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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9061 | EN4 | EN4 MYC inhibitor | c-Myc |
EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an... | |||
T77525 | EN450 | NF-κB | |
EN450 is a cysteine-responsive covalent molecular gel degrader of targeted NF-κB with antiproliferative and potentially anticancer activity, which acts through a dependence on Cullin E3 ligase and protease, and can be us... | |||
T2249 | XEN445 | XEN 445,XEN-445 | Lipase |
XEN445, a potent and selective endothelial lipase(EL) inhibitor (IC50=0.237 uM), exhibitis good ADME and PK properties. | |||
T15218 | EN460 | Others | |
EN460 is an inhibitor of endoplasmic reticulum oxidation 1 (ERO1) and interacts selectively (IC50: 1.9 uM) with the reduced, active form of ERO1α and prevents its reoxidation. | |||
T15217 | EN40 | Others | |
EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM). | |||
TNU1263 | N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine | ||
N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine is a heterocyclic compound; intermediate and building block. | |||
T24780 | SEN461 | SEN 461,SEN-461 | |
SEN461 is a wnt inhibitor. |