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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T13896 | Soya fatty acids | Others | |
Soya fatty acids is a class of polyunsaturated fatty acids isolated from soybean. | |||
T8642 | 4-CMTB | GPR | |
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38). | |||
T6043 | PF-3845 | FAAH , Autophagy | |
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2. | |||
T11557 | FASN-IN-3 | Fatty Acid Synthase | |
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN). | |||
T7947 | FT113 | Fatty Acid Synthase | |
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T28353 | PDP-EA | FAAH | |
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH. | |||
T17181 | TVB-3664 | Fatty Acid Synthase | |
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe... | |||
T7796 | TUG-1375 | GPR | |
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2 | |||
T15810 | LY2922470 | GPR | |
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava... | |||
T2684 | JNJ-1661010 | JNJ1661010,Takeda-25,JNJ 1661010 | FAAH |
JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2. | |||
T17180 | TVB-3166 | Apoptosis , Others , Fatty Acid Synthase | |
TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis,... | |||
T9967 | MAGL-IN-5 | Lipid | |
MAGL-IN-5 is a non-selective lipase inhibitor. | |||
T12580 | PTUPB | COX , Epoxide Hydrolase | |
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively). | |||
T21729 | (±)-Lisofylline | Others | |
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent. | |||
T7798 | FGH10019 | FGH-10019 | NPC1L1 , Fatty Acid Synthase |
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM). | |||
T3215 | JNJ-42165279 | JNJ42165279 | FAAH , Autophagy |
JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 re... | |||
T7688 | 4-Nonylphenylboronic acid | FAAH | |
4-Nonylphenylboronic acid is a inhibitor of FAAH. | |||
T8646 | URB937 | FAAH | |
URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM). | |||
T11458 | GPR40/FFAR1 modulator 1 | GPR | |
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator. | |||
T3433 | TUG-891 | TUG 891,TUG891 | GPR |
TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. | |||
T2351 | Fasiglifam | TAK875 | GPR |
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist. | |||
T4323 | PF-04457845 | PF04457845,PF 04457845 | FAAH , Autophagy |
PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM). | |||
T2601 | Vidofludimus | SC12267,4sc-101 | Dehydrogenase , DNA/RNA Synthesis , Interleukin |
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH). | |||
T29350 | 2-Hexyldecanoic acid | Pentadecane-7-carboxylic Acid,Isopalmitic Acid,7-Pentadecanecarboxylic acid,C16 Guerbet fatty acid,2-Hexyldecansaeure | |
2-Hexyldecanoic acid is a biochemical. | |||
T9808 | Tetradecylthioacetic acid | PPAR | |
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti... | |||
T7092 | NADPH tetrasodium salt | Others , Ferroptosis , Endogenous Metabolite | |
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an end... | |||
T2338 | JZL195 | FAAH , Lipase , Autophagy | |
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor. | |||
T11267 | FASN-IN-1 | TVB-2460 | Fatty Acid Synthase |
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt... | |||
T8927 | WWL 154 | WWL-154 | FAAH |
WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor. | |||
T4534 | BMS-309403 | FABP | |
BMS-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. | |||
T7482 | 3-chloro-5-hydroxybenzoic Acid | GPR | |
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM) | |||
TQ0020 | AMG 837 calcium hydrate | GPR | |
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM). | |||
T9722 | YTX-465 | Stearoyl-CoA Desaturase (SCD) | |
YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM). | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T15802 | LY2183240 | FAAH , Autophagy | |
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM). | |||
T7127 | DC260126 | Apoptosis , GPR | |
DC260126 is a small-molecule antagonist of FFA1 (GPR40) | |||
T1325 | Carprofen | Ridamyl,Imadyl,Rimadyl | FAAH , COX , Autophagy |
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. | |||
T3354 | BIA 10-2474 | BIA10-2474 | FAAH , Autophagy |
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o... | |||
T22027 | AH-7614 | AH 7614 | GPR |
AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist. | |||
T15413 | GPR120 Agonist 3 | GPR120-IN-1 | GPR |
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62). | |||
T4312 | GPR120 Agonist 2 | GPR120 receptor agonist | GPR |
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist. | |||
T7832 | Ibrolipim | NO-1886 | LPL Receptor |
Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway. | |||
T22967 | MEDICA16 | MEDICA 16 | GPR , Others , ATP Citrate Lyase |
MEDICA16 is a selective agonist for GPR40 as well as a partial agonist for GPR120. MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle with an increase in insu... | |||
T12437 | PF429242 dihydrochloride | S1P Receptor | |
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM). | |||
T1889 | CP-640186 | CP 640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | |||
T36841 | IPI-9119 | Fatty Acid Synthase | |
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM). | |||
T11256 | FAAH inhibitor 1 | Benzothiazole analog 3 | FAAH |
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM. | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T3171 | GSK137647A | GSK 137647 | GPR |
GSK137647A (GSK 137647) is a selective FFA4 agonist. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN4662 | Nonanal | Others | |
Nonanal is a growth factor for wood-rotting fungi. Nonanal is a potential attractant for the pine shoot beetle. | |||
TQ0260 | Cerulenin | Antibiotic , Antifungal , Fatty Acid Synthase | |
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus. | |||
T8276 | Methyl palmitoleate | Others | |
Palmitoleic acid methyl ester is an ester version of palmitoleic acid, an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | |||
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T8192 | Pentacosanoic acid | Others , Endogenous Metabolite | |
Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids. | |||
T14862 | Caprylic/Capric Triglyceride | Others | |
Caprylic/Capric Triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cos... | |||
T13719 | Hexadecanal | Palmitaldehyde | Endogenous Metabolite |
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals. | |||
T7529 | Yamogenin | Others | |
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek. | |||
T5567 | Tetradecanedioic acid | Tetradecanedicarboxylate | Others , Endogenous Metabolite |
Tetradecanedioic acid (Tetradecanedicarboxylate) is a long-chain fatty acid that is a type of endogenous metabolite. It can serve as a candidate biomarker for drug-drug interactions mediated by organic anion transporting... | |||
TN6953 | Lignoceric Acid | tetracosanoic acid | Endogenous Metabolite |
Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain. | |||
T2919 | Sesamin | Fagarol,Fsesamin | Others |
Sesamin (Fsesamin) is a lignan extracted from Sesamum indicum L. | |||
T10857 | Coenzyme A | Endogenous Metabolite | |
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine. | |||
T7967 | Methyl behenate | Others | |
Methyl behenate is a natural compound, is an ester form of docosanoic acid . | |||
T9512 | Linoleyl alcohol | CIS,CIS-9,12-OCTADECADIENOL | Others |
Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1]. | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
TJS0387 | Desoxyrhaponticin | Deoxyrhapontin,Deoxyrhaponticin | Apoptosis , Fatty Acid Synthase |
1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least... | |||
T2859 | Biochanin A | 4-Methylgenistein,Olmelin | EGFR , FAAH , Autophagy |
Biochanin A (4-Methylgenistein) is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor. | |||
T11590 | (-)-Hydroxycitric acid | Garcinia acid | ATP Citrate Lyase |
(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci... | |||
T7647 | Eicosadienoic acid | Endogenous Metabolite | |
Eicosadienoic acid is a rare, natural n-6 polyunsaturated fatty acid found mainly in animal tissues. | |||
T5368 | Eicosapentaenoic Acid | Histone Demethylase , Others , Endogenous Metabolite | |
Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms. | |||
TN1965 | N-Benzyllinolenamide | N-Benzyllinolenamide | FAAH , Autophagy |
N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM). | |||
T0846 | L-Carnitine | L(-)-Carnitine,Levocarnitine | Endogenous Metabolite , Fatty Acid Synthase |
L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz... | |||
T10024 | 1-Octanol | Octanol | Calcium Channel , Endogenous Metabolite |
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ... | |||
T7464 | 3,3-Dimethylglutaric acid | 3,3-Dimethylpentanedioate | Others , Endogenous Metabolite |
3,3-Dimethylglutaric acid (3,3-Dimethylpentanedioate) is a compound found in human urine. | |||
T12139 | N-(3-Methoxybenzyl)Palmitamide | FAAH | |
N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders. | |||
T3121 | Betulin | Trochol,betulinic alcohol,betuline,betulinol,Betulol | Apoptosis , Endogenous Metabolite , Lipid , Fatty Acid Synthase |
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is fo... | |||
T19180 | Adrenic Acid | cis-7,10,13,16-Docosatetraenoic acid | Endogenous Metabolite |
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a member of the class of compounds known as very-long-chain fatty acids. Adrenic Acid can be found in blood and in human myelin tissue. | |||
T3919 | Ginsenoside Rb2 | Ginsenoside C | GPR , Others , Influenza Virus , Endogenous Metabolite |
Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression. | |||
T3950 | Tridecanoic acid | n-Tridecoic Acid,n-Tridecanoic Acid,Tridecylic Acid | Others , Endogenous Metabolite , Antibacterial |
Tridecanoic acid (Tridecylic Acid) is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrate of phospholipase A2. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T3322 | Trans-Chalcone | Chalcone,Cinnamophenone,Chalkone | Apoptosis , Others , Antifungal , Fatty Acid Synthase |
trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. | |||
T19676 | Tributyrin | NSC661583,NSC 661583,NSC-661583 | Apoptosis |
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracell... | |||
T1286 | Vincamine | Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval | GPR , Others |
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. | |||
T4P2931 | Linoleic acid | 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid | Others , Endogenous Metabolite |
Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid. Prostaglandin precursor. | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
T3P2904 | α-Linolenic acid | Alpha-Linolenic Acid,Linolenic acid | Akt , PI3K |
α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland... | |||
T4859 | 1-Monomyristin | rac-Glycerol 1-myristate,Glyceryl myristate,Monomyristin,2,3-Dihydroxypropyl tetradecanoate | Others , FAAH , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal |
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloidal chemistr... | |||
TQ0251 | (Z)-2-decenoic acid | (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid | Others |
(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ... | |||
T4S1421 | Praeruptorin B | Praeruptorin D | NPC1L1 , Fatty Acid Synthase |
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway. | |||
T9514 | 1-Dodecanol | Endogenous Metabolite | |
1-Dodecanol is an endogenous metabolite and a saturated fatty alcohol from coconut oil fatty acids. It has a floral odor and is used in detergents, Lepidopteran pheromone/sex attractant, lubricating oils, pesticides and ... | |||
T18927 | Br-Mmc | 4-Bromomethyl-7-methoxycoumarin | Others |
Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is used as a new fluorescence label for fatty acids. It is used for the determination of fatty acids by HPLC or TLC. | |||
T5223 | Heneicosanoic acid | Heneicosylic Acid,C21:0 | Others , Endogenous Metabolite |
Heneicosanoic acid (C21:0) (HEA) is a fatty acid found in human milk fat. HEA is also a part of the phospholipids of the articular cartilage boundary lubricant. HEA is a constituent of red blood cell fatty acids. | |||
T4944 | Nervonic acid | cis-15-Tetracosenoic acid,Selacholeic acid | Endogenous Metabolite |
Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functio... | |||
T8032 | 4-Pentenoic acid | Others , Endogenous Metabolite | |
4-Pentenoic acid, also known as allyl acetic acid or 4-pentenate, belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain. 4-Pentenoic acid is ... | |||
T8049 | Pentadecanoic acid | Others , Endogenous Metabolite | |
Pentadecylic acid is a saturated fatty acid. | |||
T3949 | Myristic acid | Crodacid,Tetradecanoic acid,n-Tetradecanoic acid | Others , Endogenous Metabolite |
Myristic acid (Crodacid) , a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by covalently binding to the N... | |||
T5369 | Docosahexaenoic Acid | Cervonic acid,DHA | Others , Endogenous Metabolite |
Docosahexaenoic Acid (DHA) is an essential fatty acid and an omega-3 fatty acid abundant in brain and retina. | |||
T5246 | Trans-2-butene-1,4-dicarboxylic acid | trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid | Others , Endogenous Metabolite |
Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorde... | |||
T8271 | 10Z-Nonadecenoic acid | Endogenous Metabolite | |
10Z-Nonadecenoic acid is a long-chain fatty acid with anti-tumor activity. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-06686 | FASN Protein, Mouse, Recombinant (His) | Mouse | E. coli |
TMPJ-01073 | FABP5 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPY-06683 | FASN Protein, Human, Recombinant (His) | Human | E. coli |
TMPJ-00785 | FABP3 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in... | |||
TMPH-00933 | ADTRP Protein, Human, Recombinant (His & Myc) | Human | in vitro E. coli expression system |
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system. | |||
TMPJ-00671 | FABP7 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPY-02051 | FABP2 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP... | |||
TMPY-01878 | L-FABP Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid bindi... | |||
TMPY-01482 | FABP4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalyc... | |||
TMPY-02174 | FABP5 Protein, Human, Recombinant | Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic... | |||
TMPY-00605 | FABP3 Protein, Mouse, Recombinant | Mouse | E. coli |
Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular s... | |||
TMPH-03519 | ACP Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | Yeast |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPY-02239 | FABP3 Protein, Human, Recombinant | Human | E. coli |
Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular s... | |||
TMPY-02103 | FABP4 Protein, Human, Recombinant (29 Ala/Thr, His) | Human | E. coli |
Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to thecalyc... | |||
TMPH-03520 | ACP Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPY-03276 | BLBP Protein, Human, Recombinant | Human | E. coli |
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic l... | |||
TMPH-00572 | ACP Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. | |||
TMPH-03518 | ACP Protein, S. aureus, Recombinant (GST) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. | |||
TMPH-03431 | ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPH-03432 | ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
TMPH-03448 | EHT1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by est... | |||
TMPY-02249 | FABP6 Protein, Human, Recombinant | Human | E. coli |
Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to t... | |||
TMPJ-00292 | CD36 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ... | |||
TMPH-02764 | ACSL4 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli. | |||
TMPH-02825 | ACOX1 Protein, Mouse, Recombinant (Myc) | Mouse | E. coli |
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing ch... | |||
TMPH-00160 | Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) | Bacillus megaterium | E. coli |
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00955 | ALOX12 Protein, Human, Recombinant (His) | Human | E. coli |
ALOX12 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00529 | FABP6 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine ... | |||
TMPY-02481 | ACOX1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ... | |||
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 |
Carboxylesterase 2 (CES2) is a member of the carboxylesterase family and belongs to the multigene family. Carboxylesterase 2 is responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and... | |||
TMPH-03524 | KAS III Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may ther... | |||
TMPK-00795 | Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits. | |||
TMPK-00764 | Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits. | |||
TMPH-01780 | SCP2 Protein, Human, Recombinant (GST) | Human | E. coli |
Plays a crucial role in the peroxisomal oxidation of branched-chain fatty acids. Catalyzes the last step of the peroxisomal beta-oxidation of branched chain fatty acids and the side chain of the bile acid intermediates d... | |||
TMPH-01634 | MLYCD Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid syn... | |||
TMPH-00889 | FADS2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fa... | |||
TMPH-02692 | PLA2G15 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Has dual calcium-independent phospholipase and O-acyltransferase activities with a potential role in glycerophospholipid homeostasis and remodeling of acyl groups of lipophilic alcohols present in acidic cellular compart... | |||
TMPH-02618 | CYP2E1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr... | |||
TMPH-03755 | Ppard Protein, Human, Recombinant (His) | Human | E. coli |
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosape... | |||
TMPJ-00834 | ACADM Protein, Human, Recombinant (His) | Human | E. coli |
Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the m... | |||
TMPH-00565 | FabB Protein, E. coli, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can also use unsaturated fatty acids. Catalyz... | |||
TMPH-01325 | FAAH2 Protein, Human, Recombinant (His) | Human | in vitro E. coli expression system |
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatt... | |||
TMPY-01140 | ACOT13/THEM2 Protein, Human, Recombinant (His) | Human | E. coli |
The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ... | |||
TMPH-02822 | PNLIP Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activ... | |||
TMPH-01806 | OBP2A Protein, Human, Recombinant (C114S & K127N, His & SUMO) | Human | E. coli |
Probably binds and transports small hydrophobic volatile molecules with a higher affinity for aldehydes and large fatty acids. | |||
TMPH-02491 | SCD1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the Delta-9... | |||
TMPH-01626 | LIPA Protein, Human, Recombinant (GST) | Human | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. | |||
TMPH-03711 | PPAR gamma Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcript... | |||
TMPH-01850 | PNPLA2 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol ba... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L2510 | Lipid Metabolism Compound Library | 496 compounds | |
A unique collection of 496 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L2540 | Gut Microbial Metabolite Library | 614 compounds | |
A unique collection of 614 gut microbial metabolites which can be used for HTS and HCS; |