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Search Results for " dna damage/dna repair "

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Compounds

Cat No. Product Name
T5399 GeA-69 PARP
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
T7318 Elimusertib BAY-1895344 ATM/ATR
BAY 1895344 is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.BAY 1895344 shows pote...
T10406 Tuvusertib ATR inhibitor 1,M1774 Others , ATM/ATR , Apoptosis , Chk
Tuvusertib is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 µΜ) with selectiv...
T50098 TIQ-A PARP
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 ...
T21320 Methoxyamine HCl TRC-102,Methoxyamine,TRC102,TRC 102 Others
Methoxyamine HCl covalently binds to apurinic/apyrimidinic (AP) DNA damage sites and inhibits base excision repair (BER)...
T4971 5'-DEOXYADENOSINE 5′-dAdo Endogenous Metabolite
5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excell...
T25839 MS0019266 MS 0019266,MS-0019266
MS0019266 is a DNA damage repair inhibitor.
T25838 MS0017509 MS 0017509,MS-0017509
MS0017509 is a DNA damage repair inhibitor.
T10018 1-Methyladenine Others
1-Methyladenine is a DNA alkylation product that undergoes damage reversal through oxidative demethylation for repair pu...
T14282 Amuvatinib hydrochloride HPK 56 hydrochloride,MP470 hydrochloride Others
Amuvatinib hydrochloride (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with p...
T69931 MFH290
MFH290 is a novel cysteine (Cys)-directed covalent inhibitor of CDK12/13. MFH290 forms a covalent bond with Cys-1039 of ...
T70873 M3541
M3541 is a potent, selective, orally active ATM inhibitor with potential chemo-/radio-sensitizing and antineoplastic act...
T40345 AV-153
AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand brea...
T36701 Phosphoramide mustard (cyclohexanamine)
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphor...
T26981 Ceralasertib formate Ceralasertib,AZD-6738,AZD6738,AZD 6738
Ceralasertib is an orally available inhibitor of ataxia telangiectasia and rad3 related (ATR) kinase. Ceralasertib selec...
T63923 ATR-IN-5
ATR-IN-5 is a potent inhibitor of ATR, a member of the PIKK family of proteins involved in genome stability and DNA dama...
T75335 Ethylenediaminetetraacetic acid dipotassium dihydrate
Ethylenediaminetetraacetic acid (EDTA) dipotassium dihydrate is anticoagulants, chelating heavy metal and relieve toxici...
T32189 Iproplatin Code name: JM9,JM 9,JM-9,CHIP
Iproplatin is a synthetic second-generation platinum-containing compound related to cisplatin. Iproplatin binds to and f...
T37729 IMP-1700
IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin ...
T75021 SZUH280
SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC 50 of 0.58 μM in A549 cells. SZUH280 induces cancer ce...
GeA-69
T5399
synonym:
Target:
Elimusertib
T7318
synonym: BAY-1895344
Target:
Tuvusertib
T10406
synonym: ATR inhibitor 1,M1774
Target:
TIQ-A
T50098
synonym:
Target:
Methoxyamine HCl
T21320
synonym: TRC-102,Methoxyamine,TRC102,TRC 102
Target:
5'-DEOXYADENOSINE
T4971
synonym: 5′-dAdo
Target:
MS0019266
T25839
synonym: MS 0019266,MS-0019266
Target:
MS0017509
T25838
synonym: MS 0017509,MS-0017509
Target:
1-Methyladenine
T10018
synonym:
Target:
Amuvatinib hydrochloride
T14282
synonym: HPK 56 hydrochloride,MP470 hydrochloride
Target:
MFH290
T69931
synonym:
Target:
M3541
T70873
synonym:
Target:
AV-153
T40345
synonym:
Target:
Phosphoramide mustard (cyclohexanamine)
T36701
synonym:
Target:
Ceralasertib formate
T26981
synonym: Ceralasertib,AZD-6738,AZD6738,AZD 6738
Target:
ATR-IN-5
T63923
synonym:
Target:
Ethylenediaminetetraacetic acid dipotassium dihydrate
T75335
synonym:
Target:
Iproplatin
T32189
synonym: Code name: JM9,JM 9,JM-9,CHIP
Target:
IMP-1700
T37729
synonym:
Target:
SZUH280
T75021
synonym:
Target:
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