Search Result

Search Results for " cluster of differentiation antigen 135 "

Compounds

Cat No.	Product Name
T2340	AC1NS4RE		Tyrosinase
	It is a tyrosine kinase inhibitor.		Tyrosinase
T4428	CCT241736		Aurora Kinase , FLT
	CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resist...		Aurora Kinase , FLT
T6138	TCS 359	FLT3 Inhibitor	FLT
	TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.		FLT
T1938	FLT3-IN-2		FLT
	FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).		FLT
T2272	BPR1J-097	BPR1J097	FLT
	BPR1J-097 is a novel FLT-3 inhibitor(IC50: 11±7 nM) with promising in vivo anti-tumor activities. It also inhibits FLT-3...		FLT
T11298	FLT3-IN-3		FLT
	FLT3-IN-3 is an effective FLT3 inhibitor, and the IC50s of FLT3 WT and FLT3 D835Y are 13 and 8 nM, respectively.		FLT
T6756	AMG 925		CDK , FLT
	AMG 925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC50 of 1 nM and 3 nM, respectively.		CDK , FLT
T15335	FN-1501		FLT , CDK
	FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK...		FLT , CDK
T6020	Pacritinib	SB1518	FLT , Tyrosine Kinases , JAK
	Pacritinib (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).		FLT , Tyrosine Kinases , JAK
T2640	Rebastinib	DCC 2036,DCC2036,DCC-2036	Apoptosis , Bcr-Abl , FLT , Src
	DCC-2036 (Rebastinib) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 n...		Apoptosis , Bcr-Abl , FLT , Src
T7673	ATH686	ATH 686	FLT , Apoptosis
	ATH 686 is an potent and selective Inhibitor of FLT3.		FLT , Apoptosis
T16144	MRX-2843	UNC2371	Others , FLT
	MRX-2843 is a potent and orally active inhibitor of MERTK and FLT3(IC50s of 1.3 nM and 0.64 nM, respectively).		Others , FLT
T3065	TG101209		FLT , Apoptosis , Autophagy , JAK , c-RET
	TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.		FLT , Apoptosis , Autophagy , JAK , c-RET
T7007	UNC2025	UNC 2025,mrx-6313,UNC-2025	TAM Receptor , FLT
	UNC-2025（ IC50 of 0.74 nM and 0.8 nM） is a potent and orally bioavailable dual MER/FLT3 inhibitor. UNC-2025 is about 20-...		TAM Receptor , FLT
T6174	R406	R-406 besylate	Syk , Apoptosis , FLT
	R406 is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.		Syk , Apoptosis , FLT
T8317	5'-Fluoroindirubinoxime	5'-FIO	FLT
	5'-Fluoroindirubinoxime is a potent FLT3 inhibitor( IC50 : 15 nM).		FLT
T3455	Merestinib	LY2801653	ROS Kinase , FLT , c-Met/HGFR , ROS , Discoidin Domain Receptor (DDR)
	LY2801653 is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineo...
T6115	Fostamatinib	R788	Monoamine Transporter , Syk , FLT , Adenosine Receptor
	Fostamatinib(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on L...		Monoamine Transporter , Syk , FLT , Adenosine Receptor
T6350	CHIR-124	CHIR 124,CHIR124	Chk , Apoptosis , PDGFR , FLT , Src , GSK-3
	CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold...		Chk , Apoptosis , PDGFR , FLT , Src , GSK-3
T2677	Crenolanib	CP-868596,ARO 002	Autophagy , FLT , PDGFR
	Crenolanib is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM)...		Autophagy , FLT , PDGFR