous Metabolite
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T3915	Ginsenoside Ro	Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V	Calcium Channel , Reductase , Prostaglandin Receptor
	Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.		Calcium Channel , Reductase , Prostaglandin Receptor
T3868	Agnuside	chasteberry oil	COX , Prostaglandin Receptor , P-gp
	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce...		COX , Prostaglandin Receptor , P-gp
T6S1543	Dehydrodiisoeugenol		Others , NF-κB , COX , Antibacterial
	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated ...		Others , NF-κB , COX , Antibacterial
T6S0077	Byakangelicol		COX
	1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expr...		COX
T25253	Cinnamtannin B-1	Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358	Antioxidant , COX
	Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant a...		Antioxidant , COX
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T4A2456	Gamabufotalin	Gamabufagin	COX
	1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.		COX
T2759	Loganin	Loganoside	Apoptosis , NF-κB , BACE , AChR , AChE
	Loganin (Loganoside), an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent free-radical-scavenging activity and inhibitor...		Apoptosis , NF-κB , BACE , AChR , AChE
TN1622	Ermanin		NOS , Influenza Virus , COX , HIV Protease , Antibacterial , Antibiotic
	Ermanin is a flavonoid isolated from Tanacetum microphyllum.Ermanin inhibits platelet aggregation and has anti-tuberculosis and anti-viral/bacterial properties.Ermanin has anti-inflammatory activity by inhibiting the exp...
T5S1981	Alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...		Others , Endogenous Metabolite
T3S0645	N-trans-Feruloyltyramine	Feruloyltyramine,N-Feruloyltyramine,Moupinamide	Others , COX
	1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...		Others , COX
T3682	(-)-Catechin gallate	(-)-Catechin 3-O-gallate,(-)-Catechin 3-gallate	Others , COX
	(-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of 6PGD, IDH. (-)-Catechin gallate ((-)-Catechin 3-O-gallate) displays inhibition of human Beta-secretase. (-)-Catechin gallate ((-)-Catechin 3-O-gallat...		Others , COX
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T6S0413	Pectolinarigenin	Pectolinaringenin	Others , Lipoxygenase , COX
	1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in ...		Others , Lipoxygenase , COX
T6S1579	Monotropein	Monotropeine	Others
	1. Monotropein (Monotropeine) has antinociceptive action. 2. Monotropein has anti-apoptosis and anti-catabolic activity in chondrocytes. 3. Monotropein has anti-inflammatory action by inhibition of the expressions of inf...		Others
T2915	Bardoxolone	RTA 401,CDDO	Others , Nrf2
	Bardoxolone (CDDO) is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macrophages with an IC50 value of 0.4 nM. By supp...		Others , Nrf2
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T3S1553	Trans-Cinnamaldehyde	Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein	COX , Endogenous Metabolite
	1. trans-Cinnamaldehyde (Phenylacrolein) exhibits excellent anti-inflammatory activities and antidepressant-like effects in stressed mid-aged rats as a COX-2 inhibitor. 2. Cinnamic aldehyde induces apoptosis of CML cells...		COX , Endogenous Metabolite
T3417	Amentoflavone	Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin	Apoptosis , P450 , Phospholipase , Reactive Oxygen Species , Opioid Receptor , COX , Antibacterial , RSV , Antifungal
	Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhib...
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T2778	(+)-Catechin Hydrate		Antioxidant , COX
	(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems.		Antioxidant , COX
TN1420	Bacopaside I		Others
	Bacopaside I is a saponin isolated from Bacopa monniera. Bacopaside I is a modulator of Aquaporin-1 channel, has neuroprotective functions, it has anti-Alzheimer's disease, it ameliorates cognitive impairment in APP/PS1 ...		Others
T0822	Catechin	Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,Catechuic acid	Apoptosis , Influenza Virus , COX , Endogenous Metabolite
	Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.		Apoptosis , Influenza Virus , COX , Endogenous Metabolite
T4S2326	Cornuside	7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside	ERK , p38 MAPK , NF-κB , JNK
	1. Cornuside (Comuside) has immunomodulatory activity . 2. Cornuside suppresses expression levels of cytokine-induced proinflammatory and adhesion molecules in the human endothelial cells. 3. Cornuside can treat myocardi...		ERK , p38 MAPK , NF-κB , JNK
T2732	(-)-Epicatechin gallate	(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG	Virus Protease , COX , Autophagy
	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) is one of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin...		Virus Protease , COX , Autophagy
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
T7052	Gnetol		Tyrosinase , COX , HDAC , AChR
	Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...		Tyrosinase , COX , HDAC , AChR
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel
T6S1487	Ginsenoside Rg5		NF-κB , COX , IGF-1R
	1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer's disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ...		NF-κB , COX , IGF-1R
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T75625	Axinelline A
	Axinelline A, a potent inhibitor of cyclooxygenase (COX), demonstrates IC50 values of 2.22 μM for COX-2 and 8.89 μM for COX-1, indicating its higher affinity for COX-2. This compound exhibits anti-inflammatory activity [...
T10072	2-Hydroxy Ibuprofen	(±)-2-Hydroxy Ibuprofen	Others
	2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1/COX-2 (IC50s: 13 μM/370 μM).		Others
T79944	2-O-Sinapoyl makisterone A		COX
	Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively suppressing the expression of COX-2 protein [1].		COX
T1558	Resveratrol	trans-Resveratrol,SRT 501	Apoptosis , Mitophagy , IκB/IKK , Lipoxygenase , Sirtuin , COX , NADPH , DNA/RNA Synthesis , Nrf2 , Antibacterial , Antibiotic , Autophagy , Antifungal
	Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autop...
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Natural Products

Columbin

T4S0590

Synonym:

Target: Phospholipase, COX, Parasite

Inulicin

TQ0169

Synonym: 1-O-Acetylbritannilactone

Target: FAK, NF-κB, COX, Src

Synonym: (-)-Catechuic acid,(-)-Cianidanol

Synonym: L-Epicatechin,Epicatechin,(-)-Epicatechol

Target: Ferroptosis, COX, Endogenous Metabolite

TFAP

T4643

Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

Target: COX, Endogenous Metabolite

α-Spinasterol

TN1377

Synonym: alpha-Spinasterol

Target: COX, Antibacterial, TRP/TRPV Channel

(E)-Ethyl p-methoxycinnamate

T2S1625

Synonym: Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC

Target: Others, COX

Asaraldehyde

T2826

Synonym: Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde

Target: COX

Acetaminophen

T0065

Synonym: 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol

Target: COX, Endogenous Metabolite, Histone Acetyltransferase

Hexahydrocurcumin

TQ0288

Synonym:

Target: Reactive Oxygen Species, ROS, COX

Xanthohumol

T3342

Synonym:

Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV

Lornoxicam

T1468

Synonym: Ro 13-9297,Chlortenoxicam,TS110

Target: COX, Endogenous Metabolite

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

Ginsenoside Ro

T3915

Synonym: Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V

Target: Calcium Channel, Reductase, Prostaglandin Receptor

Agnuside

T3868

Synonym: chasteberry oil

Target: COX, Prostaglandin Receptor, P-gp

Dehydrodiisoeugenol

T6S1543

Synonym:

Target: Others, NF-κB, COX, Antibacterial

Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358

Target: Antioxidant, COX

Harpagoside

T6S2023

Synonym:

Target: Others, COX, NO Synthase

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Target: Apoptosis, NF-κB, BACE, AChR, AChE

Ermanin

TN1622

Synonym:

Target: NOS, Influenza Virus, COX, HIV Protease, Antibacterial, Antibiotic

alpha-Cyperone

T5S1981

Synonym: (+)-α-Cyperone,α-Cyperone

Target: Others, Endogenous Metabolite

N-trans-Feruloyltyramine

T3S0645

Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide

Target: Others, COX

(-)-Catechin gallate

T3682

Synonym: (-)-Catechin 3-O-gallate,(-)-Catechin 3-gallate

Target: Others, COX

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Pectolinarigenin

T6S0413

Synonym: Pectolinaringenin

Target: Others, Lipoxygenase, COX

Monotropein

T6S1579

Synonym: Monotropeine

Target: Others

Bardoxolone

T2915

Synonym: RTA 401,CDDO

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

trans-Cinnamaldehyde

T3S1553

Synonym: Cinnamaldehyde,Cinnamic aldehyde,Cinnamal,Phenylacrolein

Target: COX, Endogenous Metabolite

Amentoflavone

T3417

Synonym: Didemethyl-ginkgetin,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

(+)-Catechin Hydrate

T2778

Synonym:

Target: Antioxidant, COX

Synonym: Catechinic acid,D-Catechin,(+)-Catechin,Cianidanol,Catechuic acid

Target: Apoptosis, Influenza Virus, COX, Endogenous Metabolite

Cornuside

T4S2326

Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,Comuside

Target: ERK, p38 MAPK, NF-κB, JNK

(-)-Epicatechin gallate

T2732

Synonym: (−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG

Target: Virus Protease, COX, Autophagy

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

Gnetol

T7052

Synonym:

Target: Tyrosinase, COX, HDAC, AChR

8-Gingerol

T6S1684

Synonym:

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

Ginsenoside Rg5

T6S1487

Synonym:

Target: NF-κB, COX, IGF-1R

Jaceosidin

T3824

Synonym:

Target: Apoptosis, BCL, COX, UGT

Synonym: (±)-2-Hydroxy Ibuprofen

Target: Others

2-O-Sinapoyl makisterone A

Synonym: trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-01179	COX4I1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	COX4I1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPY-01736	COX-2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293

TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293
	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-00699	CD155/PVR Protein, Human, Recombinant (hFc)	Human	HEK293
	CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originall...
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-05239	HER2/ERBB2 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01226	CD4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre...
TMPY-01023	CD38 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05364	CD8 alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-02031	B7-H3 Protein, Human, Recombinant (His)	Human	HEK293
	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to ei...
TMPY-01050	Cadherin 6/CDH6 Protein, Human, Recombinant (His)	Human	HEK293
	Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-01608	Decorin Protein, Human, Recombinant (His)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
TMPY-02019	CD59 Protein, Human, Recombinant (His)	Human	HEK293
	CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membran...
TMPY-02099	CD63 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-05319	BCMA/TNFRSF17 Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-02034	Siglec-2/CD22 Protein, Human, Recombinant (His)	Human	HEK293
	CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. CD22 serves as an adhesi...
TMPY-05435	ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-04348	CTLA-4 Protein, Human, Recombinant (His)	Human	HEK293
	Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPY-05208	PD-L1 Protein, Human, Recombinant	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-01853	SIRP gamma Protein, Human, Recombinant (His)	Human	HEK293
	Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunog...
TMPY-01912	Cadherin 17/CDH17 Protein, Human, Recombinant (His)	Human	HEK293
	Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular r...
TMPY-04970	TIGIT Protein, Human, Recombinant (hFc)	Human	HEK293
	TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-01827	CD30/TNFRSF8 Protein, Human, Recombinant (His)	Human	HEK293
	CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of...
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His)	Human	HEK293
	Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-01851	CD73 Protein, Human, Recombinant (His)	Human	HEK293
	5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf...
TMPY-01462	IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, includi...
TMPY-01938	CD98 Protein, Human, Recombinant (His)	Human	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00991	LIFR Protein, Human, Recombinant (His)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-04949	PD-L1 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-04698	HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01305	OSMR Protein, Human, Recombinant (His)	Human	HEK293
	Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the typ...
TMPY-04826	LILRB5/CD85c Protein, Human, Recombinant (His)	Human	HEK293
	A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-03958	TGF alpha Protein, Human, Recombinant	Human	E. coli
	The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared...
TMPY-05016	HHLA2 Protein, Human, Recombinant (His)	Human	HEK293
	B7H7 gene encodes a protein-ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these ...
TMPY-02794	TLR2 Protein, Human, Recombinant (aa 1-587, His)	Human	Baculovirus-Insect Cells
	TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-03947	CD48 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481	IL-1R2 Protein, Human, Recombinant	Human	HEK293
	Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114	C-Reactive Protein /CRP Protein, Human, Recombinant (His)	Human	HEK293
	C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384	Src Protein, Human, Recombinant (His & GST)	Human	Baculovirus-Insect Cells
	Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151	MXRA8 Protein, Human, Recombinant (His)	Human	HEK293
	Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074	CD163 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPK-00383	ACE2/ACEH Protein, Human, Recombinant (His & Avi)	Human	HEK293
	ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02525	RGMA Protein, Human, Recombinant (His)	Human	HEK293
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
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