T5399 |
GeA-69
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PARP
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GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays). |
T7318 |
Elimusertib
|
BAY-1895344 |
ATM/ATR
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BAY 1895344 is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.BAY 1895344 shows pote... |
T10406 |
Tuvusertib
|
ATR inhibitor 1,M1774 |
Others
,
ATM/ATR
,
Apoptosis
,
Chk
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Tuvusertib is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selectiv... |
T50098 |
TIQ-A
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PARP
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TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 ... |
T21320 |
Methoxyamine HCl
|
TRC-102,Methoxyamine,TRC102,TRC 102 |
Others
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|
Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER)... |
T4971 |
5'-DEOXYADENOSINE
|
5′-dAdo |
Endogenous Metabolite
|
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5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excell... |
T25839 |
MS0019266
|
MS 0019266,MS-0019266 |
|
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MS0019266 is a DNA damage repair inhibitor. |
T25838 |
MS0017509
|
MS 0017509,MS-0017509 |
|
|
MS0017509 is a DNA damage repair inhibitor. |
T10018 |
1-Methyladenine
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|
Others
|
|
1-Methyladenine is a DNA alkylation product that undergoes damage reversal through oxidative demethylation for repair pu... |
T14282 |
Amuvatinib hydrochloride
|
HPK 56 hydrochloride,MP470 hydrochloride |
Others
|
|
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with p... |
T69931 |
MFH290
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MFH290 is a novel cysteine (Cys)-directed covalent inhibitor of CDK12/13. MFH290 forms a covalent bond with Cys-1039 of ... |
T70873 |
M3541
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|
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M3541 is a potent, selective, orally active ATM inhibitor with potential chemo-/radio-sensitizing and antineoplastic act... |
T40345 |
AV-153
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AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand brea... |
T36701 |
Phosphoramide mustard (cyclohexanamine)
|
|
|
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Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphor... |
T26981 |
Ceralasertib formate
|
Ceralasertib,AZD-6738,AZD6738,AZD 6738 |
|
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Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selec... |
T63923 |
ATR-IN-5
|
|
|
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ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA dama... |
T75335 |
Ethylenediaminetetraacetic acid dipotassium dihydrate
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|
|
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Ethylenediaminetetraacetic acid (EDTA) dipotassium dihydrate is anticoagulants, chelating heavy metal and relieve toxici... |
T32189 |
Iproplatin
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Code name: JM9,JM 9,JM-9,CHIP |
|
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Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and f... |
T37729 |
IMP-1700
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IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin ... |
T75021 |
SZUH280
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SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC 50 of 0.58 μM in A549 cells. SZUH280 induces cancer ce... |