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Search Results for " en4 "

Targets

7

Compounds

Cat No. Product Name Synonyms Targets
T9061 EN4 EN4 MYC inhibitor c-Myc
EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an...
T77525 EN450 NF-κB
EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be us...
T2249 XEN445 XEN 445,XEN-445 Lipase
XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties.
T15218 EN460 Others
EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation.
T15217 EN40 Others
EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).
TNU1263 N-1H-imidazo[4,5d   ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine
N-1H-imidazo[4,5d   ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine is a heterocyclic compound; intermediate and building block.
T24780 SEN461 SEN 461,SEN-461
SEN461 is a wnt inhibitor.
TargetMol