Search Result

Search Results for "dna��"

Libraries

DNA Damage and Repair Compound Library Plus DNA Damage & Repair Compound Library Methylation Compound Library Epigenetics Compound Library Transcription Factor-Targeted Compound Library Toxic Compound Library NF-κB Signaling Compound Library Cell Cycle Compound Library Chromatin Modification Compound Library Nuclear Receptor Compound Library Histone Modification Compound Library Ubiquitination Compound Library Mitochondria-Targeted Compound Library Antioxidant Compound Library Flavonoid Natural Product Library

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Reagents

SYBR Green qPCR Master Mix
(Low ROX)

Catalog No. C0008

SYBR Green qPCR Master Mix
(High ROX)

Catalog No. C0007

SYBR Green qPCR Master Mix
(No ROX)

Catalog No. C0006

Compounds

Cat No.	Product Name
T1507	Streptozocin	STZ , NSC-85998 , U 9889 , Streptozotocin	DNA Alkylation , DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
	Streptozotocin is an antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and ...
T9498	BAY-8400		DNA-PK
	BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM). BA...		DNA-PK
TQ0031	Nedisertib	M3814	DNA-PK
	Nedisertib (M3814) is a specific inhibitor of DNA-dependent Protein Kinase (DNA-PK, IC50: <3 nM).		DNA-PK
T60034	TH1085		Others
	TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (P...		Others
T15080	DC-05		DNA Methyltransferase , Histone Methyltransferase
	DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).		DNA Methyltransferase , Histone Methyltransferase
T14858	Calicheamicin	Calicheamicin γ1	Others
	Calicheamicin is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic compound that causes d...		Others
T2008	LY294002	NSC 697286 , SF 1101 , LY 294002	Casein Kinase , DNA-PK , Apoptosis , PI3K , Autophagy
	LY294002 is an inhibitor of PI3K (IC50s: 0.5/0.57/0.97 μM for PI3Kα/δ/β in cell-free assays). It also blocks autophagoso...		Casein Kinase , DNA-PK , Apoptosis , PI3K , Autophagy
T0974	Novobiocin Sodium	Albamycin , Cathomycin , Albamycinsodium	Potassium Channel , DNA gyrase , Topoisomerase , ABC , Antibacterial , Antibiotic , Autophagy
	Novobiocin binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic...
T9849	HQ461		CDK
	HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation, resulting in decreased C...		CDK
T0486	Irinotecan hydrochloride trihydrate	Irinotecan HCl Trihydrate , CPT-11 HCl Trihydrate	Topoisomerase , Autophagy
	Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.		Topoisomerase , Autophagy
T27029	Cjoc42	cjoc 42 , cjoc-42
	Cjoc42 is a inhibition of gankyrin, an ankyrin-repeat oncoprotein whose overexpression has been implicated in the develo...
T5840	Hoechst 33342	bisBenzimide H 33342 , HOE 33342	Autophagy
	Hoechst 33342, is a Benzimidazole fluorescent dye and a Cell permeable fluorescent DNA stain; binds minor groove of AT-r...		Autophagy
T27093	CT-1	CT 1	p53
	CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.		p53
TP2502	KYGVSVQDI Acetate		Others
	KYGVSVQDI Acetate is the DNA sequence encoding the MHC class I-restricted peptide p60(217-225) from Listeria monocytogen...		Others
T60028	MM41		DNA/RNA Synthesis
	MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 panc...		DNA/RNA Synthesis
TP1430	DTP3 TFA (1809784-29-9 free base)	DTP3 TFA	Others
	DTP3 TFA is a potent and selective GADD45β/MKK7 (growth arrest and DNA-damage-inducible β/mitogen-activated protein kina...		Others
T27613	InS3-54-A26		STAT
	inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the ...		STAT
T9275	ART558		DNA/RNA Synthesis
	ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM)....		DNA/RNA Synthesis
T38272	Thiacloprid		Parasite , AChR
	Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors ...		Parasite , AChR
TP1313L	Cecropin B acetate	Cecropin B acetate(80451-05-4 Free base)	P450 , Retinoid Receptor , Parasite
	Cecropin B acetate induces NF-κB activation and suppresses CYP3A29 by disrupting the association of the PXR/retinoid X r...		P450 , Retinoid Receptor , Parasite