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Compounds

Cat No.	Product Name
T3856	Tenuifoliside A		Others , ERK
	Tenuifoliside A has anti-apoptotic , neuroprotective activity. And tenuifoliside A has anti-inflammatory effect, which i...		Others , ERK
TMS2181	Trans-Zeatin	(E)-Zeatin	Endogenous Metabolite , ERK , MEK
	Trans-Zeatina is the member of the plant growth hormone family known as cytokinins, which regulate cell division, develo...		Endogenous Metabolite , ERK , MEK
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	Sphingosine-1-phosphate receptor 1 agonist SEW2871 prolongs heterotopic heart allograft survival in mice.		S1P Receptor , LPL Receptor
T35888	PB1
	PB1 is a potent intracellular disulfide reducing agent with several advantages including good cell permeability, the abi...
T8472	ERK1/2 inhibitor 2	ASTX029 , ASTX-029	ERK
	ASTX029 is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with ...		ERK
T3892	Isoacteoside	Isoverbascoside	NF-κB
	Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun...		NF-κB
T36672	CAY10561
	The extracellular signal-regulated kinase (ERK) signal transduction pathway regulates a diverse array of cellular proces...
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the preventio...		ERK
T6S1597	Mulberroside A		Tyrosinase , TNF , Interleukin
	1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbe...		Tyrosinase , TNF , Interleukin
TN2346	Mogrol		ERK , STAT , AMPK
	Mogrol is a biometabolite of mogrosides. Mogrol acts via inhibition of the ERK1/2 and STAT3 pathways, or reducing CREB a...		ERK , STAT , AMPK
T6066	SCH772984		ERK , MEK
	SCH 772984 is a potent inhibitor of ERK1/ERK2 (IC50: 4/1 nM) and has only weak inhibitory for other 300 tested kinases.		ERK , MEK
T14894	CC-90003		ERK
	CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.		ERK
TQ0005	KO-947		ERK
	KO-947 is a potent and specific inhibitor of ERK1/2 kinases.		ERK
T10479	BAY885		ERK
	BAY885 is a new ERK5 inhibitor.		ERK
T14360	AX-15836		ERK
	AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).		ERK
T6511	Ravoxertinib	GDC-0994	ERK
	GDC-0994 is an effective and orally available ERK1/2 inhibitor (IC50: 1.1/0.3 nM).		ERK
T6818	DEL-22379	DEL22379	ERK , Apoptosis
	DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.		ERK , Apoptosis
T10429	Tizaterkib	AZD-0364	ERK
	AZD-0364 is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1 (example 18; IC50: 0.6 nM).		ERK
T4091	Temuterkib	LY3214996	ERK
	LY-3214996 is a potent and selective, orally available inhibitor of the extracellular signal-regulated kinase (ERK) 1 an...		ERK
T1956	FR 180204	FR180204	Apoptosis , ERK
	FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.		Apoptosis , ERK