Search Result

Search Results for " cox-2 "

Targets

COX

258

Compounds

109

Natural Products

310

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T10032	COX-2-IN-2		COX
	COX-2-IN-2, a selective inducible COX2 inhibitor, exhibits potent inhibition with an IC50 of 0.24 μM. Meanwhile, COX-2-IN-1 functions as an anti-inflammatory agent, demonstrating both anti-inflammatory and analgesic acti...		COX
T10033	COX-2-IN-1		COX
	COX-2-IN-1 is a potent and selective COX-2 inhibitor (IC50: 3.9 μM).		COX
T77618	COX-2-IN-34		COX
	COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.		COX
T62061	COX-2-IN-6		COX , Prostaglandin Receptor
	COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 μM and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 μM.COX-2-IN-6 is u...		COX , Prostaglandin Receptor
T7207	FK 3311	FK-3311,COX-2 Inhibitor V	COX
	FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (NSAID)		COX
T0432	Diclofenac diethylamine		Apoptosis , COX
	Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).		Apoptosis , COX
T0458	Indomethacin	Indocin,Indometacine,Indomethacine,Indometacin	Phospholipase , COX , PDE , Autophagy
	Indomethacin (Indometacin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor.		Phospholipase , COX , PDE , Autophagy
T0196	Diclofenac	Diclofenacum,Voltaren	Apoptosis , COX
	Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...		Apoptosis , COX
T6737	Zaltoprofen	CN100,Soleton	COX
	Zaltoprofen (Soleton) is a Cox-1 and Cox-2 inhibitor, which is used for the treatment of arthritis.		COX
T0448	(S)-(+)-Ibuprofen	Dexibuprofen,(S)-Ibuprofen	BCL , Thrombin , Cysteine Protease , COX , PPAR
	(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).		BCL , Thrombin , Cysteine Protease , COX , PPAR
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.		Apoptosis , COX
T6470	Diclofenac Potassium	CGP-45840B,Cataflam,Voltfast	Apoptosis , Others , COX
	Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.		Apoptosis , Others , COX
T8356	FPL 62064		Lipoxygenase , COX
	FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin synthetase, respectively).		Lipoxygenase , COX
T22368	Metyrosine	α-Methyltyrosine	COX
	Metyrosine (α-Methyltyrosine) is an antihypertensive drug and could be used as a tyrosine hydroxylase inhibitor.Metyrosine significantly inhibits high COX-2 activity. Metyrosine is a very effective agent for blood pressu...		COX
T7596	Firocoxib	ML 1785713	COX
	Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.		COX
T7838	Losartan Carboxaldehyde		COX
	Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.		COX
T1562	Rebamipide	Proamipide,OPC12759	Free radical scavengers , COX , Prostaglandin Receptor
	Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...		Free radical scavengers , COX , Prostaglandin Receptor
T3214	NS-398	N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide,NS398	COX
	NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.		COX
T23333	SC-58125	SC 58125	COX
	SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor, with an IC50 of 0.04 μM. SC-58125 exhibits antitumor activity in vitro and in vivo, and it also can inhibit edema at the inflammatory site and is analgesic		COX
T79760	COX-2-IN-35		COX
	COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].		COX
T62175	COX-2-IN-8
	COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.
T61264	COX-2-IN-19
	COX-2-IN-19 (Compound 24) is a highly potent inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 1.76 μM. Notably, COX-2-IN-19 exhibits robust in vivo anti-inflammatory activity [1].
T61714	COX-2-IN-13
	COX-2-IN-13 (compound 13e) is a highly potent and selective inhibitor of COX-2, demonstrating a remarkable IC50 value of 0.98 μM. It exhibits strong anti-inflammatory activity and has shown favorable results in vivo acut...
T50005	Sertaconazole		Antifungal
	Sertaconazole is a broad-spectrum antifungal.		Antifungal
T78706	COX-2-IN-31		COX
	COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM). Additionally, it inhibits the activity of transmembrane hCA IX (Ki=48.9 nM) and hCA XII (Ki=5.8 nM). This...		COX
T78705	COX-2-IN-30		COX
	COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 = 10.4 μM), as well as 5-lipoxygenase (5-LOX; IC50 = 2.4 μM). ...		COX
T63480	COX-2-IN-26
	COX-2-IN-26 is a potent, orally active, selective COX-2 inhibitor that acts on COX-1 (IC50: 10.61 μM), COX-2 (IC50: 0.067 μM), and 15-LOX (IC50: 1.96 μM).COX-2-IN-26 is anti-inflammatory and has a gastrointestinal safety...
T63348	COX-2-IN-23
	COX-2-IN-23 is a selective inhibitor of COX-2, with IC50 values of 0.28 and 20.14 μM for COX-2 and COX-1, respectively.COX-2-IN-23 exhibits anti-inflammatory effects as well as low ulcerogenic effects.
T61711	COX-2-IN-14
	COX-2-IN-14 (compound 2a) is a highly potent and selective inhibitor of COX-2 (cyclooxygenase-2), with strong binding affinity at the active site of COX-2 co-crystal. Demonstrating remarkable in vivo anti-inflammatory ac...
T60978	COX-2-IN-7
	COX-2-IN-7 (compound 4a) is a potent, selective, and orally active COX-2 inhibitor which is higher selectivity than Celecoxib with an IC 50 value of 6.585 uM. COX-2-IN-7 has good anti-inflammatory and low ulcerogenic act...
T61821	COX-2-IN-16
	COX-2-IN-16 (compound 2b) is a potent, selective, and orally active inhibitor of cyclooxygenase-2 (COX-2) with an IC50 value of 102 μM. It effectively reduces nitric oxide (NO) production and demonstrates anti-inflammato...
T78754	COX-2-IN-33		COX
	COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent. It effectively suppresses pro-inflammatory cytokine production in vivo while ma...		COX
T79594	COX-1/2-IN-5		COX
	COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity by inhibiting liver cancer HepG2...		COX
T64109	COX-2-IN-28
	COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).
T63943	COX-2-IN-10
	COX-2-IN-10 is a potent inhibitor of COX-2. COX-2-IN-10 exhibits inhibitory effects on the production of IL-6, TNF-α and IL-1β. COX-2-IN-10 inhibits PGE2 production in a concentration-dependent manner with an IC50 value ...
T63646	COX-2-IN-9
	COX-2-IN-9 is a selective, potent, orally active COX-2 inhibitor (IC50: 10.17 μM).COX-2-IN-9 has a higher COX-2 selectivity than Celecoxib.COX-2-IN-9 exhibits good in vivo anti-inflammatory activity and low ulcerogenic e...
T60457	COX-2-IN-11
	COX-2-IN-11 (compound 7b2) is a potent and selective COX-2 inhibitor. COX-2-IN-11 has the potential in inflammation disease research[1].
T62259	COX-2-IN-21
	COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.
T63336	COX-2-IN-29
	COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).
T61760	COX-2-IN-18
	COX-2-IN-18 (Compound 3) is a highly effective COX-2 inhibitor with strong inhibitory activity against COX-2 (IC 50 = 0.775 μM). Its potency is comparable to the reference drug Celecoxib (IC 50 = 0.153 μM). This compound...
T60566	COX-2-IN-12
	COX-2-IN-12 (compound 3b) is a potent and selective COX-2 inhibitor with an IC 50 of 19.98 μM. COX-2-IN-12 is an anti-inflammatory agent that shows safety in-vivo acute toxicity studies [1].
T64063	COX-2-IN-24
	COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.
T60464	COX-2-IN-20
	COX-2-IN-20 (Compound 5d) is a selective and orally active inhibitor of COX-2 (IC 50 = 17.9 nM) with anti-inflammatory activity [1].
T62142	COX-2-IN-17
	COX-2-IN-17 is a potent, blood-brain barrier permeable COX-2 (cyclooxygenase-2) inhibitor (IC50: 0.02 μM) with anti-inflammatory and analgesic activity.
T79130	COX-2-IN-32		NF-κB
	COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression. Demonstrating anti-inflammatory properties, it impedes NO production in LPS-induced RAW264.7 macrophages with an IC...		NF-κB
T63215	COX-2-IN-22
	COX-2-IN-22 is a COX-2 inhibitor (IC50: 8.6 μM) that can cross the blood-brain barrier and also exhibits inhibitory effects on AChE (IC50: 2.8 μM), BChE (IC50: 6.3 μM), β-Secretase (IC50: 15.3 μM), LOX-5 (IC50: 13.9 μM) ...
T4646	TA-02		p38 MAPK , Autophagy
	TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.		p38 MAPK , Autophagy
T60769	COX-2/PI3K-IN-2
	COX-2/PI3K-IN-2 (compound 5f) has properties of anti-inflammatory and anti-cancer. COX-2/PI3K-IN-2 is a selective inhibitor of COX-2 (Ki = 3.02 nM) as well as a potent inhibitor of PI3K (IC 50 = 2.78 nM) [1].
T62241	Topo I/COX-2-IN-2
	Topo I/COX-2-IN-2 (Compound W10) is a potent dual Topo I (IC50: 0.90 μM) and COX-2 (IC50: 2.31 μM) inhibitor.Topo I/COX-2-IN-2 induces apoptosis in cancer cells using the mitochondrial pathway.
T79360	COX-2/15-LOX-IN-2		Lipoxygenase
	COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX. Additionally, it exhibits significant antioxidant activity [1].		Lipoxygenase

Compounds

Target: COX, Prostaglandin Receptor

FK 3311

T7207

Synonym: FK-3311,COX-2 Inhibitor V

Target: COX

Diclofenac diethylamine

T0432

Synonym:

Target: Apoptosis, COX

Indomethacin

T0458

Synonym: Indocin,Indometacine,Indomethacine,Indometacin

Target: Phospholipase, COX, PDE, Autophagy

Diclofenac

T0196

Synonym: Diclofenacum,Voltaren

Target: Apoptosis, COX

Zaltoprofen

T6737

Synonym: CN100,Soleton

Target: COX

(S)-(+)-Ibuprofen

T0448

Synonym: Dexibuprofen,(S)-Ibuprofen

Target: BCL, Thrombin, Cysteine Protease, COX, PPAR

Diclofenac sodium

T1555

Synonym: GP 45840

Target: Apoptosis, COX

Diclofenac Potassium

T6470

Synonym: CGP-45840B,Cataflam,Voltfast

Target: Apoptosis, Others, COX

FPL 62064

T8356

Synonym:

Target: Lipoxygenase, COX

Metyrosine

T22368

Synonym: α-Methyltyrosine

Losartan Carboxaldehyde

Synonym: Proamipide,OPC12759

Target: Free radical scavengers, COX, Prostaglandin Receptor

NS-398

T3214

Synonym: N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide,NS398

Target: p38 MAPK, Autophagy

Cat No.	Product Name	Synonyms	Targets
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T6S0413	Pectolinarigenin	Pectolinaringenin	Others , Lipoxygenase , COX
	1. Pectolinarigenin (Pectolinaringenin) exhibits hepatoprotective activity mainly via SOD antioxidant mechanism. 2. Pectolinarigenin possesses anti-inflammatory activity and that they may inhibit eicosanoid formation in ...		Others , Lipoxygenase , COX
T3399	Psoralidin		Others , Estrogen/progestogen Receptor , Reactive Oxygen Species , Lipoxygenase , Gamma-secretase , Akt , COX , Antibacterial
	Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally. Psoralidin possesses anticancer and chemopreventive properties.
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
TN2139	Regaloside B		NOS , COX , NO Synthase
	Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2).		NOS , COX , NO Synthase
T5758	Sphondin		COX , Prostaglandin Receptor
	Sphondin has anticonvulsant, anti-inflammatory, and anti-proliferative activities, it possessed an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells.		COX , Prostaglandin Receptor
T4643	TFAP	N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	COX , Endogenous Metabolite
	TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor		COX , Endogenous Metabolite
T0649	Salicylic acid	2-Hydroxybenzoic acid	Apoptosis , Mitophagy , COX , Endogenous Metabolite , Autophagy
	Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.
T1301	Guaiacol	O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol	NF-κB , COX , Endogenous Metabolite
	Guaiacol (2-Methoxyphenol) is a precursor to various flavorants, such as eugenol and vanillin. Its derivatives are used medicinally as an expectorant, antiseptic, and local anesthetic. It also can be used as an indicator...		NF-κB , COX , Endogenous Metabolite
T6S1572	Sauchinone		ERK , p38 MAPK , NF-κB
	1. Sauchinone is a useful adjunctive treatment for bacterial infection. 2. Sauchinone, an active lignan found in Saururus chinensis, to regulate the activation of HSCs, to prevent liver fibrosis, and to inhibit oxidative...		ERK , p38 MAPK , NF-κB
TN3500	Beta-Amyrone	β-Amyron	COX , AChR , PPAR , Antifection
	beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits a...		COX , AChR , PPAR , Antifection
T0399	Methyl salicylate	Gaultheria oil,Methyl 2-hydroxybenzoate,2-Carbomethoxyphenol,Betula oil,Natural wintergreen oil,Wintergreen oil	COX , TRP/TRPV Channel
	Methyl salicylate (Gaultheria oil) is an organic ester naturally produced by many species of plants, particularly wintergreens. For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic ...		COX , TRP/TRPV Channel
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T0335	Sodium salicylate	Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt	Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
	Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.		Apoptosis , NF-κB , COX , S6 Kinase , Autophagy
T5S2360	Corydaline	Corydalin,(+)-Corydaline	P450 , Virus Protease , Opioid Receptor , AChE
	1. Corydaline (Corydalin), an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastr...		P450 , Virus Protease , Opioid Receptor , AChE
T1633	β-Carotene	Carotaben,Beta-Carotene,Provitamin A	Apoptosis , ROS , Endogenous Metabolite
	β-Carotene (Provitamin A) is a naturally-occurring retinol (vitamin A) precursor obtained from certain fruits and vegetables with potential antineoplastic and chemopreventive activities. As an anti-oxidant, beta carotene...		Apoptosis , ROS , Endogenous Metabolite
T2826	Asaraldehyde	Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde	COX
	Asaraldehyde (2,4,5-trimethoxy-Benzaldehyde), a natural COX-2 inhibitor, exhibits 17-fold selectivity than COX-1.		COX
T3883	Roburic acid		COX
	Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.		COX
T0065	Acetaminophen	4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol	COX , Endogenous Metabolite , Histone Acetyltransferase
	Acetaminophen (APAP) is a COX inhibitor that inhibits COX-1 and COX-2 (IC50=113.7/25.8 μM). Acetaminophen has antipyretic and analgesic activity as well as weak anti-inflammatory activity.		COX , Endogenous Metabolite , Histone Acetyltransferase
T2972	Rutaecarpine	Rutacarpine,Rhetine,Rutecarpine	COX
	Rutaecarpine (Rhetine) is an inhibitor of COX-2 with IC50 of 0.28 μM.		COX
TN1723	Hamaudol		COX
	Hamaudol is a chromone isolated from Saposhnikovia divaricata,has analgesic and anti-inflammary activities, it showed inhibitory activity on COX-1 and COX-2 activities with values of 0.30, 0.57 mM, respectively.		COX
T3868	Agnuside	chasteberry oil	COX , Prostaglandin Receptor , P-gp
	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce...		COX , Prostaglandin Receptor , P-gp
TN1377	α-Spinasterol	alpha-Spinasterol	COX , Antibacterial , TRP/TRPV Channel
	α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 v...		COX , Antibacterial , TRP/TRPV Channel
T2S1625	(E)-Ethyl p-methoxycinnamate	Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC	Others , COX
	1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.		Others , COX
T4S0590	Columbin		Phospholipase , COX , Parasite
	1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion.		Phospholipase , COX , Parasite
T6S0722	Isoorientin	Homoorientin,Luteolin-6-C-glucoside	Antioxidant , COX
	Isoorientin (Homoorientin) has antioxidant activity.		Antioxidant , COX
T3747	Syringaldehyde	Syringic aldehyde,Springaldehyde	COX
	syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species like Manihot esculenta and Magnolia officinalis. Syringaldehyde moderately inhibits COX-2 activity wi...		COX
TQ0288	Hexahydrocurcumin		Reactive Oxygen Species , ROS , COX
	Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.		Reactive Oxygen Species , ROS , COX
T3342	Xanthohumol		Apoptosis , Others , Influenza Virus , COX , Acyltransferase , HSV
	Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows ...
T3039	Hederagenin	Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol	Others
	Hederagenin (Hederagenol) is a triterpenoid saponin inhibiting LPS-stimulated expression of iNOS, COX-2, and NF-κB.		Others
T5430	[8]-Shogaol	8-SHOGAOL	Apoptosis , COX
	[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.		Apoptosis , COX
TN7025	Canolol	Phenol, 4-ethenyl-2,6-dimethoxy-	COX
	Canolol (Phenol, 4-ethenyl-2,6-dimethoxy-) is an antioxidant phenolic compound that has potential use as a COX-2 inhibitor.		COX
T5759	S-(+)-Marmesin	(+)-Marmesin,(S)-Marmesin,marmesin	Lipoxygenase , COX
	S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.		Lipoxygenase , COX
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T1468	Lornoxicam	Ro 13-9297,Chlortenoxicam,TS110	COX , Endogenous Metabolite
	Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam co...		COX , Endogenous Metabolite
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
TN1373	α-Humulene	Alpha-caryophyllene	TNF , NOS , COX
	α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production an...		TNF , NOS , COX
T6S0077	Byakangelicol		COX
	1. Byakangelicol may inhibit P-gp expressed at the BBB even under in vivo conditions. 2. Byakangelicol can inhibit IL-1beta-induced PGE2 release in A549 cells; this inhibition may be mediated by suppression of COX-2 expr...		COX
T3811	Ginsenoside C-K	Ginsenoside compound K,Ginsenoside K	P450 , cell cycle arrest , COX , NO Synthase
	Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.		P450 , cell cycle arrest , COX , NO Synthase
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
T6S1543	Dehydrodiisoeugenol		Others , NF-κB , COX , Antibacterial
	1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated ...		Others , NF-κB , COX , Antibacterial
TQ0180	Chebulagic acid		SARS-CoV , Influenza Virus , Lipoxygenase , COX
	Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.		SARS-CoV , Influenza Virus , Lipoxygenase , COX
T6S2023	Harpagoside		Others , COX , NO Synthase
	1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression...		Others , COX , NO Synthase
T5431	[10]-Shogaol	10-Shogaol	Antioxidant , COX
	[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.		Antioxidant , COX
T5S1981	Alpha-Cyperone	(+)-α-Cyperone,α-Cyperone	Others , Endogenous Metabolite
	1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significantly inhibited PGE2 production by suppressing the LPS-induced...		Others , Endogenous Metabolite
T25253	Cinnamtannin B-1	Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358	Antioxidant , COX
	Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant a...		Antioxidant , COX
T5727	CAFESTOL		ERK , NF-κB , COX , PGE Synthase
	CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production...		ERK , NF-κB , COX , PGE Synthase
T4A2456	Gamabufotalin	Gamabufagin	COX
	1. Gamabufotalin (Gamabufagin) , a major bufadienolide of Chansu, has been used for treatment of COX-2-mediated diseases and cancer therapy due to its desirable metabolic stability and less adverse effect.		COX
TN1308	6-Hydroxyflavanone		Others , Lipoxygenase , COX , GABA Receptor
	6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A r...		Others , Lipoxygenase , COX , GABA Receptor
T5714	5-O-Demethylnobiletin	5-DEMETHYLNOBILETIN	Leukotriene Receptor , Lipoxygenase
	5-O-Demethylnobiletin (5-DEMETHYLNOBILETIN) is a natual product, has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2.		Leukotriene Receptor , Lipoxygenase
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Natural Products

Jaceosidin

T3824

Synonym:

Target: Apoptosis, BCL, COX, UGT

Pectolinarigenin

T6S0413

Synonym: Pectolinaringenin

Target: Others, Lipoxygenase, COX

Psoralidin

T3399

Synonym:

Target: Others, Estrogen/progestogen Receptor, Reactive Oxygen Species, Lipoxygenase, Gamma-secretase, Akt, COX, Antibacterial

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Regaloside B

TN2139

Synonym:

Target: NOS, COX, NO Synthase

sphondin

T5758

Synonym:

Target: COX, Prostaglandin Receptor

TFAP

T4643

Synonym: N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide

Target: COX, Endogenous Metabolite

Salicylic acid

T0649

Synonym: 2-Hydroxybenzoic acid

Target: Apoptosis, Mitophagy, COX, Endogenous Metabolite, Autophagy

Guaiacol

T1301

Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol

Target: NF-κB, COX, Endogenous Metabolite

Sauchinone

T6S1572

Synonym:

Target: ERK, p38 MAPK, NF-κB

beta-Amyrone

TN3500

Synonym: β-Amyron

Target: COX, AChR, PPAR, Antifection

Methyl salicylate

T0399

Synonym: Gaultheria oil,Methyl 2-hydroxybenzoate,2-Carbomethoxyphenol,Betula oil,Natural wintergreen oil,Wintergreen oil

Target: COX, TRP/TRPV Channel

Crocin II

T3779

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Sodium salicylate

T0335

Synonym: Salicylic acid sodium salt,2-Hydroxybenzoic acid sodium salt

Target: Apoptosis, NF-κB, COX, S6 Kinase, Autophagy

Corydaline

T5S2360

Synonym: Corydalin,(+)-Corydaline

Target: P450, Virus Protease, Opioid Receptor, AChE

β-Carotene

T1633

Synonym: Carotaben,Beta-Carotene,Provitamin A

Target: Apoptosis, ROS, Endogenous Metabolite

Asaraldehyde

T2826

Synonym: Asarylaldehyde,2,4,5-trimethoxy-Benzaldehyde,Asaronaldehyde

Synonym: 4-Acetamidophenol,4'-Hydroxyacetanilide,APAP,Paracetamol

Target: COX, Endogenous Metabolite, Histone Acetyltransferase

Rutaecarpine

T2972

Synonym: Rutacarpine,Rhetine,Rutecarpine

Synonym: chasteberry oil

Target: COX, Prostaglandin Receptor, P-gp

α-Spinasterol

TN1377

Synonym: alpha-Spinasterol

Target: COX, Antibacterial, TRP/TRPV Channel

(E)-Ethyl p-methoxycinnamate

T2S1625

Synonym: Ethyl para-methoxycinnamate,Ethyl 4-methoxycinnamate,4-Methoxycinnamic Acid Ethyl Ester,Ethyl methoxycinnamate,Ethyl p-methoxycinnamate,EPMC

Target: Others, COX

Columbin

T4S0590

Synonym:

Target: Phospholipase, COX, Parasite

Isoorientin

T6S0722

Synonym: Homoorientin,Luteolin-6-C-glucoside

Target: Antioxidant, COX

syringaldehyde

T3747

Synonym: Syringic aldehyde,Springaldehyde

Target: Reactive Oxygen Species, ROS, COX

Xanthohumol

T3342

Synonym:

Target: Apoptosis, Others, Influenza Virus, COX, Acyltransferase, HSV

Hederagenin

T3039

Synonym: Hederagenic acid,Astrantiagenin E,Caulosapogenin,Hederagenol

Target: Apoptosis, COX

Canolol

TN7025

Synonym: Phenol, 4-ethenyl-2,6-dimethoxy-

Target: COX

S-(+)-Marmesin

T5759

Synonym: (+)-Marmesin,(S)-Marmesin,marmesin

Target: Lipoxygenase, COX

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Lornoxicam

T1468

Synonym: Ro 13-9297,Chlortenoxicam,TS110

Target: COX, Endogenous Metabolite

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

α-Humulene

TN1373

Synonym: Alpha-caryophyllene

Target: TNF, NOS, COX

Synonym: Ginsenoside compound K,Ginsenoside K

Target: P450, cell cycle arrest, COX, NO Synthase

Ginsenoside Rb3

T3918

Synonym: Gypenoside IV

Target: NF-κB, COX, NO Synthase

Dehydrodiisoeugenol

T6S1543

Synonym:

Target: Others, NF-κB, COX, Antibacterial

Chebulagic acid

TQ0180

Synonym:

Target: SARS-CoV, Influenza Virus, Lipoxygenase, COX

Harpagoside

T6S2023

Synonym:

Target: Others, COX, NO Synthase

[10]-Shogaol

T5431

Synonym: 10-Shogaol

Target: Antioxidant, COX

alpha-Cyperone

T5S1981

Synonym: (+)-α-Cyperone,α-Cyperone

Target: Others, Endogenous Metabolite

Cinnamtannin B-1

T25253

Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358

Target: Antioxidant, COX

CAFESTOL

T5727

Synonym:

Target: ERK, NF-κB, COX, PGE Synthase

Target: Others, Lipoxygenase, COX, GABA Receptor

5-O-Demethylnobiletin

T5714

Synonym: 5-DEMETHYLNOBILETIN

Target: Leukotriene Receptor, Lipoxygenase

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01736	COX-2 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His)	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-02900	IL-17A Protein, Mouse, Recombinant	Mouse	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPY-02886	IL-17A Protein, Human, Recombinant	Human	E. coli
	IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions i...
TMPJ-00704	SCO1 Protein, Human, Recombinant (GST)	Human	E. coli
	Protein SCO1 Homolog, Mitochondrial (SCO1) is a member of the SCO1/2 family. SCO1 has a homodimer structure. SCO1 is located in mitochondrion and is highly expressed in muscle, heart, and brain. It is characterized by hi...
TMPJ-00776	HER2/ERBB2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPJ-00777	HER2/ERBB2 Protein, Human, Recombinant (aa 23-652, hFc)	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-02011	CD96 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-00871	LAYN Protein, Human, Recombinant (hFc)	Human	HEK293
	Layilin recently characterized as a 55 kDa transmembrane protein with homology to C-type lectins, is present in numerous cell lines and tissue extracts. As one of the adaptor proteins, talin mediates the interactions bet...
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His)	Human	HEK293
	FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ ...
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293
	Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neurotrophic factors: glial cell line-derived neurotrophic fact...
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149)	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00748	Nectin-2 Protein, Human, Recombinant	Human	HEK293
	Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-00005	FGF-8a Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	4F2 cell-surface antigen heavy chain, also known as 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, CD98, SLC3A2 and MDU1, is a single-pass type I I membrane protein that belongs to the SLC3A tr...
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293
	Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-04051	C-Kit Protein, Human, Recombinant (hFc)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-00392	PAM Protein, Human, Recombinant (His)	Human	HEK293
	Peptidylglycine alpha-amidating monooxygenase (PAM) is highly expressed in neurons and endocrine cells, where it catalyzes one of the final steps in the biosynthesis of bioactive peptides. PAM is also expressed in unicel...
TMPY-02432	VEGF164 Protein, Rat, Recombinant	Rat	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-04644	PDGFB Protein, Human, Recombinant (His)	Human	Yeast
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPY-02231	TrkB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-01717	VEGF164 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-05414	NKG2D/CD314 Protein, Mouse, Recombinant (hFc)	Mouse	Baculovirus-Insect Cells
	KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked type II transmembrane proteins with short intracellular protei...
TMPY-00747	Nectin-2 Protein, Human, Recombinant (His)	Human	HEK293
	Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein a...
TMPY-02500	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC c...
TMPY-01442	DMBT1 Protein, Human, Recombinant (His)	Human	HEK293
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB d...
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)	Human	HEK293
	Interleukin 5 receptor, alpha (IL5RA) also known as CD125 (Cluster of Differentiation 125) is a subunit of the Interleukin-5 receptor. IL5RA (CD125) is an interleukin 5 specific subunit of a heterodimeric cytokine recept...
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-01935	C-Kit Protein, Human, Recombinant (His)	Human	HEK293
	C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr...
TMPY-00751	TrkB Protein, Human, Recombinant (His)	Human	HEK293
	TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 (NTRK2) is a single transmembrane catalytic receptor with intracellular tyrosine kin...
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-02096	TACI Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B) also known as Transmembrane activator and CAML interactor (TACI) and CD267 antigen, is a member of the tumor necrosis factor receptor superfamily. TNFRSF...
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His)	Human	HEK293
	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagn...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	Human Cells
	ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc)	Human	HEK293
	CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPY-01199	CD74 Protein, Human, Recombinant (His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-05427	CD19 Protein, Human, Recombinant (hFc)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	K-Ras belongs to the small GTPase superfamily, Ras family. Like other members of the Ras family, K-Ras is a GTPase and is an early player in many signal transduction pathways. It is usually tethered to cell membranes bec...
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His)	Human	HEK293
	BTN3A1 has the structure of a type I receptor of the Ig superfamily and is part of a family of seven BTN receptors encoded by genes in the MHC. BTN molecules are composed of two Ig domains (IgV, IgC2), a single transmemb...
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