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Search Results for " ifnar "

Targets

12

Compounds

1

Natural Products

18

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T11630 IFN alpha-IFNAR-IN-1 hydrochloride Others , IFNAR
IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR. IFN alpha-IFNAR-IN-1 hydrochloride inhibits MVA-induced IFN-α responses by BM-pDCs with IC50 of 2-8 μM.
T11630L IFN alpha-IFNAR-IN-1 Others
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM).
T13736 Interferon receptor inducer-1 IFNAR
Interferon receptor inducer-1 Used in the treatment of a disorder in which the induction of interferon is involved. is an interferon (IFN) receptor inducer.
T14687 Deucravacitinib BMS-986165 Tyrosine Kinases , JAK , IFNAR , Interleukin
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...
T12933 SM-276001 TLR , COX
SM-276001 is a potent selective agonist of TLR7,and is an orally active interferon (IFN) inducer.
T5317 Cridanimod CMA,XBIO-101,10-carboxymethyl-9-acridanone Progesterone Receptor , STING , IFNAR
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
T4403 AX-024 hydrochloride AX-024 HCl IL Receptor , TNF , COX , IFNAR , Interleukin
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
T7081 CCCP Carbonyl Cyanide m-Chlorophenylhydrazone,Carbonyl cyanide 3-chlorophenylhydrazone Apoptosis , IκB/IKK , COX , Mitochondrial Metabolism , STING , IFNAR , Antibacterial
CCCP (Carbonyl Cyanide m-Chlorophenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. CCCP inhibits the activation of STING and its downstream signaling molecules ...
T22142 RO8191 RO4948191,CDM-3008 HCV Protease , HBV , JAK , IFNAR , STAT
RO8191 (CDM-3008) (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.
T6273 Vadimezan DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404 Influenza Virus , VDA , STING , IFNAR
Vadimezan (NSC 640488) is a fused tricyclic analogue of flavone acetic acid with potential antineoplastic activity. Vadimezan(NSC 640488) induces the cytokines tumor necrosis alpha (TNF-alpha), serotonin and nitric oxide...
T78263 Anti-Mouse IFNAR1 Antibody (MAR1-5A3) IFNAR
Anti-Mouse IFNAR1 Antibody (MAR1-5A3) is a neutralizing monoclonal antibody that specifically binds to IFNAR1, blocking its signaling both in vitro and in vivo. It is of the Mouse IgG1 kappa isotype and a corresponding i...
T38161 STING Agonist C11 STING Agonist C11
STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphory...
Cat No. Product Name Synonyms Targets
T3829 Ginsenoside F3 Others , IFNAR , Interleukin
Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02647 IFNAR1 Protein, Human, Recombinant (His) Human HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-01489 IFNAR1 Protein, Mouse, Recombinant (His) Mouse HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPK-00343 IFNAR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00326 IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00342 IFNAR1 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPK-00325 IFNAR1 Protein, Human, Recombinant (His & Avi) Human HEK293
IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits ...
TMPY-02634 IFNAR1 Protein, Human, Recombinant (hFc) Human HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPK-00889 IFNAR2 Protein, Human, Recombinant (aa 27-243, His) Human HEK293
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated...
TMPK-00637 IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) Cynomolgus HEK293
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-03829 IFNAR1 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His) Rhesus macaque Human Cells
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-...
TMPH-02732 IFNAR2 Protein, Mouse, Recombinant (His) Mouse Yeast
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
TMPY-01642 IFNAR2 Protein, Human, Recombinant (His) Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-04254 IFNAR1 Protein, Rhesus, Recombinant (His) Rhesus HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-03927 IFNAR1 Protein, Rhesus, Recombinant Rhesus HEK293
Interferon-alpha/beta receptor alpha chain (IFNAR1) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus prote...
TMPY-01640 IFNAR2 Protein, Human, Recombinant (hFc) Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-00139 IFNAR2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
IFNAR1 Protein, Human, Recombinant (His)
TMPY-02647
Species: Human
Expression System: HEK293
IFNAR1 Protein, Mouse, Recombinant (His)
TMPY-01489
Species: Mouse
Expression System: HEK293
IFNAR1 Protein, Mouse, Recombinant (hFc)
TMPK-00343
Species: Mouse
Expression System: HEK293
IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00326
Species: Human
Expression System: HEK293
IFNAR1 Protein, Mouse, Recombinant (His & Avi)
TMPK-00342
Species: Mouse
Expression System: HEK293
IFNAR1 Protein, Human, Recombinant (His & Avi)
TMPK-00325
Species: Human
Expression System: HEK293
IFNAR1 Protein, Human, Recombinant (hFc)
TMPY-02634
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (aa 27-243, His)
TMPK-00889
Species: Human
Expression System: HEK293
IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)
TMPK-00637
Species: Cynomolgus
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
IFNAR1 Protein, Rhesus, Recombinant (hFc)
TMPY-03829
Species: Rhesus
Expression System: HEK293
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00331
Species: Rhesus macaque
Expression System: Human Cells
IFNAR2 Protein, Mouse, Recombinant (His)
TMPH-02732
Species: Mouse
Expression System: Yeast
IFNAR2 Protein, Human, Recombinant (His)
TMPY-01642
Species: Human
Expression System: HEK293
IFNAR1 Protein, Rhesus, Recombinant (His)
TMPY-04254
Species: Rhesus
Expression System: HEK293
IFNAR1 Protein, Rhesus, Recombinant
TMPY-03927
Species: Rhesus
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (hFc)
TMPY-01640
Species: Human
Expression System: HEK293
IFNAR2 Protein, Cynomolgus, Recombinant (His)
TMPY-00139
Species: Cynomolgus
Expression System: HEK293
TargetMol