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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11630 | IFN alpha-IFNAR-IN-1 hydrochloride | Others , IFNAR | |
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM. | |||
T11630L | IFN alpha-IFNAR-IN-1 | Others | |
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM). | |||
T13736 | Interferon receptor inducer-1 | IFNAR | |
Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer. | |||
T14687 | Deucravacitinib | BMS-986165 | Tyrosine Kinases , JAK , IFNAR , Interleukin |
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi... | |||
T12933 | SM-276001 | TLR , COX | |
SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer. | |||
T5317 | Cridanimod | CMA,XBIO-101,10-carboxymethyl-9-acridanone | Progesterone Receptor , STING , IFNAR |
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. | |||
T4403 | AX-024 hydrochloride | AX-024 HCl | IL Receptor , TNF , COX , IFNAR , Interleukin |
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A. | |||
T7081 | CCCP | Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone | Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial |
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ... | |||
T22142 | RO8191 | RO4948191,CDM-3008 | HCV Protease , HBV , JAK , IFNAR , STAT |
RO8191 (CDM-3008) (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor. | |||
T6273 | Vadimezan | DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 | Influenza Virus , VDA , STING , IFNAR |
Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan(NSC 640488) induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide... | |||
T78263 | Anti-Mouse IFNAR1 Antibody (MAR1-5A3) | IFNAR | |
Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. It is of the Mouse IgG1 kappa isotype and a corresponding i... | |||
T38161 | STING Agonist C11 | STING Agonist C11 | |
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3829 | Ginsenoside F3 | Others , IFNAR , Interleukin | |
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02647 | IFNAR1 Protein, Human, Recombinant (His) | Human | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPY-01489 | IFNAR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPK-00343 | IFNAR1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-00326 | IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-00342 | IFNAR1 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPK-00325 | IFNAR1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ... | |||
TMPY-02634 | IFNAR1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPK-00889 | IFNAR2 Protein, Human, Recombinant (aa 27-243, His) | Human | HEK293 |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated... | |||
TMPK-00637 | IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) | Cynomolgus | HEK293 |
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated... | |||
TMPY-04799 | IFNAR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei... | |||
TMPY-03829 | IFNAR1 Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPJ-00331 | IFNAR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus macaque | Human Cells |
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-... | |||
TMPH-02732 | IFNAR2 Protein, Mouse, Recombinant (His) | Mouse | Yeast |
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | |||
TMPY-01642 | IFNAR2 Protein, Human, Recombinant (His) | Human | HEK293 |
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei... | |||
TMPY-04254 | IFNAR1 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPY-03927 | IFNAR1 Protein, Rhesus, Recombinant | Rhesus | HEK293 |
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote... | |||
TMPY-01640 | IFNAR2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei... | |||
TMPY-00139 | IFNAR2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei... |