T3S0012 |
Coniferyl ferulate
|
|
P-gp
,
GST
|
|
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It s... |
T11240 |
Ethacrynic acid D5
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|
Others
|
|
Ethacrynic acid also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airw... |
TN5166 |
Trans-Methylisoeugenol
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|
5-HT Receptor
|
|
(E)-Methyl isoeugenol (trans-Methylisoeugenol) is a natural food flavour, it also has anxiolytic and antidepressant like... |
T2S1778 |
DL-Goitrin
|
Goitrin |
Others
|
|
1. Goitrin is a potent antithyroid compound found naturally in crucifers. 2. Goitrin is responsible for the induction of... |
T11505 |
GSTO1-IN-1
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|
Glutathione Peroxidase
,
GST
|
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GSTO1-IN-1 is a potent glutathione S-transferase omega 1 inhibitor (GSTO1; IC50: 31 nM). |
T3S0541 |
Curzerene
|
|
Apoptosis
,
GST
|
|
Curzerene is a sesquiterpene is isolated from the rhizome of Curculigo orchioides Gaertn with anti-cancer activity. Curz... |
T5097 |
Ezatiostat
|
TLK199 , TER199(free base) |
Apoptosis
,
Glutathione Peroxidase
,
GST
|
|
Ezatiostat is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity. |
TN1078 |
Seneciphylline
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P450
,
GST
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Seneciphylline, one of the hepatotoxic pyrolizidine alkaloids, has mutagenic activity in Drosophila and their transfer i... |
T4564 |
Ethacrynic acid
|
Etacrynic Acid , Edecrin , Hydromedin |
Calcium Channel
,
NF-κB
,
Others
,
GST
|
|
Ethacrynic acid is a nonsulfonamide loop diuretic that inhibits the activity of the Na+/K+/2Cl- cotransporter NKCC2 in t... |
T22776 |
Ezatiostat hydrochloride
|
TER199 , TLK199 HCl |
Glutathione Peroxidase
|
|
Ezatiostat hydrochloride is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glu... |
T7995 |
α-Angelica lactone
|
Alpha-Angelica Lactone |
Others
,
GST
|
|
Alpha-Angelica Lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent... |